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Author Details

Edward L Huttlin
Harvard Medical School
2006
62
36
Emma Lundberg (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36593396A proteome-wide atlas of drug mechanism of action.Nat Biotechnol2023
38065956Quantitative proteomics defines mechanisms of antiviral defence and cell death during modified vaccinia Ankara infection.Nat Commun2023
37311461An Epstein-Barr virus protein interaction map reveals NLRP3 inflammasome evasion via MAVS UFMylation.Mol Cell2023
37302069Proteomic analysis of circulating immune cells identifies cellular phenotypes associated with COVID-19 severity.Cell Rep2023
36919909Human Polo-like Kinase Inhibitors as Antiplasmodials.ACS Infect Dis2023
36732331Sample multiplexing-based targeted pathway proteomics with real-time analytics reveals the impact of genetic variation on protein expression.Nat Commun2023
36794911BioPlexR and BioPlexPy: integrated data products for the analysis of human protein interactions.Bioinformatics2023
36334589Architecture of the outbred brown fat proteome defines regulators of metabolic physiology.Cell2022
35672473Author Correction: Defining the consequences of genetic variation on a proteome-wide scale.Nature2022
36280721A multi-purpose, regenerable, proteome-scale, human phosphoserine resource for phosphoproteomics.Nat Methods2022
33961781Dual proteome-scale networks reveal cell-specific remodeling of the human interactome.Cell2021
34819669A multi-scale map of cell structure fusing protein images and interactions.Nature2021
34626566Proteome-wide mapping of short-lived proteins in human cells.Mol Cell2021
32126768Full-Featured, Real-Time Database Searching Platform Enables Fast and Accurate Multiplexed Quantitative Proteomics.J Proteome Res2020
32243163Selection of Heating Temperatures Improves the Sensitivity of the Proteome Integral Solubility Alteration Assay.J Proteome Res2020
32109415A Quantitative Tissue-Specific Landscape of Protein Redox Regulation during Aging.Cell2020
32203386TMTpro reagents: a set of isobaric labeling mass tags enables simultaneous proteome-wide measurements across 16 samples.Nat Methods2020
31722220Investigation of Proteomic and Phosphoproteomic Responses to Signaling Network Perturbations Reveals Functional Pathway Organizations in Yeast.Cell Rep2019
31873071Human cytomegalovirus interactome analysis identifies degradation hubs, domain associations and viral protein functions.Elife2019
29195270Compositional Proteomics: Effects of Spatial Constraints on Protein Quantification Utilizing Isobaric Tags.J Proteome Res2018
30122656High-Definition Analysis of Host Protein Stability during Human Cytomegalovirus Infection Reveals Antiviral Factors and Viral Evasion Mechanisms.Cell Host Microbe2018
29678115Characterization of Plasmodium falciparum Atypical Kinase PfPK7<sup>-</sup> Dependent Phosphoproteome.J Proteome Res2018
29396030DNAJC12: A molecular chaperone involved in proteostasis, PKU, biogenic amines metabolism and beyond?Mol Genet Metab2018
29054129BioPlex Display: An Interactive Suite for Large-Scale AP-MS Protein-Protein Interaction Data.J Proteome Res2018
27978624Neutral Loss Is a Very Common Occurrence in Phosphotyrosine-Containing Peptides Labeled with Isobaric Tags.J Proteome Res2017
28132689Biallelic Mutations in DNAJC12 Cause Hyperphenylalaninemia, Dystonia, and Intellectual Disability.Am J Hum Genet2017
29038162Systematic Analysis of Human Cells Lacking ATG8 Proteins Uncovers Roles for GABARAPs and the CCZ1/MON1 Regulator C18orf8/RMC1 in Macroautophagic and Selective Autophagic Flux.Mol Cell Biol2017
28514442Architecture of the human interactome defines protein communities and disease networks.Nature2017
26911913Corrigendum: Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis.Nat Cell Biol2016
27309819Defining the consequences of genetic variation on a proteome-wide scale.Nature2016
25997101QIL1 is a novel mitochondrial protein required for MICOS complex stability and cristae morphology.Elife2015
