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Author Details

Nidhi Sahni
The University of Texas MD Anderson Cancer Center
2008
64
30
Gloria M Sheynkman (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36265133Landscape of MicroRNA Regulatory Network Architecture and Functional Rerouting in Cancer.Cancer Res2023
37909041Widespread BRCA1/2-independent homologous recombination defects are caused by alterations in RNA-binding proteins.Cell Rep Med2023
37540752Multiomics analyses reveal <i>DARS1-AS1</i>/YBX1-controlled posttranscriptional circuits promoting glioblastoma tumorigenesis/radioresistance.Sci Adv2023
37732209Pervasive mislocalization of pathogenic coding variants underlying human disorders.bioRxiv2023
37770423Defining the condensate landscape of fusion oncoproteins.Nat Commun2023
37191809Gain-of-Function Variomics and Multi-omics Network Biology for Precision Medicine.Methods Mol Biol2023
37115914Alternative splicing of <i>GSDMB</i> modulates killer lymphocyte-triggered pyroptosis.Sci Immunol2023
36752347AD-Syn-Net: systematic identification of Alzheimer's disease-associated mutation and co-mutation vulnerabilities via deep learning.Brief Bioinform2023
36879885AI-DrugNet: A network-based deep learning model for drug repurposing and combination therapy in neurological disorders.Comput Struct Biotechnol J2023
36631436The HAPSTR2 retrogene buffers stress signaling and resilience in mammals.Nat Commun2023
35138907A functional genomic approach to actionable gene fusions for precision oncology.Sci Adv2022
35492246A network-based approach to identify expression modules underlying rejection in pediatric liver transplantation.Cell Rep Med2022
35852417Biomolecular Condensation: A New Phase in Cancer Research.Cancer Discov2022
35860408i-Modern: Integrated multi-omics network model identifies potential therapeutic targets in glioma by deep learning with interpretability.Comput Struct Biotechnol J2022
36518525Single-cell CRISPR immune screens reveal immunological roles of tumor intrinsic factors.NAR Cancer2022
33211847e-MutPath: computational modeling reveals the functional landscape of genetic mutations rewiring interactome networks.Nucleic Acids Res2021
33855356mi-IsoNet: systems-scale microRNA landscape reveals rampant isoform-mediated gain of target interaction diversity and signaling specificity.Brief Bioinform2021
29738884Pathway perturbations in signaling networks: Linking genotype to phenotype.Semin Cell Dev Biol2020
32855206Integrated Genomic Characterization of the Human Immunome in Cancer.Cancer Res2020
32358509PBRM1 loss defines a nonimmunogenic tumor phenotype associated with checkpoint inhibitor resistance in renal carcinoma.Nat Commun2020
32109374Proteome Instability Is a Therapeutic Vulnerability in Mismatch Repair-Deficient Cancer.Cancer Cell2020
32286303Cellular origins and genetic landscape of cutaneous gamma delta T cell lymphomas.Nat Commun2020
31185210Sequential Therapy with PARP and WEE1 Inhibitors Minimizes Toxicity while Maintaining Efficacy.Cancer Cell2019
30153342MERIT: Systematic Analysis and Characterization of Mutational Effect on RNA Interactome Topology.Hepatology2019
29325141LncMAP: Pan-cancer atlas of long noncoding RNA-mediated transcriptional network perturbations.Nucleic Acids Res2018
30102398FACER: comprehensive molecular and functional characterization of epigenetic chromatin regulators.Nucleic Acids Res2018
29941230Gene Regulatory Network Perturbation by Genetic and Epigenetic Variation.Trends Biochem Sci2018
30389923Neomorphic PDGFRA extracellular domain driver mutations are resistant to PDGFRA targeted therapies.Nat Commun2018
29615613Multi-omics analysis reveals neoantigen-independent immune cell infiltration in copy-number driven cancers.Nat Commun2018
29533785Systematic Functional Annotation of Somatic Mutations in Cancer.Cancer Cell2018
29045845Revealing the Determinants of Widespread Alternative Splicing Perturbation in Cancer.Cell Rep2017
28131823In Situ Peroxidase Labeling and Mass-Spectrometry Connects Alpha-Synuclein Directly to Endocytic Trafficking and mRNA Metabolism in Neurons.Cell Syst2017
28215707HSP90 Shapes the Consequences of Human Genetic Variation.Cell2017
