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Author Details

Ken Chen
University of Texas MD Anderson Cancer Center
2007
158
57
PMIDPaper TitleJournal TitlePublished Year
38042257Ex Vivo Expanded Cord Blood Natural Killer Cells Combined with Rituximab and High-Dose Chemotherapy and Autologous Stem Cell Transplantation for B Cell Non-Hodgkin Lymphoma.Transplant Cell Ther2024
37592035Single-nucleotide variant calling in single-cell sequencing data with Monopogen.Nat Biotechnol2024
37091228Identifying signatures of EV secretion in metastatic breast cancer through functional single-cell profiling.iScience2023
37479893Single-cell chromatin accessibility profiling of acute myeloid leukemia reveals heterogeneous lineage composition upon therapy-resistance.Commun Biol2023
37547002Batch-Corrected Distance Mitigates Temporal and Spatial Variability for Clustering and Visualization of Single-Cell Gene Expression Data.Res Sq2023
37573313Characterizing cancer metabolism from bulk and single-cell RNA-seq data using METAFlux.Nat Commun2023
37538987Integrative Prognostic Machine Learning Models in Mantle Cell Lymphoma.Cancer Res Commun2023
37494448Loss of metabolic fitness drives tumor resistance after CAR-NK cell therapy and can be overcome by cytokine engineering.Sci Adv2023
36993682An interpretable ML model to characterize patient-specific HLA-I antigen presentation.bioRxiv2023
37454202Actionability classification of variants of unknown significance correlates with functional effect.NPJ Precis Oncol2023
37380767A spatially resolved single-cell genomic atlas of the adult human breast.Nature2023
35108036Clinical and Molecular Characterization of <i>POLE</i> Mutations as Predictive Biomarkers of Response to Immune Checkpoint Inhibitors in Advanced Cancers.JCO Precis Oncol2022
35534898Bi-order multimodal integration of single-cell data.Genome Biol2022
35752636Occult polyclonality of preclinical pancreatic cancer models drives in vitro evolution.Nat Commun2022
36518525Single-cell CRISPR immune screens reveal immunological roles of tumor intrinsic factors.NAR Cancer2022
36543374Activated B cells suppress T-cell function through metabolic competition.J Immunother Cancer2022
35941212A phase two study of high dose blinatumomab in Richter's syndrome.Leukemia2022
36241426Direct CD32 T-cell cytotoxicity: implications for breast cancer prognosis and treatment.Life Sci Alliance2022
36175679KIR-based inhibitory CARs overcome CAR-NK cell trogocytosis-mediated fratricide and tumor escape.Nat Med2022
35995947Spatially restricted drivers and transitional cell populations cooperate with the microenvironment in untreated and chemo-resistant pancreatic cancer.Nat Genet2022
36008138KLF5 governs sphingolipid metabolism and barrier function of the skin.Genes Dev2022
34983369Sensei: how many samples to tell a change in cell type abundance?BMC Bioinformatics2022
35252817Spatially resolved transcriptomics of high-grade serous ovarian carcinoma.iScience2022
35314812Spatial charting of single-cell transcriptomes in tissues.Nat Biotechnol2022
34914826Blinatumomab maintenance after allogeneic hematopoietic cell transplantation for B-lineage acute lymphoblastic leukemia.Blood2022
35181783BHLHE40 Regulates the T-Cell Effector Function Required for Tumor Microenvironment Remodeling and Immune Checkpoint Therapy Efficacy.Cancer Immunol Res2022
32902645Targeting a cytokine checkpoint enhances the fitness of armored cord blood CAR-NK cells.Blood2021
36969355Single-cell manifold-preserving feature selection for detecting rare cell populations.Nat Comput Sci2021
33912187Response to Hypomethylating Agents in Myelodysplastic Syndrome Is Associated With Emergence of Novel TCR Clonotypes.Front Immunol2021
33717142GMP-Compliant Universal Antigen Presenting Cells (uAPC) Promote the Metabolic Fitness and Antitumor Activity of Armored Cord Blood CAR-NK Cells.Front Immunol2021
33875650Spatially interacting phosphorylation sites and mutations in cancer.Nat Commun2021
33622385MEDALT: single-cell copy number lineage tracing enabling gene discovery.Genome Biol2021
33782032Genomic, Transcriptomic, and Proteomic Profiling of Metastatic Breast Cancer.Clin Cancer Res2021
34518211Oxidative Phosphorylation Is a Metabolic Vulnerability in Chemotherapy-Resistant Triple-Negative Breast Cancer.Cancer Res2021
34422660Decoupling Lineage-Associated Genes in Acute Myeloid Leukemia Reveals Inflammatory and Metabolic Signatures Associated With Outcomes.Front Oncol2021
