|
| 36328144 | Neuroimaging uncovers neuronal and metabolic changes in pain modulatory brain areas in a rat model of chemotherapy-induced neuropathy - MEMRI and ex vivo spectroscopy studies. | Brain Res Bull | 2023 |
| 33495306 | Plitidepsin has potent preclinical efficacy against SARS-CoV-2 by targeting the host protein eEF1A. | Science | 2021 |
| 32264921 | CD13 as a new tumor target for antibody-drug conjugates: validation with the conjugate MI130110. | J Hematol Oncol | 2020 |
| 31761230 | Tailor-made PEG coated iron oxide nanoparticles as contrast agents for long lasting magnetic resonance molecular imaging of solid cancers. | Mater Sci Eng C Mater Biol Appl | 2020 |
| 32711367 | Plocabulin, a novel tubulin inhibitor, has potent antitumor activity in patient-derived xenograft models of gastrointestinal stromal tumors. | Transl Oncol | 2020 |
| 30831452 | Development of a new method for the quantitation of metabolites in the absence of chemically synthetized authentic standards. | J Pharm Biomed Anal | 2019 |
| 29127040 | Improved pharmacokinetic profile of lipophilic anti-cancer drugs using ανβ3-targeted polyurethane-polyurea nanoparticles. | Nanomedicine | 2018 |
| 29415678 | Plocabulin, a novel tubulin-binding agent, inhibits angiogenesis by modulation of microtubule dynamics in endothelial cells. | BMC Cancer | 2018 |
| 29440297 | MI130004, a Novel Antibody-Drug Conjugate Combining Trastuzumab with a Molecule of Marine Origin, Shows Outstanding <i>In Vivo</i> Activity against HER2-Expressing Tumors. | Mol Cancer Ther | 2018 |
| 26871278 | Development of a liquid chromatography/tandem mass spectrometry assay for the quantification of PM01183 (lurbinectedin), a novel antineoplastic agent, in mouse, rat, dog, Cynomolgus monkey and mini-pig plasma. | J Pharm Biomed Anal | 2016 |
| 27697767 | Lurbinectedin Inactivates the Ewing Sarcoma Oncoprotein EWS-FLI1 by Redistributing It within the Nucleus. | Cancer Res | 2016 |
| 27780828 | Lurbinectedin induces depletion of tumor-associated macrophages, an essential component of its in vivo synergism with gemcitabine, in pancreatic adenocarcinoma mouse models. | Dis Model Mech | 2016 |
| 25681727 | Enhanced in vivo therapeutic efficacy of plitidepsin-loaded nanocapsules decorated with a new poly-aminoacid-PEG derivative. | Int J Pharm | 2015 |
| 24486569 | PM060184, a new tubulin binding agent with potent antitumor activity including P-glycoprotein over-expressing tumors. | Biochem Pharmacol | 2014 |
| 24287622 | Nano-encapsulation of plitidepsin: in vivo pharmacokinetics, biodistribution, and efficacy in a renal xenograft tumor model. | Pharm Res | 2014 |
| 23591661 | A new potential nano-oncological therapy based on polyamino acid nanocapsules. | J Control Release | 2013 |
| 23697951 | c-Jun N-terminal kinase phosphorylation is a biomarker of plitidepsin activity. | Mar Drugs | 2013 |
| 22896654 | Lurbinectedin (PM01183), a new DNA minor groove binder, inhibits growth of orthotopic primary graft of cisplatin-resistant epithelial ovarian cancer. | Clin Cancer Res | 2012 |
| 20977459 | PM01183, a new DNA minor groove covalent binder with potent in vitro and in vivo anti-tumour activity. | Br J Pharmacol | 2010 |
| 19427997 | Molecular pharmacology and antitumor activity of Zalypsis in several human cancer cell lines. | Biochem Pharmacol | 2009 |
| 16497567 | Quantitative analysis of Variolin analog (PM01218) in mouse and rat plasma by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry. | J Chromatogr B Analyt Technol Biomed Life Sci | 2006 |
| 16921565 | Development of a liquid chromatography/tandem mass spectrometry assay for the quantification of PM02734, a novel antineoplastic agent, in dog plasma. | Rapid Commun Mass Spectrom | 2006 |
| 15702485 | Development of a liquid chromatography/tandem mass spectrometry assay for the quantification of PM00104, a novel antineoplastic agent, in mouse, rat, dog, and human plasma. | Rapid Commun Mass Spectrom | 2005 |
| 12888201 | Validation of a sensitive assay for thiocoraline in mouse plasma using liquid chromatography-tandem mass spectrometry. | J Chromatogr B Analyt Technol Biomed Life Sci | 2003 |
| 11557464 | Correlation between in vitro and in vivo activities of GM 237354, a new sordarin derivative, against Candida albicans in an in vitro pharmacokinetic-pharmacodynamic model and influence of protein binding. | Antimicrob Agents Chemother | 2001 |
| 11557470 | Animal pharmacokinetics and interspecies scaling of sordarin derivatives following intravenous administration. | Antimicrob Agents Chemother | 2001 |