Author details

Full Name

Peter W Zandstra

Affiliation

ORCID

Career Start Year

1994

Papers

171

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37503083	Cell networks in the mouse liver during partial hepatectomy.	bioRxiv	2023
36332630	Virtual cells in a virtual microenvironment recapitulate early development-like patterns in human pluripotent stem cell colonies.	Stem Cell Reports	2023
37928777	Engineering T Cell Development for the Next Generation of Stem Cell-Derived Immunotherapies.		2023
37090676	Sex biased human thymic architecture guides T cell development through spatially defined niches.	bioRxiv	2023
37188917	Author Correction: Deconvolution of clinical variance in CAR-T cell pharmacology and response.		2023
36790623	Inferring Gene Regulatory Networks and Predicting the Effect of Gene Perturbations via IQCELL.		2023
36849828	Deconvolution of clinical variance in CAR-T cell pharmacology and response.		2023
35087040	Multi-objective optimization reveals time- and dose-dependent inflammatory cytokine-mediated regulation of human stem cell derived T-cell development.	npj Regenerative Medicine	2022
36366891	Synthetic gene circuits for cell state detection and protein tuning in human pluripotent stem cells.	Molecular Systems Biology	2022
36001668	DLL4 and VCAM1 enhance the emergence of T cell-competent hematopoietic progenitors from human pluripotent stem cells.	Science advances	2022
36454756	Highly efficient reprogrammable mouse lines with integrated reporters to track the route to pluripotency.	Proc Natl Acad Sci U S A	2022
35213533	IQCELL: A platform for predicting the effect of gene perturbations on developmental trajectories using single-cell RNA-seq data.	PLoS Computational Biology	2022
33762663	Microdroplet-based one-step RT-PCR for ultrahigh throughput single-cell multiplex gene expression analysis and rare cell detection.	Scientific Reports	2021
33731744	Endogenous suppression of WNT signalling in human embryonic stem cells leads to low differentiation propensity towards definitive endoderm.	Scientific Reports	2021
31704264	Hematopoietic stem cell transplantation using single UM171-expanded cord blood: a single-arm, phase 1-2 safety and feasibility study.	Lancet Haematol	2020
32332853	A 96-well culture platform enables longitudinal analyses of engineered human skeletal muscle microtissue strength.	Scientific Reports	2020
31056479	Human Embryonic Stem Cell-Derived Cardiomyocytes Regenerate the Infarcted Pig Heart but Induce Ventricular Tachyarrhythmias.	Stem Cell Reports	2019
31634368	High-throughput micropatterning platform reveals Nodal-dependent bisection of peri-gastrulation-associated versus preneurulation-associated fate patterning.	PLoS Biology	2019
30601802	Context-explorer: Analysis of spatially organized protein expression in high-throughput screens.	PLoS Computational Biology	2019
30898844	Cell competition during reprogramming gives rise to dominant clones.	Science	2019
30784590	Identifying Extrinsic versus Intrinsic Drivers of Variation in Cell Behavior in Human iPSC Lines from Healthy Donors.	Cell Rep	2019
29769714	Author Correction: A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies.	Nature	2018
30307718	Patterned Optoelectronic Tweezers: A New Scheme for Selecting, Moving, and Storing Dielectric Particles and Cells.	Small	2018
29866848	Modulating cell state to enhance suspension expansion of human pluripotent stem cells.	Proceedings of the National Academy of Sciences of the United States of America	2018
30089805	Stem cell bioengineering: building from stem cell biology.	Nature Reviews Genetics	2018
29941948	Mechanics-guided developmental fate patterning.	Nature Materials	2018
29520230	Convenience versus Biological Significance: Are PMA-Differentiated THP-1 Cells a Reliable Substitute for Blood-Derived Macrophages When Studying Polarization?	Frontiers in Pharmacology	2018
29342133	A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies.	Nature	2018
29378814	Modeling signaling-dependent pluripotency with Boolean logic to predict cell fate transitions.	Mol Syst Biol	2018
29249665	FZD4 Marks Lateral Plate Mesoderm and Signals with NORRIN to Increase Cardiomyocyte Induction from Pluripotent Stem Cell-Derived Cardiac Progenitors.	Stem Cell Reports	2018
29679475	Chemically controlled aggregation of pluripotent stem cells.	Biotechnology and Bioengineering	2018
27827829	Distinct signaling programs control human hematopoietic stem cell survival and proliferation.	Blood	2017
28551499	Engineering cell fitness: lessons for regenerative medicine.	Current Opinion in Biotechnology	2017
28723184	Steric Hindrance Assay for Secreted Factors in Stem Cell Culture.	ACS Sensors	2017
28541275	Engineering the haemogenic niche mitigates endogenous inhibitory signals and controls pluripotent stem cell-derived blood emergence.	Nature Communications	2017
28870989	A stepwise model of reaction-diffusion and positional information governs self-organized human peri-gastrulation-like patterning.	Development (Cambridge)	2017
28394335	Progenitor T-cell differentiation from hematopoietic stem cells using Delta-like-4 and VCAM-1.	Nature Methods	2017
29263228	Enhanced human hematopoietic stem and progenitor cell engraftment by blocking donor T cell-mediated TNFÎ± signaling.	Sci Transl Med	2017
28253234	Engineering a humanized bone organ model in mice to study bone metastases.		2017
28061350	Achieving Efficient Manufacturing and Quality Assurance through Synthetic Cell Therapy Design.	Cell Stem Cell	2017
27535453	Distinguishing autocrine and paracrine signals in hematopoietic stem cell culture using a biofunctional microcavity platform.	Scientific Reports	2016
27054995	Quality cell therapy manufacturing by design.	Nature Biotechnology	2016
27009580	Signaling Networks among Stem Cell Precursors, Transit-Amplifying Progenitors, and their Niche in Developing Hair Follicles.	Cell Rep	2016
26832662	miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells.	Cancer Cell	2016
27132889	A Multi-Lineage Screen Reveals mTORC1 Inhibition Enhances Human Pluripotent Stem Cell Mesendoderm and Blood Progenitor Production.	Stem Cell Reports	2016
26858822	Two-dimensional arrays of cell-laden polymer hydrogel modules.	Biomicrofluidics	2016
27070706	miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells.	Cancer Cell	2016
27926740	A 17-gene stemness score for rapid determination of risk in acute leukaemia.	Nature	2016
27545711	Proneurogenic Ligands Defined by Modeling Developing Cortex Growth Factor Communication Networks.	Neuron	2016
26076835	CD24 tracks divergent pluripotent states in mouse and human cells.	Nat Commun	2015