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Author Details

R D Andrew
Queen's University
1978
75
36
PMIDPaper TitleJournal TitlePublished Year
37471497Validating MALDI-IMS Feasibility in <i>Ex Vivo</i> Brain Slices.J Am Soc Mass Spectrom2023
35194729Questioning Glutamate Excitotoxicity in Acute Brain Damage: The Importance of Spreading Depolarization.Neurocrit Care2022
35257321The Critical Role of Spreading Depolarizations in Early Brain Injury: Consensus and Contention.Neurocrit Care2022
33459722Age-Related Neuronal Deterioration Specifically Within the Dorsal CA1 Region of the Hippocampus in a Mouse Model of Late Onset Alzheimer's Disease.J Alzheimers Dis2021
34498208Neuronal Swelling: A Non-osmotic Consequence of Spreading Depolarization.Neurocrit Care2021
31388871Which Spreading Depolarizations Are Deleterious To Brain Tissue?Neurocrit Care2020
32023142Neural shutdown under stress: an evolutionary perspective on spreading depolarization.J Neurophysiol2020
32925058Neuronal Calcium Imaging, Excitability, and Plasticity Changes in the Aldh2-/- Mouse Model of Sporadic Alzheimer's Disease.J Alzheimers Dis2020
32144984Morphometric Analysis of Hippocampal and Neocortical Pyramidal Neurons in a Mouse Model of Late Onset Alzheimer's Disease.J Alzheimers Dis2020
30811255Spreading depolarization and neuronal damage or survival in mouse neocortical brain slices immediately and 12 hours following middle cerebral artery occlusion.J Neurophysiol2019
29802597Developmental origins of pregnancy-induced cardiac changes: establishment of a novel model using the atrial natriuretic peptide gene-disrupted mice.Mol Cell Biochem2018
27317657Recording, analysis, and interpretation of spreading depolarizations in neurointensive care: Review and recommendations of the COSBID research group.J Cereb Blood Flow Metab2017
27328690The continuum of spreading depolarizations in acute cortical lesion development: Examining Leão's legacy.J Cereb Blood Flow Metab2017
27381828Spreading depolarization triggered by elevated potassium is weak or absent in the rodent lower brain.J Cereb Blood Flow Metab2017
26852334Large extracellular space leads to neuronal susceptibility to ischemic injury in a Na+/K+ pumps-dependent manner.J Comput Neurosci2016
27334953Mechanisms of spreading depolarization in vertebrate and insect central nervous systems.J Neurophysiol2016
25391363Molecular adaptations in vasoactive systems during acute stroke in salt-induced hypertension.Mol Cell Biochem2015
26536903Onset and Regression of Pregnancy-Induced Cardiac Alterations in Gestationally Hypertensive Mice: The Role of the Natriuretic Peptide System.Biol Reprod2015
26169981Maternal hypertension programs increased cerebral tissue damage following stroke in adult offspring.Mol Cell Biochem2015
25910195Characterization of Aldh2 (-/-) mice as an age-related model of cognitive impairment and Alzheimer's disease.Mol Brain2015
24802253Brainstem neurons survive the identical ischemic stress that kills higher neurons: insight to the persistent vegetative state.PLoS One2014
24223181A distinct boundary between the higher brain's susceptibility to ischemia and the lower brain's resistance.PLoS One2013
22279188Examining protection from anoxic depolarization by the drugs dibucaine and carbetapentane using whole cell recording from CA1 neurons.J Neurophysiol2012
22514289A neuronal population in hypothalamus that dramatically resists acute ischemic injury compared to neocortex.J Neurophysiol2012
21273307Potent inhibition of anoxic depolarization by the sodium channel blocker dibucaine.J Neurophysiol2011
18720409Real-time passive volume responses of astrocytes to acute osmotic and ischemic stress in cortical slices and in vivo revealed by two-photon microscopy.Glia2009
17942540Structural abnormalities in neurons are sufficient to explain the clinical disease and fatal outcome of experimental rabies in yellow fluorescent protein-expressing transgenic mice.J Virol2008
18728492Perivascular aquaporins: potential postischemic therapeutic drug targets?Crit Care Med2008
18383299Magnetic resonance imaging of neuronal and glial swelling as an indicator of function in cerebral tissue slices.Magn Reson Med2008
16723408Physiological evidence that pyramidal neurons lack functional water channels.Cereb Cortex2007
17765319Whole isolated neocortical and hippocampal preparations and their use in imaging studies.J Neurosci Methods2007
15456803Blocking the anoxic depolarization protects without functional compromise following simulated stroke in cortical brain slices.J Neurophysiol2005
15716633Spreading depression expands traumatic injury in neocortical brain slices.J Neurotrauma2005
