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Author Details

Miguel A Valverde
Universitat Pompeu Fabra
1991
119
48
PMIDPaper TitleJournal TitlePublished Year
32959389Structural determinants of TRPV4 inhibition and identification of new antagonists with antiviral activity.Br J Pharmacol2022
36323783Extracellular fluid viscosity enhances cell migration and cancer dissemination.Nature2022
36253369Polarized NHE1 and SWELL1 regulate migration direction, efficiency and metastasis.Nat Commun2022
33399853Cross-talk between the calcium channel TRPV4 and reactive oxygen species interlocks adhesive and degradative functions of invadosomes.J Cell Biol2021
34714681The mechanosensitive Piezo1 channel controls endosome trafficking for an efficient cytokinetic abscission.Sci Adv2021
34244134The fluid shear stress sensor TRPM7 regulates tumor cell intravasation.Sci Adv2021
34083438LRRC8A-containing chloride channel is crucial for cell volume recovery and survival under hypertonic conditions.Proc Natl Acad Sci U S A2021
33060331The nucleus measures shape changes for cellular proprioception to control dynamic cell behavior.Science2020
30482841Sodium channel TRPM4 and sodium/calcium exchangers (NCX) cooperate in the control of Ca<sup>2+</sup>-induced mucin secretion from goblet cells.J Biol Chem2019
31355337Cell sensing and decision-making in confinement: The role of TRPM7 in a tug of war between hydraulic pressure and cross-sectional area.Sci Adv2019
29432180Piezo2 channel regulates RhoA and actin cytoskeleton to promote cell mechanobiological responses.Proc Natl Acad Sci U S A2018
29899501The TRPV4 channel links calcium influx to DDX3X activity and viral infectivity.Nat Commun2018
30108184Functional coupling of GABA<sub>A/B</sub> receptors and the channel TRPV4 mediates rapid progesterone signaling in the oviduct.Sci Signal2018
30272559KChIP3 coupled to Ca<sup>2+</sup> oscillations exerts a tonic brake on baseline mucin release in the colon.Elife2018
29742440DYRK1A Kinase Positively Regulates Angiogenic Responses in Endothelial Cells.Cell Rep2018
28874838Structural determinants of 5',6'-epoxyeicosatrienoic acid binding to and activation of TRPV4 channel.Sci Rep2017
28449493TRPV1 polymorphisms influence capsaicin cough sensitivity in men.J Thorac Dis2017
29057902TRPV4 activation triggers protective responses to bacterial lipopolysaccharides in airway epithelial cells.Nat Commun2017
29100528Silica nanoparticles inhibit the cation channel TRPV4 in airway epithelial cells.Part Fibre Toxicol2017
29245899Constitutive Cyclin O deficiency results in penetrant hydrocephalus, impaired growth and infertility.Oncotarget2017
26933123GEMC1 is a critical regulator of multiciliated cell differentiation.EMBO J2016
26673139TRPV4-Mediated Detection of Hyposmotic Stress by Skin Keratinocytes Activates Developmental Immunity.J Immunol2016
27557499Glutamatergic stimulation induces GluN2B translation by the nitric oxide-Heme-Regulated eIF2α kinase in cortical neurons.Oncotarget2016
27496898In vitro and in vivo evidence for an inflammatory role of the calcium channel TRPV4 in lung epithelium: Potential involvement in cystic fibrosis.Am J Physiol Lung Cell Mol Physiol2016
27160899Confinement Sensing and Signal Optimization via Piezo1/PKA and Myosin II Pathways.Cell Rep2016
27044636Correction: Cutting Edge: TRPV4-Mediated Detection of Hyposmotic Stress by Skin Keratinocytes Activates Developmental Immunity.J Immunol2016
25559845TRPV4 participates in the establishment of trailing adhesions and directional persistence of migrating cells.Pflugers Arch2015
26332322Endothelial Progenitor Cells Predict Cardiovascular Events after Atherothrombotic Stroke and Acute Myocardial Infarction. A PROCELL Substudy.PLoS One2015
26146187Interaction between the Linker, Pre-S1, and TRP Domains Determines Folding, Assembly, and Trafficking of TRPV Channels.Structure2015
25659150Tungstate-targeting of BKαβ1 channels tunes ERK phosphorylation and cell proliferation in human vascular smooth muscle.PLoS One2015