34017325Metabolic Reprogramming of GMP Grade Cord Tissue Derived Mesenchymal Stem Cells Enhances Their Suppressive Potential in GVHD.Front Immunol2021
34270918Generation of glucocorticoid-resistant SARS-CoV-2 T cells for adoptive cell therapy.Cell Rep2021
33986022Combining AFM13, a Bispecific CD30/CD16 Antibody, with Cytokine-Activated Blood and Cord Blood-Derived NK Cells Facilitates CAR-like Responses Against CD30<sup>+</sup> Malignancies.Clin Cancer Res2021
34117319Extended live-cell barcoding approach for multiplexed mass cytometry.Sci Rep2021
34337565Uncoupling of gene expression from copy number presents therapeutic opportunities in aneuploid cancers.Cell Rep Med2021
34232885Stratified Test Accurately Identifies Differentially Expressed Genes Under Batch Effects in Single-Cell Data.IEEE/ACM Trans Comput Biol Bioinform2021
34138753Targeting the αv integrin/TGF-β axis improves natural killer cell function against glioblastoma stem cells.J Clin Invest2021
33462507Delineating copy number and clonal substructure in human tumors from single-cell transcriptomes.Nat Biotechnol2021
33342071Ab initio spillover compensation in mass cytometry data.Cytometry A2021
33398161Single-cell dissection of intratumoral heterogeneity and lineage diversity in metastatic gastric adenocarcinoma.Nat Med2021
32541955A robust benchmark for detection of germline large deletions and insertions.Nat Biotechnol2020
33052339Batch-Corrected Distance Mitigates Temporal and Spatial Variability for Clustering and Visualization of Single-Cell Gene Expression Data.bioRxiv2020
32995792Generation of glucocorticoid resistant SARS-CoV-2 T-cells for adoptive cell therapy.bioRxiv2020
32699374Author Correction: A robust benchmark for detection of germline large deletions and insertions.Nat Biotechnol2020
32188848Latent periodic process inference from single-cell RNA-seq data.Nat Commun2020
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Jean-Pierre A Kocher
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Collaborators

Li Ding
McDonnell Genome Institute, Washington University School of Medicine
Co-authored papers 42
Gordon B Mills
Knight Cancer Institute, Oregon Health and Sciences University
Co-authored papers 40
Funda Meric-Bernstam
University of Texas MD Anderson Cancer Center
Co-authored papers 38
Kenna R Mills Shaw
The University of Texas MD Anderson Cancer Center
Co-authored papers 26
Richard K Wilson
The Ohio State University
Co-authored papers 23
Elaine R Mardis
The Ohio State University
Co-authored papers 22
Michael C Wendl
Washington University in St Louis
Co-authored papers 19
Michael D McLellan
McDonnell Genome Institute, Washington University in St. Louis
Co-authored papers 19
David E Larson
McDonnell Genome Institute, Washington University School of Medicine
Co-authored papers 18
Daniel C Koboldt
Institute for Genomic Medicine, Nationwide Children's Hospital
Co-authored papers 17
Timothy J Ley
Washington University School of Medicine
Co-authored papers 16
Xian Fan
Rice University
Co-authored papers 15
Robert S Fulton
McDonnell Genome Institute, Washington University School of Medicine
Co-authored papers 15
Zechen Chong
Heersink School of Medicine, University of Alabama at Birmingham
Co-authored papers 14
Beom-Jun Kim
Asan Medical Center, University of Ulsan College of Medicine
Co-authored papers 13
Mark J Routbort
University of Texas MD Anderson Cancer Center
Co-authored papers 11
Lucinda Fulton
McDonnell Genome Institute, Washington University School of Medicine
Co-authored papers 11
Scott Kopetz
University of Texas MD Anderson Cancer Center
Co-authored papers 11
Wanding Zhou
University of Pennsylvania
Co-authored papers 10
Mark A Watson
Washington University School of Medicine
Co-authored papers 10
Joshua F McMichael
Washington University
Co-authored papers 9
Alexander J Lazar
The University of Texas MD Anderson Cancer Center
Co-authored papers 8
Matthew A Wyczalkowski
Washington University in St Louis
Co-authored papers 8
Sharon E Heath
Washington University School of Medicine.
Co-authored papers 8
Timothy A Graubert
Massachusetts General Hospital
Co-authored papers 8
Jacqueline E Payton
Washington University School of Medicine.
Co-authored papers 8
John F DiPersio
Washington University School of Medicine
Co-authored papers 8
Daniel C Link
Washington University School of Medicine
Co-authored papers 7
Sean McGrath
Harvard T.H. Chan School of Public Health
Co-authored papers 7
Matthew J Walter
Washington University School of Medicine in St. Louis
Co-authored papers 7
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