12654976Elevated polyunsaturated fatty acids in blood serum obtained from children on the ketogenic diet.Neurology2003
12424306Spreading depression: imaging and blockade in the rat neocortical brain slice.J Neurophysiol2002
11152742Imaging anoxic depolarization during ischemia-like conditions in the mouse hemi-brain slice.J Neurophysiol2001
11230096Anoxic depolarization mediates acute damage independent of glutamate in neocortical brain slices.Cereb Cortex2001
10734167ATP inhibits glutamate synaptic release by acting at P2Y receptors in pyramidal neurons of hippocampal slices.J Pharmacol Exp Ther2000
11121525Interferon-alpha inhibits long-term potentiation and unmasks a long-term depression in the rat hippocampus.Brain Res2000
10698080Glutamate does not mediate acute neuronal damage after spreading depression induced by O2/glucose deprivation in the hippocampal slice.J Cereb Blood Flow Metab2000
10493895Interpretation of intrinsic optical signals and calcein fluorescence during acute excitotoxic insult in the hippocampal slice.Neuroimage1999
10356350Potential sources of intrinsic optical signals imaged in live brain slices.Methods1999
9824458Spreading depression determines acute cellular damage in the hippocampal slice during oxygen/glucose deprivation.Eur J Neurosci1998
9666481Intrinsic optical signaling denoting neuronal damage in response to acute excitotoxic insult by domoic acid in the hippocampal slice.Neurobiol Dis1998
9736642Imaging spreading depression and associated intracellular calcium waves in brain slices.J Neurosci1998
9056392Evidence against volume regulation by cortical brain cells during acute osmotic stress.Exp Neurol1997
8899640Imaging NMDA- and kainate-induced intrinsic optical signals from the hippocampal slice.J Neurophysiol1996
8909784Real-time imaging of intrinsic optical signals during early excitotoxicity evoked by domoic acid in the rat hippocampal slice.Can J Physiol Pharmacol1996
8624714Effects of micromolar and nanomolar calcium concentrations on non-synaptic bursting in the hippocampal slice.Brain Res1995
8747780Time-dependent decreases of atrial natriuretic peptide release from the isolated rat atrium: evidence for a readily releasable pool.Regul Pept1995
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Collaborators

Medical College of Georgia at Augusta University
Co-authored papers 9
Djavad Mowafaghian Center for Brain Health, University of British Columbia
Co-authored papers 6
University of Utah School of Medicine
Co-authored papers 5
Hungarian Centre of Excellence for Molecular Medicine-University of Szeged
Co-authored papers 5
Neurovascular Research Unit, Massachusetts General Hospital, Harvard Medical School
Co-authored papers 5
Queen's University
Co-authored papers 5
University of Cincinnati
Co-authored papers 5
Center for Stroke Research Berlin, Charite University
Co-authored papers 5
Cajal Institute-CSIC
Co-authored papers 3
Imperial College London
Co-authored papers 3
University of Cincinnati
Co-authored papers 3
Copenhagen University Hospital - Rigshospitalet
Co-authored papers 3
Medical University of Innsbruck
Co-authored papers 3
University of New Mexico School of Medicine
Co-authored papers 3
Beth Israel Deaconess Medical Center, Division of Neurocritical Care and Emergency Neurology, Division of Clinical Neurophysiology, Massachusetts General Hospital, Boston, MA, Harvard Medical School, Massachusetts General Hospital, Massachusetts General Hospital Fellowship in Epilepsy and Clinical Neurophysiology, Massachusetts General Hospital, Brigham and Women's Hospital, Harvard Medical School Fellowship Training Program in Neurocritical Care, Massachusetts General Hospital, Brigham and Women's Hospital, Harvard Medical School Partners Neurology Residency Training Program, Yale College
Co-authored papers 3
Center for Stroke Research Berlin
Co-authored papers 3
University of New Mexico
Co-authored papers 3
Heidelberg University Hospital, Ruprecht Karls University of Heidelberg
Co-authored papers 2
Robert Koch Institute
Co-authored papers 2
Heidelberg University Hospital, Ruprecht Karls University of Heidelberg
Co-authored papers 2
Interuniversity Microelectronics Centre
Co-authored papers 2
1 Center for Stroke Research Berlin, Charite University Medicine Berlin
Co-authored papers 2
Jena University Hospital - Friedrich Schiller University of Jena
Co-authored papers 2
University of Gothenburg
Co-authored papers 2
Vagalume LLC
Co-authored papers 2
Max-Planck-Institute for Neurological Research
Co-authored papers 2
Rigshospitalet, University of Copenhagen
Co-authored papers 2
Department of Basic and Clinical Neuroscience, King's College London
Co-authored papers 2
Imperial College London
Co-authored papers 2
University of Pittsburgh Medical Center
Co-authored papers 2