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Author Details

Severa Bunda
Princess Margaret Cancer Centre
2005
27
17
PMIDPaper TitleJournal TitlePublished Year
37164978Multiplatform molecular profiling uncovers two subgroups of malignant peripheral nerve sheath tumors with distinct therapeutic vulnerabilities.Nat Commun2023
37171636Correction: Increased mRNA expression of CDKN2A is a transcriptomic marker of clinically aggressive meningiomas.Acta Neuropathol2023
37474126Integrated molecular analysis reveals hypermethylation and overexpression of HOX genes to be poor prognosticators in isocitrate dehydrogenase mutant glioma.Neuro Oncol2023
33611710Clinical significance of checkpoint regulator "Programmed death ligand-1 (PD-L1)" expression in meningioma: review of the current status.J Neurooncol2021
33853689TNFα secreted by glioma associated macrophages promotes endothelial activation and resistance against anti-angiogenic therapy.Acta Neuropathol Commun2021
33925295Liquid Biomarkers for Improved Diagnosis and Classification of CNS Tumors.Int J Mol Sci2021
32029440c-Src Phosphorylates and Inhibits the Function of the CIC Tumor Suppressor Protein.Mol Cancer Res2020
30322879Ketoconazole and Posaconazole Selectively Target HK2-expressing Glioblastoma Cells.Clin Cancer Res2019
30737375CIC protein instability contributes to tumorigenesis in glioblastoma.Nat Commun2019
29232550Glut3 Addiction: A Druggable Vulnerability in Glioblastoma.Cancer Cell2017
26846855Oxygen-dependent Regulation of Erythropoietin Receptor Turnover and Signaling.J Biol Chem2016
24469048Juvenile myelomonocytic leukaemia-associated mutation in Cbl promotes resistance to apoptosis via the Lyn-PI3K/AKT pathway.Oncogene2015
26617336Inhibition of SHP2-mediated dephosphorylation of Ras suppresses oncogenesis.Nat Commun2015
25157176Src promotes GTPase activity of Ras via tyrosine 32 phosphorylation.Proc Natl Acad Sci U S A2014
23400592Inhibition of SRC corrects GM-CSF hypersensitivity that underlies juvenile myelomonocytic leukemia.Cancer Res2013
24086733SOCS-1 mediates ubiquitylation and degradation of GM-CSF receptor.PLoS One2013
21685897Loss of JAK2 regulation via a heterodimeric VHL-SOCS1 E3 ubiquitin ligase underlies Chuvash polycythemia.Nat Med2011
21880723Retinoblastoma protein modulates the inverse relationship between cellular proliferation and elastogenesis.J Biol Chem2011
20100694Desialylation of insulin receptors and IGF-1 receptors by neuraminidase-1 controls the net proliferative response of L6 myoblasts to insulin.Glycobiology2010
20694012Germline CBL mutations cause developmental abnormalities and predispose to juvenile myelomonocytic leukemia.Nat Genet2010
20947500The hyperthermia-enhanced association between tropoelastin and its 67-kDa chaperone results in better deposition of elastic fibers.J Biol Chem2010
20535129Aldosterone and mineralocorticoid receptor antagonists modulate elastin and collagen deposition in human skin.J Invest Dermatol2010
19372600Aldosterone stimulates elastogenesis in cardiac fibroblasts via mineralocorticoid receptor-independent action involving the consecutive activation of Galpha13, c-Src, the insulin-like growth factor-I receptor, and phosphatidylinositol 3-kinase/Akt.J Biol Chem2009
18772331Neuraminidase-1, a subunit of the cell surface elastin receptor, desialylates and functionally inactivates adjacent receptors interacting with the mitogenic growth factors PDGF-BB and IGF-2.Am J Pathol2008
17724138Aldosterone induces elastin production in cardiac fibroblasts through activation of insulin-like growth factor-I receptors in a mineralocorticoid receptor-independent manner.Am J Pathol2007
16543900Serum factors from pseudoxanthoma elasticum patients alter elastic fiber formation in vitro.J Invest Dermatol2006
15537639Fluctuations of intracellular iron modulate elastin production.J Biol Chem2005
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Collaborators

Gelareh Zadeh
University of Toronto
Co-authored papers 12
Kenneth Aldape
National Cancer Institute
Co-authored papers 8
Farshad Nassiri
Toronto Western Hospital, University Health Network, University of Toronto
Co-authored papers 5
Olivia Singh
Princess Margaret Cancer Centre
Co-authored papers 5
Shirin Karimi
Princess Margaret Cancer Centre
Co-authored papers 4
Brian Raught
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 3
Vikas Patil
Princess Margaret Hospital
Co-authored papers 3
Mignon L Loh
University of Washington
Co-authored papers 2
Sameer Agnihotri
Co-authored papers 2
Andreas von Deimling
Co-authored papers 2
Qingxia Wei
Princess Margaret Cancer Centre, University Health Network and University of Toronto
Co-authored papers 2
Peter P Liu
Co-authored papers 2
Zhong-Yin Zhang
Center for Cancer Research, and Institute for Drug Discovery, Purdue University
Co-authored papers 1
Priscilla K Brastianos
Co-authored papers 1
Felix Behling
University Hospital Tubingen, Eberhard-Karls-University Tubingen
Co-authored papers 1
Bharati Mehani
Center for Cancer Research, National Cancer Institute
Co-authored papers 1
Andrew Gao
University Health Network
Co-authored papers 1
Helin Dogan
University Hospital Heidelberg (DKFZ)
Co-authored papers 1
Marcos Tatagiba
University of Tubingen
Co-authored papers 1
Sara Arab
Co-authored papers 1
Benjamin S Braun
Benioff Children's Hospitals, University of California san francisco
Co-authored papers 1
Rebecca Yakubov
Princess Margaret Cancer Centre, University Health Network and University of Toronto
Co-authored papers 1
Mareike Simon
Abramson Family Cancer Research Institute, Perelman School of Medicine
Co-authored papers 1
Jeff Liu
Princess Margaret Cancer Centre, University Health Network and University of Toronto
Co-authored papers 1
Marco Skardelly
University Hospital Tubingen, Eberhard-Karls-University Tubingen
Co-authored papers 1
Sebastian Brandner
UCL Queen Square Institute of Neurology
Co-authored papers 1
Charlotte M Niemeyer
Co-authored papers 1
Aaron A Cohen-Gadol
Indiana University
Co-authored papers 1
David R Raleigh
University of California san francisco
Co-authored papers 1
Paul C Boutros
University of California los angeles
Co-authored papers 1
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