28422313Regulome networks and mutational landscape in liver cancer: An informative path to precision medicine.Hepatology2017
28344341Functional variomics and network perturbation: connecting genotype to phenotype in cancer.Nat Rev Genet2017
28981122Base-resolution stratification of cancer mutations using functional variomics.Nat Protoc2017
26871637Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.Cell2016
27791983Comparative analysis of protein interactome networks prioritizes candidate genes with cancer signatures.Oncotarget2016
27525280Signal Transduction and Regulation: Insights into Evolution.Biomed Res Int2016
27403431Multi-OMICs and Genome Editing Perspectives on Liver Cancer Signaling Networks.Biomed Res Int2016
27013732Survey of variation in human transcription factors reveals prevalent DNA binding changes.Science2016
27107012Pooled-matrix protein interaction screens using Barcode Fusion Genetics.Mol Syst Biol2016
26975778An extended set of yeast-based functional assays accurately identifies human disease mutations.Genome Res2016
25586491A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma.Hum Mol Genet2015
27136053Global Edgetic Rewiring in Cancer Networks.Cell Syst2015
25910212Widespread macromolecular interaction perturbations in human genetic disorders.Cell2015
25910213Human gene-centered transcription factor networks for enhancers and disease variants.Cell2015
24623722Systematic identification of pathological lamin A interactors.Mol Biol Cell2014
25416956A proteome-scale map of the human interactome network.Cell2014
25184681Systematic screening reveals a role for BRCA1 in the response to transcription-associated DNA damage.Genes Dev2014
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Collaborators

Song Yi
Livestrong Cancer Institutes, Dell Medical School, The University of Texas at Austin
Co-authored papers 37
Daniel J McGrail
Center for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic
Co-authored papers 16
Gordon B Mills
Knight Cancer Institute, Oregon Health and Sciences University
Co-authored papers 14
Marc Vidal
Blavatnik Institute, Harvard Medical School
Co-authored papers 14
Yongsheng Li
Harbin Medical University
Co-authored papers 14
Shiaw-Yih Lin
The University of Texas MD Anderson Cancer Center
Co-authored papers 7
Erxi Wu
Livestrong Cancer Institutes, Dell Medical School, The University of Texas at Austin
Co-authored papers 6
Juan Xu
College of Bioinformatics Science and Technology, Harbin Medical University
Co-authored papers 5
Frederick P Roth
University of Toronto
Co-authored papers 5
Jasmin Coulombe-Huntington
Institute for Research in Immunology and Cancer, Universite de Montreal
Co-authored papers 4
Yiling Lu
Co-authored papers 4
Yu Xia
College of Information Engineering, Zhejiang University of Technology
Co-authored papers 3
Patrick Kwok-Shing Ng
The University of Texas MD Anderson Cancer Center
Co-authored papers 3
Limei Hu
Aier Eye Hospital of Wuhan University
Co-authored papers 3
Patrick Aloy
Institucio Catalana de Recerca i Estudis Avancats (ICREA)
Co-authored papers 3
Albert-L??szl?? Barab??si
Network Science Institute, Northeastern University
Co-authored papers 3
Gloria M Sheynkman (CM4AI)
University of Virginia
Co-authored papers 3
Jason H Huang
Baylor Scott and White Health and Texas A&M University College of Medicine
Co-authored papers 3
Susan Lindquist
Whitehead Institute for Biomedical Research
Co-authored papers 3
Zhenlin Ju
Co-authored papers 3
Zeynep Coban Akdemir
Baylor College of Medicine
Co-authored papers 3
Xiaoqian Jiang
Carnegie Mellon University, The University of Texas Health Science Center at Houston, University of California San Diego
Co-authored papers 3
Ken Chen
University of Texas MD Anderson Cancer Center
Co-authored papers 3
Luke Whitesell
University of Toronto
Co-authored papers 2
J??rg Menche
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Co-authored papers 2
Nozomu Yachie
The University of British Columbia
Co-authored papers 2
Brenda J Andrews
University of Toronto
Co-authored papers 2
Han Liang
MD Anderson Cancer Center
Co-authored papers 2
Li Guo
Co-authored papers 2
Charles Boone
University of Toronto
Co-authored papers 2
Release 1.2