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Author Details

Natalia Issaeva
The University of North Carolina at Chapel Hill
2002
52
27
PMIDPaper TitleJournal TitlePublished Year
37523561Noncanonical HPV carcinogenesis drives radiosensitization of head and neck tumors.Proc Natl Acad Sci U S A2023
37523561Noncanonical HPV carcinogenesis drives radiosensitization of head and neck tumors.Proc Natl Acad Sci U S A2023
36164654Exploring ABOBEC3A and APOBEC3B substrate specificity and their role in HPV positive head and neck cancer.iScience2022
36248736Erratum: Exploring APOBEC3A and APOBEC3B substrate specificity and their role in HPV positive head and neck cancer.iScience2022
36164654Exploring ABOBEC3A and APOBEC3B substrate specificity and their role in HPV positive head and neck cancer.iScience2022
35634245NF-κB over-activation portends improved outcomes in HPV-associated head and neck cancer.Oncotarget2022
36074493Development of a Novel Molecular Test for Determining HPV Integration Status in HPV-Positive Oropharynx Cancers.JAMA Otolaryngol Head Neck Surg2022
36139648Direct Comparison of HPV16 Viral Genomic Integration, Copy Loss, and Structural Variants in Oropharyngeal and Uterine Cervical Cancers Reveal Distinct Relationships to E2 Disruption and Somatic Alteration.Cancers (Basel)2022
35731223Comprehensive Viral Genotyping Reveals Prognostic Viral Phylogenetic Groups in HPV16-Associated Squamous Cell Carcinoma of the Oropharynx.Mol Cancer Res2022
35720128Novel Allosteric Mechanism of Dual p53/MDM2 and p53/MDM4 Inhibition by a Small Molecule.Front Mol Biosci2022
35731223Comprehensive Viral Genotyping Reveals Prognostic Viral Phylogenetic Groups in HPV16-Associated Squamous Cell Carcinoma of the Oropharynx.Mol Cancer Res2022
35634245NF-κB over-activation portends improved outcomes in HPV-associated head and neck cancer.Oncotarget2022
35720128Novel Allosteric Mechanism of Dual p53/MDM2 and p53/MDM4 Inhibition by a Small Molecule.Front Mol Biosci2022
36248736Erratum: Exploring APOBEC3A and APOBEC3B substrate specificity and their role in HPV positive head and neck cancer.iScience2022
36074493Development of a Novel Molecular Test for Determining HPV Integration Status in HPV-Positive Oropharynx Cancers.JAMA Otolaryngol Head Neck Surg2022
36139648Direct Comparison of HPV16 Viral Genomic Integration, Copy Loss, and Structural Variants in Oropharyngeal and Uterine Cervical Cancers Reveal Distinct Relationships to E2 Disruption and Somatic Alteration.Cancers (Basel)2022
33994371Dual Targeting of Chromatin Stability By The Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Shows Significant Preclinical Efficacy in Neuroblastoma.Clin Cancer Res2021
33994371Dual Targeting of Chromatin Stability By The Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Shows Significant Preclinical Efficacy in Neuroblastoma.Clin Cancer Res2021
33819343Genomic heterogeneity and copy number variant burden are associated with poor recurrence-free survival and 11q loss in human papillomavirus-positive squamous cell carcinoma of the oropharynx.Cancer2021
33819343Genomic heterogeneity and copy number variant burden are associated with poor recurrence-free survival and 11q loss in human papillomavirus-positive squamous cell carcinoma of the oropharynx.Cancer2021
32793658EGFR in head and neck squamous cell carcinoma: exploring possibilities of novel drug combinations.Ann Transl Med2020
33374558Global Genome Demethylation Causes Transcription-Associated DNA Double Strand Breaks in HPV-Associated Head and Neck Cancer Cells.Cancers (Basel)2020
32793658EGFR in head and neck squamous cell carcinoma: exploring possibilities of novel drug combinations.Ann Transl Med2020
33374558Global Genome Demethylation Causes Transcription-Associated DNA Double Strand Breaks in HPV-Associated Head and Neck Cancer Cells.Cancers (Basel)2020
30647454APOBEC-induced mutations and their cancer effect size in head and neck squamous cell carcinoma.Oncogene2019
30647454APOBEC-induced mutations and their cancer effect size in head and neck squamous cell carcinoma.Oncogene2019
30755439Combined Aurora Kinase A (AURKA) and WEE1 Inhibition Demonstrates Synergistic Antitumor Effect in Squamous Cell Carcinoma of the Head and Neck.Clin Cancer Res2019
30857153p53 Signaling in Cancers.Cancers (Basel)2019
31321084NSD1 mutations by HPV status in head and neck cancer: differences in survival and response to DNA-damaging agents.Cancers Head Neck2019
31321084NSD1 mutations by HPV status in head and neck cancer: differences in survival and response to DNA-damaging agents.Cancers Head Neck2019
30857153p53 Signaling in Cancers.Cancers (Basel)2019
30755439Combined Aurora Kinase A (AURKA) and WEE1 Inhibition Demonstrates Synergistic Antitumor Effect in Squamous Cell Carcinoma of the Head and Neck.Clin Cancer Res2019
