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Author Details

Ben Readhead
2013
59
25
PMIDPaper TitleJournal TitlePublished Year
36657633BCI-838, an orally active mGluR2/3 receptor antagonist pro-drug, rescues learning behavior deficits in the PS19 MAPT<sup>P301S</sup> mouse model of tauopathy.Neurosci Lett2023
35998281Saracatinib, a Selective Src Kinase Inhibitor, Blocks Fibrotic Responses in Preclinical Models of Pulmonary Fibrosis.Am J Respir Crit Care Med2022
34993477Deep learning-based brain transcriptomic signatures associated with the neuropathological and clinical severity of Alzheimer's disease.Brain Commun2021
33972690The viral hypothesis: how herpesviruses may contribute to Alzheimer's disease.Mol Psychiatry2021
33619496Mapping of SARS-CoV-2 Brain Invasion and Histopathology in COVID-19 Disease.medRxiv2021
34352486Systems modeling of metabolic dysregulation in neurodegenerative diseases.Curr Opin Pharmacol2021
33095911An additional drug repurposing study for hidradenitis suppurativa/acne inversa.Br J Dermatol2021
34675338Repositioning of a novel GABA-B receptor agonist, AZD3355 (Lesogaberan), for the treatment of non-alcoholic steatohepatitis.Sci Rep2021
32666270miR155 regulation of behavior, neuropathology, and cortical transcriptomics in Alzheimer's disease.Acta Neuropathol2020
32064044Sexual dimorphism in atrophic effects of topical glucocorticoids is driven by differential regulation of atrophogene REDD1 in male and female skin.Oncotarget2020
31838778Alterations in innate immunity and epithelial cell differentiation are the molecular pillars of hidradenitis suppurativa.J Eur Acad Dermatol Venereol2020
32152461Do infections have a role in the pathogenesis of Alzheimer disease?Nat Rev Neurol2020
32454811Systematic Analysis of Environmental Chemicals That Dysregulate Critical Period Plasticity-Related Gene Expression Reveals Common Pathways That Mimic Immune Response to Pathogen.Neural Plast2020
32546661A Novel Approach to Safer Glucocorticoid Receptor-Targeted Anti-lymphoma Therapy via REDD1 (Regulated in Development and DNA Damage 1) Inhibition.Mol Cancer Ther2020
33298155Longitudinal data in peripheral blood confirm that PM20D1 is a quantitative trait locus (QTL) for Alzheimer's disease and implicate its dynamic role in disease progression.Clin Epigenetics2020
31345219Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits.BMC Med Genomics2019
31855627Clarifying the Potential Role of Microbes in Alzheimer's Disease.Neuron2019
31684948Correction to: Integrative analysis of loss-of-function variants in clinical and genomic data reveals novel genes associated with cardiovascular traits.BMC Med Genomics2019
30442475Critical period plasticity-related transcriptional aberrations in schizophrenia and bipolar disorder.Schizophr Res2019
30283032Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burden.Mol Psychiatry2019
30464330Correction: Integrative approach to sporadic Alzheimer's disease: deficiency of TYROBP in cerebral Aβ amyloidosis mouse normalizes clinical phenotype and complement subnetwork molecular pathology without reducing Aβ burden.Mol Psychiatry2019
31444360Integrative transcriptome imputation reveals tissue-specific and shared biological mechanisms mediating susceptibility to complex traits.Nat Commun2019
31266448Genome-wide analysis indicates association between heterozygote advantage and healthy aging in humans.BMC Genet2019
30737086PI3K inhibitors protect against glucocorticoid-induced skin atrophy.EBioMedicine2019
31059280Systems Pharmacology Identifies an Arterial Wall Regulatory Gene Network Mediating Coronary Artery Disease Side Effects of Antiretroviral Therapy.Circ Genom Precis Med2019
31247200Transcriptomic Network Interactions in Human Skin Treated with Topical Glucocorticoid Clobetasol Propionate.J Invest Dermatol2019
28200013Systematic analyses of drugs and disease indications in RepurposeDB reveal pharmacological, biological and epidemiological factors influencing drug repositioning.Brief Bioinform2018
28642592Integrative network analysis identifies novel drivers of pathogenesis and progression in newly diagnosed multiple myeloma.Leukemia2018
29888052A Network-Biology Informed Computational Drug Repositioning Strategy to Target Disease Risk Trajectories and Comorbidities of Peripheral Artery Disease.AMIA Jt Summits Transl Sci Proc2018
30451900Author Correction: Expression-based drug screening of neural progenitor cells from individuals with schizophrenia.Nat Commun2018
30356048Expression-based drug screening of neural progenitor cells from individuals with schizophrenia.Nat Commun2018
30255805Pharmacological risk factors associated with hospital readmission rates in a psychiatric cohort identified using prescriptome data mining.BMC Med Inform Decis Mak2018
30410676Deletion of the glucocorticoid receptor chaperone FKBP51 prevents glucocorticoid-induced skin atrophy.Oncotarget2018
29937276Multiscale Analysis of Independent Alzheimer's Cohorts Finds Disruption of Molecular, Genetic, and Clinical Networks by Human Herpesvirus.Neuron2018
29289717Exploring the Interaction Between eIF2α Dysregulation, Acute Endoplasmic Reticulum Stress and DYT1 Dystonia in the Mammalian Brain.Neuroscience2018
29596905Rapamycin Modulates Glucocorticoid Receptor Function, Blocks Atrophogene REDD1, and Protects Skin from Steroid Atrophy.J Invest Dermatol2018
29364887Mutations in THAP1/DYT6 reveal that diverse dystonia genes disrupt similar neuronal pathways and functions.PLoS Genet2018
27989886Intracoronary Imaging, Cholesterol Efflux, and Transcriptomes After Intensive Statin Treatment: The YELLOW II Study.J Am Coll Cardiol2017
28758999Necroptosis activation in Alzheimer's disease.Nat Neurosci2017
28877483Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells.Cell Rep2017
28612290Deficiency of TYROBP, an adapter protein for TREM2 and CR3 receptors, is neuroprotective in a mouse model of early Alzheimer's pathology.Acta Neuropathol2017
30062151Enabling Precision Cardiology Through Multiscale Biology and Systems Medicine.JACC Basic Transl Sci2017
28051114Novel Therapeutics Identification for Fibrosis in Renal Allograft Using Integrative Informatics Approach.Sci Rep2017
27668389Gene expression elucidates functional impact of polygenic risk for schizophrenia.Nat Neurosci2016
28413689L1000CDS<sup>2</sup>: LINCS L1000 characteristic direction signatures search engine.NPJ Syst Biol Appl2016
27390852Systems Genetic Analyses Highlight a TGFβ-FOXO3 Dependent Striatal Astrocyte Network Conserved across Species and Associated with Stress, Sleep, and Huntington's Disease.PLoS Genet2016
27135365Cross-Tissue Regulatory Gene Networks in Coronary Artery Disease.Cell Syst2016
26915512Polygenic overlap between schizophrenia risk and antipsychotic response: a genomic medicine approach.Lancet Psychiatry2016
27174811Systems Medicine Approaches to Improving Understanding, Treatment, and Clinical Management of Neuroendocrine Prostate Cancer.Curr Pharm Des2016
26782051Molecular systems evaluation of oligomerogenic APP(E693Q) and fibrillogenic APP(KM670/671NL)/PSEN1(οexon9) mouse models identifies shared features with human Alzheimer's brain molecular pathology.Mol Psychiatry2016
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