25619946Mobilization of endothelial progenitor cells in acute cardiovascular events in the PROCELL study: time-course after acute myocardial infarction and stroke.J Mol Cell Cardiol2015
25500153Fibrinogen nitrotyrosination after ischemic stroke impairs thrombolysis and promotes neuronal death.Biochim Biophys Acta2015
24158430BK channel activation by tungstate requires the β1 subunit extracellular loop residues essential to modulate voltage sensor function and channel gating.Pflugers Arch2014
24756711The TRPV4 channel.Handb Exp Pharmacol2014
24586184Extreme population differences in the human zinc transporter ZIP4 (SLC39A4) are explained by positive selection in Sub-Saharan Africa.PLoS Genet2014
24503620Posttranslational nitro-glycative modifications of albumin in Alzheimer's disease: implications in cytotoxicity and amyloid-β peptide aggregation.J Alzheimers Dis2014
24445160A loss-of-function CACNA1A mutation causing benign paroxysmal torticollis of infancy.Eur J Paediatr Neurol2014
23100328ORMDL3 modulates store-operated calcium entry and lymphocyte activation.Hum Mol Genet2013
24498617Screening of CACNA1A and ATP1A2 genes in hemiplegic migraine: clinical, genetic, and functional studies.Mol Genet Genomic Med2013
24069280Rare variants in calcium homeostasis modulator 1 (CALHM1) found in early onset Alzheimer's disease patients alter calcium homeostasis.PLoS One2013
23983901Nitro-oxidative stress after neuronal ischemia induces protein nitrotyrosination and cell death.Oxid Med Cell Longev2013
23690576Phosphatidylinositol-4,5-biphosphate-dependent rearrangement of TRPV4 cytosolic tails enables channel activation by physiological stimuli.Proc Natl Acad Sci U S A2013
23741618TRPM5-mediated calcium uptake regulates mucin secretion from human colon goblet cells.Elife2013
22473360Tungstate activates BK channels in a β subunit- and Mg2+-dependent manner: relevance for arterial vasodilatation.Cardiovasc Res2012
23266954Cab45 is required for Ca(2+)-dependent secretory cargo sorting at the trans-Golgi network.J Cell Biol2012
22443337Transient receptor potential genes, smoking, occupational exposures and cough in adults.Respir Res2012
21427121A gain-of-function SNP in TRPC4 cation channel protects against myocardial infarction.Cardiovasc Res2011
21799020Ion channels in asthma.J Biol Chem2011
21571222ADF/cofilin regulates secretory cargo sorting at the TGN via the Ca2+ ATPase SPCA1.Dev Cell2011
19819884The asthma-associated ORMDL3 gene product regulates endoplasmic reticulum-mediated calcium signaling and cellular stress.Hum Mol Genet2010
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Collaborators

Universitat Pompeu Fabra
Co-authored papers 24
Universitat Pompeu Fabra
Co-authored papers 11
Department of Medicine and Research Center, Montreal Heart Institute
Co-authored papers 10
Co-authored papers 6
Co-authored papers 6
Co-authored papers 3
Universitat Pompeu Fabra
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
Universitat Pompeu Fabra
Co-authored papers 1
Portland Alcohol Research Center, Oregon Health and Science University
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Oregon Health & Science University
Co-authored papers 1
The First Clinical Medical School of Shanxi Medical University
Co-authored papers 1
Biofuels Institute, Jiangsu University
Co-authored papers 1
Institute and Clinic for Occupational, University Hospital
Co-authored papers 1
Universitat Pompeu Fabra
Co-authored papers 1
Co-authored papers 1
Johns Hopkins University
Co-authored papers 1
Oregon Health & Science University, University of California Berkeley
Co-authored papers 1
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 1
Co-authored papers 1
Co-authored papers 1
Metabolism and Clinical Nutrition, Oregon Health and Sciences University.
Co-authored papers 1
Southern Plains Agricultural Research Center, USDA-ARS, College Station
Co-authored papers 1
Oregon Health and Science University
Co-authored papers 1
Sidra Medical Center
Co-authored papers 1
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University of Oxford
Co-authored papers 1