30380422Genomic and Transcriptomic Characterization Links Cell Lines with Aggressive Head and Neck Cancers.Cell Rep2018
29921694Attenuated TRAF3 Fosters Activation of Alternative NF-κB and Reduced Expression of Antiviral Interferon, TP53, and RB to Promote HPV-Positive Head and Neck Cancers.Cancer Res2018
30380422Genomic and Transcriptomic Characterization Links Cell Lines with Aggressive Head and Neck Cancers.Cell Rep2018
30035167Advances in biomarkers and treatment strategies for HPV-associated head and neck cancer.Oncoscience2018
31093365HPV-driven oropharyngeal cancer: current knowledge of molecular biology and mechanisms of carcinogenesis.Cancers Head Neck2018
30035167Advances in biomarkers and treatment strategies for HPV-associated head and neck cancer.Oncoscience2018
29921694Attenuated TRAF3 Fosters Activation of Alternative NF-κB and Reduced Expression of Antiviral Interferon, TP53, and RB to Promote HPV-Positive Head and Neck Cancers.Cancer Res2018
31093365HPV-driven oropharyngeal cancer: current knowledge of molecular biology and mechanisms of carcinogenesis.Cancers Head Neck2018
28027003LZAP is a novel Wip1 binding partner and positive regulator of its phosphatase activity in vitro.Cell Cycle2017
28916527Demethylation Therapy as a Targeted Treatment for Human Papillomavirus-Associated Head and Neck Cancer.Clin Cancer Res2017
28394357Loss of LZAP inactivates p53 and regulates sensitivity of cells to DNA damage in a p53-dependent manner.Oncogenesis2017
29196570Reactivation of mutant p53 and induction of apoptosis in human tumor cells by maleimide analogs.J Biol Chem2017
28027003LZAP is a novel Wip1 binding partner and positive regulator of its phosphatase activity in vitro.Cell Cycle2017
28295222TRAF3/CYLD mutations identify a distinct subset of human papillomavirus-associated head and neck squamous cell carcinoma.Cancer2017
28295222TRAF3/CYLD mutations identify a distinct subset of human papillomavirus-associated head and neck squamous cell carcinoma.Cancer2017
28394357Loss of LZAP inactivates p53 and regulates sensitivity of cells to DNA damage in a p53-dependent manner.Oncogenesis2017
29196570Reactivation of mutant p53 and induction of apoptosis in human tumor cells by maleimide analogs.J Biol Chem2017
28916527Demethylation Therapy as a Targeted Treatment for Human Papillomavirus-Associated Head and Neck Cancer.Clin Cancer Res2017
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Collaborators

Wendell G Yarbrough
University of North Carolina at Chapel Hill
Co-authored papers 26
Thomas Helleday
The University of Sheffield
Co-authored papers 7
Adel K El-Naggar
MD Anderson Cancer Center
Co-authored papers 2
Michelle Haber
School of Clinical Medicine
Co-authored papers 2
Carter Van Waes
National Institute of Deafness and Other Communication Disorders
Co-authored papers 2
Martin Enge
Karolinska Institutet
Co-authored papers 2
David S Ziegler
Co-authored papers 2
Glenn M Marshall
Children's Cancer Institute, Lowy Cancer Research Centre
Co-authored papers 2
Xinping Yang
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Co-authored papers 2
Zhong Chen
National Institute on Deafness and Other Communication Disorders
Co-authored papers 2
Jennifer R Grandis
University of California san francisco
Co-authored papers 2
Gordon B Mills
Knight Cancer Institute, Oregon Health and Sciences University
Co-authored papers 2
Michelle J Henderson
Children's Cancer Institute, Lowy Cancer Research Centre
Co-authored papers 1
Xingzhi Song
The University of Texas MD Anderson Cancer Center
Co-authored papers 1
Joel S Parker
Lineberger Cancer Center, University of North Carolina
Co-authored papers 1
Sahil Seth
The University of Texas MD Anderson Cancer Center
Co-authored papers 1
Jong Woo Lee
Brigham and Women's Hospital
Co-authored papers 1
Jamie I Fletcher
Co-authored papers 1
Netty Santoso
The Ohio State University Wexner Medical Center
Co-authored papers 1
Erica A Golemis
Co-authored papers 1
Raju Kucherlapati
Harvard Medical School
Co-authored papers 1
Olga Loseva
Karolinska Institutet
Co-authored papers 1
Jiabin Tang
The University of MD Anderson Cancer Center
Co-authored papers 1
Michael Parfenov
Harvard Medical School, Brigham and Women's Hospital
Co-authored papers 1
Ludmila Danilova
Bloomberg-Kimmel Immunotherapy Institute, Johns Hopkins University School of Medicine
Co-authored papers 1
Thomas E Carey
Kresge Hearing Research Institute, University of Michigan ann arbor
Co-authored papers 1
Peter S Hammerman
Novartis Institutes for BioMedical Research
Co-authored papers 1
Joonil Jung
Broad Institute of MIT and Harvard
Co-authored papers 1
Chandra Sekhar Pedamallu
Broad Institute
Co-authored papers 1
David Neil Hayes
Center for Cancer Research, University of Tennessee Health Science Center
Co-authored papers 1
Release 1.2