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Author Details
Full Name
Lori S Hart
Affiliation
Children's Hospital of Philadelphia, USA. [2] Center for Childhood Cancer Research
ORCID
Career Start Year
1987
Papers
31
H Index
23
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
32211329
CAMKV Is a Candidate Immunotherapeutic Target in <i>MYCN</i> Amplified Neuroblastoma.
Front Oncol
2020
32029721
Acetate supplementation restores chromatin accessibility and promotes tumor cell differentiation under hypoxia.
Cell Death Dis
2020
32307821
Limited antitumor activity of combined BET and MEK inhibition in neuroblastoma.
Pediatr Blood Cancer
2020
31693904
Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design.
Cell Rep
2019
27729458
Preclinical Therapeutic Synergy of MEK1/2 and CDK4/6 Inhibition in Neuroblastoma.
Clin Cancer Res
2017
28350380
Transcriptomic profiling of 39 commonly-used neuroblastoma cell lines.
Sci Data
2017
29206221
Corrigendum: Transcriptomic profiling of 39 commonly-used neuroblastoma cell lines.
Sci Data
2017
27986745
Dual <i>ALK</i> and <i>CDK4/6</i> Inhibition Demonstrates Synergy against Neuroblastoma.
Clin Cancer Res
2017
26121087
Relapsed neuroblastomas show frequent RAS-MAPK pathway mutations.
Nat Genet
2015
26560027
Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism.
Nature
2015
24569374
Targeting ER stress-induced autophagy overcomes BRAF inhibitor resistance in melanoma.
J Clin Invest
2014
23849696
Inhibition of Hsp27 radiosensitizes head-and-neck cancer by modulating deoxyribonucleic acid repair.
Int J Radiat Oncol Biol Phys
2013
24045179
Dual CDK4/CDK6 inhibition induces cell-cycle arrest and senescence in neuroblastoma.
Clin Cancer Res
2013
23143306
ER stress-mediated autophagy promotes Myc-dependent transformation and tumor growth.
J Clin Invest
2012
21646472
Overcoming hypoxia-induced apoptotic resistance through combinatorial inhibition of GSK-3β and CDK1.
Cancer Res
2011
21975022
High-resolution imaging and antitumor effects of GFP(+) bone marrow-derived cells homing to syngeneic mouse colon tumors.
Am J Pathol
2011
21720213
Human colon cancer stem cells are enriched by insulin-like growth factor-1 and are sensitive to figitumumab.
Cell Cycle
2011
21653830
Off-target lapatinib activity sensitizes colon cancer cells through TRAIL death receptor up-regulation.
Sci Transl Med
2011
20473272
The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation.
EMBO J
2010
19632170
Cell death: a new Par-4 the TRAIL.
Cell
2009
19923910
The combination of 5-fluorouracil plus p53 pathway restoration is associated with depletion of p53-deficient or mutant p53-expressing putative colon cancer stem cells.
Cancer Biol Ther
2009
19923899
Visualization and enrichment of live putative cancer stem cell populations following p53 inactivation or Bax deletion using non-toxic fluorescent dyes.
Cancer Biol Ther
2009
20054236
The p53 target Plk2 interacts with TSC proteins impacting mTOR signaling, tumor growth and chemosensitivity under hypoxic conditions.
Cell Cycle
2009
18182481
OSU-03012 stimulates PKR-like endoplasmic reticulum-dependent increases in 70-kDa heat shock protein expression, attenuating its lethal actions in transformed cells.
Mol Pharmacol
2008
18539971
Invincible, but not invisible: imaging approaches toward in vivo detection of cancer stem cells.
J Clin Oncol
2008
17172468
The adenoviral E4orf6 protein induces atypical apoptosis in response to DNA damage.
J Biol Chem
2007
17912032
Effects of low confluency, serum starvation and hypoxia on the side population of cancer cell lines.
Cell Cycle
2007
17881904
Chemotherapy-resistant side-population of colon cancer cells has a higher sensitivity to TRAIL than the non-SP, a higher expression of c-Myc and TRAIL-receptor DR4.
Cancer Biol Ther
2007
16704987
Arachidonic acid-induced gene expression in colon cancer cells.
Carcinogenesis
2006
15507430
The adenovirus E4orf6 protein inhibits DNA double strand break repair and radiosensitizes human tumor cells in an E1B-55K-independent manner.
J Biol Chem
2005
3574053
Plasma beta-endorphin responses to one-hour bicycling and running at 60% VO2max.
Med Sci Sports Exerc
1987
1 - 31 of 31
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Korea University
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3
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Co-authored papers
3
Yael P Mosse
Perelman School of Medicine at the University of Pennsylvania
Co-authored papers
2
Komal S Rathi
Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia
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Alvin Farrel
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Co-authored papers
2
Javed Khan
Center for Cancer Research, National Cancer Institute
Co-authored papers
2
Jun S Wei
Center for Cancer Research, National Cancer Institute
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2
John Alan Diehl
Case Western Reserve University School of Medicine
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2
Joshua E Allen
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2
Daniela S Gerhard
National Cancer Institute
Co-authored papers
2
Kristina A Cole
Perelman School of Medicine, University of Pennsylvania
Co-authored papers
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Malcolm A Smith
National Cancer Institute
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Jaime M Guidry Auvil
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Julie M Gastier-Foster
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