Author details

Full Name

Christian R H Raetz

Affiliation

ORCID

Career Start Year

1972

Papers

317

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37782650	Structure and Function of ArnD. A Deformylase Essential for Lipid A Modification with 4-Amino-4-deoxy-l-arabinose and Polymyxin Resistance.		2023
30850651	Structure guided design of an antibacterial peptide that targets UDP-N-acetylglucosamine acyltransferase.	Scientific Reports	2019
30092253	Biochemical and Structural Insights into an Fe(II)/Î±-Ketoglutarate/O-Dependent Dioxygenase, Kdo 3-Hydroxylase (KdoO).	Journal of Molecular Biology	2018
25204504	Kdo hydroxylase is an inner core assembly enzyme in the Ko-containing lipopolysaccharide biosynthesis.	Biochem Biophys Res Commun	2014
24196711	Chasing acyl carrier protein through a catalytic cycle of lipid A production.	Nature	2014
24479701	In vitro assembly of the outer core of the lipopolysaccharide from Escherichia coli K-12 and Salmonella typhimurium.	Biochemistry	2014
23413030	The origin of 8-amino-3,8-dideoxy-D-manno-octulosonic acid (Kdo8N) in the lipopolysaccharide of Shewanella oneidensis.	Journal of Biological Chemistry	2013
24189069	25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages.	J Biol Chem	2013
24046865	The calcium-stimulated lipid A 3-O deacylase from Rhizobium etli is not essential for plant nodulation.		2013
23357387	Pathogenicity of Yersinia pestis synthesis of 1-dephosphorylated lipid A.	Infection and Immunity	2013
23316051	Mutants resistant to LpxC inhibitors by rebalancing cellular homeostasis.	J Biol Chem	2013
23464738	Mechanistic characterization of the tetraacyldisaccharide-1-phosphate 4'-kinase LpxK involved in lipid A biosynthesis.	Biochemistry	2013
23659637	Complex transcriptional and post-transcriptional regulation of an enzyme for lipopolysaccharide modification.	Molecular Microbiology	2013
22215738	Role of Francisella lipid A phosphate modification in virulence and long-term protective immune responses.	Infection and Immunity	2012
22753374	Phosphate groups of lipid A are essential for Salmonella enterica serovar Typhimurium virulence and affect innate and adaptive immunity.	Infection and Immunity	2012
22554681	Density gradient enrichment of Escherichia coli lpxL mutants.		2012
22304929	Life with too much polyprenol: polyprenol reductase deficiency.	Mol Genet Metab	2012
22966934	NaxD is a deacetylase required for lipid A modification and Francisella pathogenesis.	Molecular Microbiology	2012
22586119	LPS remodeling is an evolved survival strategy for bacteria.	Proc Natl Acad Sci U S A	2012
22545860	Activity and crystal structure of Arabidopsis thaliana UDP-N-acetylglucosamine acyltransferase.	Biochemistry	2012
22837302	Lipid diversity among botulinum neurotoxin-producing clostridia.	Microbiology (Reading)	2012
22826246	Crystal structure of LpxK, the 4'-kinase of lipid A biosynthesis and atypical P-loop kinase functioning at the membrane interface.	Proceedings of the National Academy of Sciences of the United States of America	2012
22988102	Discovery of a cardiolipin synthase utilizing phosphatidylethanolamine and phosphatidylglycerol as substrates.	Proc Natl Acad Sci U S A	2012
23021221	Regulated accumulation of desmosterol integrates macrophage lipid metabolism and inflammatory responses.	Cell	2012
23042606	LpxI structures reveal how a lipid A precursor is synthesized.	Nat Struct Mol Biol	2012
23583844	The calcium-stimulated lipid A 3-O deacylase from Rhizobium etli is not essential for plant nodulation.		2012
21900247	Identification of self-lipids presented by CD1c and CD1d proteins.	J Biol Chem	2011
21167751	Species-specific and inhibitor-dependent conformations of LpxC: implications for antibiotic design.		2011
21195206	Structural characterization of the polar lipids of Clostridium novyi NT. Further evidence for a novel anaerobic biosynthetic pathway to plasmalogens.	Biochim Biophys Acta	2011
21194954	Syntheses, structures and antibiotic activities of LpxC inhibitors based on the diacetylene scaffold.	Bioorganic and Medicinal Chemistry	2011
21148555	Three phosphatidylglycerol-phosphate phosphatases in the inner membrane of Escherichia coli.	J Biol Chem	2011
21320544	A live attenuated strain of Yersinia pestis KIM as a vaccine against plague.	Vaccine	2011
21178073	Dioxygenases in Burkholderia ambifaria and Yersinia pestis that hydroxylate the outer Kdo unit of lipopolysaccharide.	Proceedings of the National Academy of Sciences of the United States of America	2011
21050835	Identification of a chloroform-soluble membrane miniprotein in Escherichia coli and its homolog in Salmonella typhimurium.	Anal Biochem	2011
21930761	Palmitoylation state impacts induction of innate and acquired immunity by the Salmonella enterica serovar typhimurium msbB mutant.	Infection and Immunity	2011
21632711	Salmonella synthesizing 1-dephosphorylated [corrected] lipopolysaccharide exhibits low endotoxic activity while retaining its immunogenicity.	Journal of Immunology	2011
21628561	Lipooligosaccharide is required for the generation of infectious elementary bodies in Chlamydia trachomatis.	Proc Natl Acad Sci U S A	2011
21925285	Non-enzymatically derived minor lipids found in Escherichia coli lipid extracts.	Biochim Biophys Acta	2011
21709257	Pathway for lipid A biosynthesis in Arabidopsis thaliana resembling that of Escherichia coli.	Proc Natl Acad Sci U S A	2011
21641550	Mitochondrial phosphatase PTPMT1 is essential for cardiolipin biosynthesis.	Cell Metab	2011
20671299	Lipidomics reveals a remarkable diversity of lipids in human plasma.	J Lipid Res	2010
20802039	AglJ adds the first sugar of the N-linked pentasaccharide decorating the Haloferax volcanii S-layer glycoprotein.	J Bacteriol	2010
20795687	Escherichia coli mutants that synthesize dephosphorylated lipid A molecules.	Biochemistry	2010
20685834	Expression of functional bacterial undecaprenyl pyrophosphate synthase in the yeast rer2{Delta} mutant and CHO cells.	Glycobiology	2010
20681981	Distinct granuloma responses in C57BL/6J and BALB/cByJ mice in response to pristane.	Int J Exp Pathol	2010
20923771	A mouse macrophage lipidome.	J Biol Chem	2010
20574076	Subcellular organelle lipidomics in TLR-4-activated macrophages.	J Lipid Res	2010
20394418	Interchangeable domains in the Kdo transferases of Escherichia coli and Haemophilus influenzae.	Biochemistry	2010
19941092	Assignment of 1H, 13C and 15N backbone resonances of Escherichia coli LpxC bound to L-161,240.	Biomolecular NMR Assignments	2010
20173213	A phosphoethanolamine-modified glycosyl diradylglycerol in the polar lipids of Clostridium tetani.	J Lipid Res	2010