Author details

Full Name

FranÃ§oise Clerget-Darpoux

Affiliation

ORCID

Career Start Year

1978

Papers

181

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
35092541	Heritability: What's the point? What is it not for? A human genetics perspective.	Genetica	2022
36013215	The False Dawn of Polygenic Risk Scores for Human Disease Prediction.	Journal of Personalized Medicine	2022
27576757	Revisiting the Polygenic Additive Liability Model through the Example of Diabetes Mellitus.	Human Heredity	2015
25660130	The missing heritability paradigm: a dramatic resurgence of the GIGO syndrome in genetics.	Human Heredity	2015
25642776	Functional variants of POC5 identified in patients with idiopathic scoliosis.	J Clin Invest	2015
26166481	Mutations in KIAA0586 Cause Lethal Ciliopathies Ranging from a Hydrolethalus Phenotype to Short-Rib Polydactyly Syndrome.	Am J Hum Genet	2015
23671607	Chromosome 21 scan in Down syndrome reveals DSCAM as a predisposing locus in Hirschsprung disease.	PLoS One	2013
24107572	Will formal genetics become dispensable?	Human Heredity	2013
22085902	Determination of the real effect of genes identified in GWAS: the example of IL2RA in multiple sclerosis.	Eur J Hum Genet	2012
22395866	Male and female differential reproductive rate could explain parental transmission asymmetry of mutation origin in Hirschsprung disease.	Eur J Hum Genet	2012
22377294	[Extreme microcephaly and growth retardation caused by mutations in a non-coding RNA component of the minor spliceosome].	Medecine/Sciences	2012
23594491	Using affected sib-pairs to uncover rare disease variants.	Hum Hered	2012
21833088	Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.	Nature	2011
21474761	Association of TALS developmental disorder with defect in minor splicing component U4atac snRNA.	Science	2011
21153621	Modeling the effect of susceptibility factors (HLA and PTPN22) in rheumatoid arthritis.	Methods in Molecular Biology	2011
21407261	New disease gene location and high genetic heterogeneity in idiopathic scoliosis.	European Journal of Human Genetics	2011
19156166	IFIH1-GCA-KCNH7 locus is not associated with genetic susceptibility to multiple sclerosis in French patients.	European Journal of Human Genetics	2009
19548341	The ordered transmission disequilibrium test: detection of modifier genes.	Genetic Epidemiology	2009
18354419	IL2RA and IL7RA genes confer susceptibility for multiple sclerosis in two independent European populations.	Genes Immun	2008
18615093	HLA-DRB1*15 allele influences the later course of relapsing remitting multiple sclerosis.	Genes Immun	2008
18562513	No evidence for association between the EIF2B5 gene and multiple sclerosis in French families.	Multiple Sclerosis Journal	2008
18784943	Identifying modifier genes of monogenic disease: strategies and difficulties.	Human Genetics	2008
18466442	On the choice of linkage statistics.	BMC Proceedings	2007
17476108	Are linkage analysis and the collection of family data dead? Prospects for family studies in the age of genome-wide association.	Human Heredity	2007
17283437	Strategy for detecting susceptibility genes with weak or no marginal effect.	Hum Hered	2007
17607189	[What's new in multiple sclerosis genetics?].	Revue Neurologique	2007
17164797	Are genome-wide association studies all that we need to dissect the genetic component of complex human diseases?	Eur J Hum Genet	2007
17508359	Power of genome-wide association studies in the presence of interacting loci.	Genet Epidemiol	2007
17344279	HLA related genetic risk for coeliac disease.	Gut	2007
18046759	Discussing gene-gene interaction: warning--translating equations to English may result in jabberwocky.	Genet Epidemiol	2007
18046758	Using linkage and association to identify and model genetic effects: summary of GAW15 Group 4.	Genet Epidemiol	2007
18466579	An ordered subset approach to including covariates in the transmission disequilibrium test.	BMC Proc	2007
18466566	Power of the 2-locus TDT for testing the interaction of two susceptibility genes.	BMC Proc	2007
18466535	Modeling the effect of PTPN22 in rheumatoid arthritis.	BMC Proc	2007
16773566	Using genomic inbreeding coefficient estimates for homozygosity mapping of rare recessive traits: application to Taybi-Linder syndrome.	American Journal of Human Genetics	2006
16943798	A family-based study does not confirm the association of MYO9B with celiac disease in the Italian population.	Genes and Immunity	2006
16646982	Validation of the reshaped shared epitope HLA-DRB1 classification in rheumatoid arthritis.		2006
16451626	Detection of susceptibility loci by genome-wide linkage analysis.	BMC Genetics	2005
15818663	New classification of HLA-DRB1 alleles supports the shared epitope hypothesis of rheumatoid arthritis susceptibility.		2005
15904815	[Genetic epidemiology of celiac disease].	Archives de Pediatrie	2005
15889046	Allele variations in the OCA2 gene (pink-eyed-dilution locus) are associated with genetic susceptibility to melanoma.	European Journal of Human Genetics	2005
16451702	Modeling the effect of a genetic factor for a complex trait in a simulated population.	BMC Genet	2005
14989710	Candidate gene region 2q33 in European families with coeliac disease.		2004
15711087	Association in multifactorial traits: how to deal with rare observations?	Human Heredity	2004
15140032	HLA-DQ relative risks for coeliac disease in European populations: a study of the European Genetics Cluster on Coeliac Disease.	Tissue Antigens	2004
14595552	Investigation of seven proposed regions of linkage in multiple sclerosis: an American and French collaborative study.	Neurogenetics	2004
14627687	Genetic study of transthyretin amyloid neuropathies: carrier risks among French and Portuguese families.	Journal of Medical Genetics	2003
14551606	Intercellular adhesion molecule-1: a protective haplotype against multiple sclerosis.	Genes and Immunity	2003
12916024	Improved use of SNP information to detect the role of genes.	Genet Epidemiol	2003
12914578	Saturation of the 5q31-q33 candidate region for coeliac disease.	Annals of Human Genetics	2003