26252148Erratum: A mass-tolerant database search identifies a large proportion of unassigned spectra in shotgun proteomics as modified peptides.Nat Biotechnol2015
26389662Systematic proteomics of the VCP-UBXD adaptor network identifies a role for UBXN10 in regulating ciliogenesis.Nat Cell Biol2015
26186194The BioPlex Network: A Systematic Exploration of the Human Interactome.Cell2015
26051181Quantitative Proteomic Atlas of Ubiquitination and Acetylation in the DNA Damage Response.Mol Cell2015
26076430A mass-tolerant database search identifies a large proportion of unassigned spectra in shotgun proteomics as modified peptides.Nat Biotechnol2015
24344204TIMMDC1/C3orf1 functions as a membrane-embedded mitochondrial complex I assembly factor through association with the MCIA complex.Mol Cell Biol2014
24927332MultiNotch MS3 enables accurate, sensitive, and multiplexed detection of differential expression across cancer cell line proteomes.Anal Chem2014
24906157Quantitative temporal viromics: an approach to investigate host-pathogen interaction.Cell2014
24532714Proteomic analysis of cap-dependent translation identifies LARP1 as a key regulator of 5'TOP mRNA translation.Genes Dev2014
23503661Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.Nature2013
23914800Global analysis of protein expression and phosphorylation of three stages of Plasmodium falciparum intraerythrocytic development.J Proteome Res2013
23924158Candidate serum biomarkers for early intestinal cancer using 15N metabolic labeling and quantitative proteomics in the ApcMin/+ mouse.J Proteome Res2013
23607489Mass spectrometry based method to increase throughput for kinome analyses using ATP probes.Anal Chem2013
23401857Gab2 phosphorylation by RSK inhibits Shp2 recruitment and cell motility.Mol Cell Biol2013
22880955Increasing the multiplexing capacity of TMTs using reporter ion isotopologues with isobaric masses.Anal Chem2012
22966201Phosphorylation of the eukaryotic translation initiation factor 4E-transporter (4E-T) by c-Jun N-terminal kinase promotes stress-dependent P-body assembly.Mol Cell Biol2012
21725298A large-scale method to measure absolute protein phosphorylation stoichiometries.Nat Methods2011
21917720Evaluation of HCD- and CID-type fragmentation within their respective detection platforms for murine phosphoproteomics.Mol Cell Proteomics2011
21906983Systematic and quantitative assessment of the ubiquitin-modified proteome.Mol Cell2011
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Collaborators

Harvard Medical School
Co-authored papers 41
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Co-authored papers 13
Harvard Medical School
Co-authored papers 9
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Co-authored papers 6
Tufts University
Co-authored papers 4
Institute for Research in Immunology and Cancer (IRIC), Universite de Montreal
Co-authored papers 3
IRIC - University of Montreal
Co-authored papers 3
Harvard Medical School
Co-authored papers 2
Center for Computational Sciences
Co-authored papers 2
Institute for Research in Immunology and Cancer (IRIC)
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
University of Wisconsin School of Medicine and Public Health
Co-authored papers 1
Co-authored papers 1
Center for Computational Biomedicine, Harvard Medical School
Co-authored papers 1
University of California San Diego
Co-authored papers 1
Co-authored papers 1
Universite libre de Bruxelles (ULB)
Co-authored papers 1
University of California San Diego
Co-authored papers 1
University of California San Diego
Co-authored papers 1
University of California San Diego san francisco
Co-authored papers 1
University of California San Diego
Co-authored papers 1
University of California San Diego
Co-authored papers 1
Harvard Medical School
Co-authored papers 1
University of California San Diego
Co-authored papers 1
Memorial Sloan Kettering Cancer Center
Co-authored papers 1
Cell Signaling Technology Inc.
Co-authored papers 1
University of Washington
Co-authored papers 1