Author details

Full Name

Kai Ge

Affiliation

ORCID

Career Start Year

1995

Papers

119

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36604594	MLL3 loss drives metastasis by promoting a hybrid epithelial-mesenchymal transition state.		2023
36378541	BET Inhibitors Target the SCLC-N Subtype of Small-Cell Lung Cancer by Blocking NEUROD1 Transactivation.	Mol Cancer Res	2023
36797416	KDM6B protects T-ALL cells from NOTCH1-induced oncogenic stress.	Leukemia	2023
34583087	KDM6A Regulates Cell Plasticity and Pancreatic Cancer Progression by Noncanonical Activin Pathway.	Cellular and Molecular Gastroenterology and Hepatology	2022
36060646	Proteomic analysis of the liver regulating lipid metabolism in Chaohu ducks using two-dimensional electrophoresis.	Open Life Sciences	2022
35926054	JMJD3 activated hyaluronan synthesis drives muscle regeneration in an inflammatory environment.	Science	2022
36741385	Lysine methyltransferase Kmt2d regulates naive CD8 T cell activation-induced survival.		2022
34890228	MLL4 mediates differentiation and tumor suppression through ferroptosis.	Science advances	2021
33852868	UTX promotes CD8 TÂ cell-mediated antiviral defenses but reduces TÂ cell durability.	Cell Reports	2021
33712604	Interplay of BAF and MLL4 promotes cell type-specific enhancer activation.	Nature Communications	2021
31524052	Comparison of slaughter performance, meat traits, serum lipid parameters and fat tissue between Chaohu ducks with high- and low-intramuscular fat content.	Animal Biotechnology	2020
31968253	A Mouse Homolog of a Human TP53 Germline Mutation Reveals a Lipolytic Activity of p53.	Cell Reports	2020
32365172	H2B ubiquitylation enhances H3K4 methylation activities of human KMT2 family complexes.	Nucleic Acids Res	2020
32446320	Opposing Functions of BRD4 Isoforms in Breast Cancer.	Molecular Cell	2020
32994220	Molecular basis for histone H3 "K4me3-K9me3/2" methylation pattern readout by Spindlin1.	Journal of Biological Chemistry	2020
32601106	MLL3/MLL4-Associated PAGR1 Regulates Adipogenesis by Controlling Induction of C/EBPÎ² and C/EBPÎ´.	Molecular and Cellular Biology	2020
32544095	Histone methyltransferase MLL4 controls myofiber identity and muscle performance through MEF2 interaction.	Journal of Clinical Investigation	2020
32882322	Establishment of an SYBR Green-based real-time PCR assay for porcine circovirus type 4 detection.	Journal of Virological Methods	2020
32541010	The KMT2D Kabuki syndrome histone methylase controls neural crest cell differentiation and facial morphology.	Development (Cambridge)	2020
32817139	Lysine Demethylase KDM6A in Differentiation, Development, and Cancer.	Molecular and Cellular Biology	2020
32569721	Genomic and phylogenetic characteristics of a novel goose astrovirus in Anhui Province, Central-Eastern China.	Gene	2020
32668765	Loss of Function of the Gene Encoding the Histone Methyltransferase KMT2D Leads to Deregulation of Mitochondrial Respiration.	Cells	2020
30936246	Transcriptional and Epigenomic Regulation of Adipogenesis.	Molecular and Cellular Biology	2019
30335158	H3.3K4M destabilizes enhancer H3K4 methyltransferases MLL3/MLL4 and impairs adipose tissue development.	Nucleic Acids Research	2019
31127101	Selective binding of the PHD6 finger of MLL4 to histone H4K16ac links MLL4 and MOF.	Nat Commun	2019
31218175	Comparison of liver transcriptome from high- and low-intramuscular fat Chaohu ducks provided additional candidate genes for lipid selection.	3 Biotech	2019
31071089	Hypothalamic transcriptome analysis reveals the neuroendocrine mechanisms in controlling broodiness of Muscovy duck (Cairina moschata).	PLoS ONE	2019
31376351	Egg-laying and brooding stage-specific hormonal response and transcriptional regulation in pituitary of Muscovy duck (Cairina moschata).	Poultry Science	2019
31296899	High Fat Diet Triggers a Reduction in Body Fat Mass in Female Mice Deficient for Utx demethylase.	Scientific Reports	2019
29313530	Histone H3 lysine 4 monomethylation modulates long-range chromatin interactions at enhancers.	Cell Res	2018
30270123	HOXA9 Reprograms the Enhancer Landscape to Promote Leukemogenesis.	Cancer Cell	2018
29879809	Polymorphisms in the uncoupling protein 3 gene and their associations with feed efficiency in chickens.	Asian-Australasian Journal of Animal Sciences	2018
30297393	Histone methylation regulator PTIP is required to maintain normal and leukemic bone marrow niches.	Proc Natl Acad Sci U S A	2018
29911994	Fasting-induced JMJD3 histone demethylase epigenetically activates mitochondrial fatty acid Î²-oxidation.	Journal of Clinical Investigation	2018
29255264	Identification of H3K4me1-associated proteins at mammalian enhancers.	Nat Genet	2018
29077876	T3 and Glucose Coordinately Stimulate ChREBP-Mediated Ucp1 Expression in Brown Adipocytes From Male Mice.	Endocrinology	2018
29728617	Depletion of Nsd2-mediated histone H3K36 methylation impairs adipose tissue development and function.	Nature Communications	2018
29497152	Histone H3 lysine 4 monomethylation modulates long-range chromatin interactions at enhancers.	Cell Res	2018
29632194	In vivo CRISPR screening unveils histone demethylase UTX as an important epigenetic regulator in lung tumorigenesis.	Proceedings of the National Academy of Sciences of the United States of America	2018
27777310	Distinct Roles of Transcription Factors KLF4, Krox20, and Peroxisome Proliferator-Activated Receptor Î³ in Adipogenesis.	Molecular and Cellular Biology	2017
28728543	Integrative analysis of the Pekin duck (Anas anas) MicroRNAome during feather follicle development.	BMC Developmental Biology	2017
28759003	MLL4 prepares the enhancer landscape for Foxp3 induction via chromatin looping.	Nature Immunology	2017
28669924	Histone H3 lysine 4 methyltransferase KMT2D.	Gene	2017
28529687	Histone demethylases UTX and JMJD3 are required for NKT cell development in mice.	Cell and Bioscience	2017
28398509	MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis.	Nucleic Acids Research	2017
29263365	Brd4 binds to active enhancers to control cell identity gene induction in adipogenesis and myogenesis.	Nature Communications	2017
29073101	UTX-guided neural crest function underlies craniofacial features of Kabuki syndrome.	Proceedings of the National Academy of Sciences of the United States of America	2017
28013028	H3K4 Methyltransferase Activity Is Required for MLL4 Protein Stability.	Journal of Molecular Biology	2017
27777311	Glucocorticoid Receptor Accelerates, but Is Dispensable for, Adipogenesis.	Molecular and Cellular Biology	2017
27680696	Erratum: Replication fork stability confers chemoresistance in BRCA-deficient cells.	Nature	2016