Author details

Full Name

Karl Herrup

Affiliation

ORCID

Career Start Year

1973

Papers

201

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37546935	Cuprizone drives divergent neuropathological changes in different mouse models of Alzheimer's disease.		2023
36717226	The Amyloid Precursor Protein Modulates the Position and Length of the Axon Initial Segment.		2023
37334596	The Anti-Amyloid Monoclonal Antibody Lecanemab: 16 Cautionary Notes.		2023
36549843	Apolipoprotein E Îµ4 disrupts oligodendrocyte differentiation by interfering with astrocyte-derived lipid transport.		2023
36796939	Finding the falsification threshold of the toxic proteinopathy hypothesis in neurodegeneration.		2023
36849558	A neurodevelopmental epigenetic programme mediated by SMARCD3-DAB1-Reelin signalling is hijacked to promote medulloblastoma metastasis.	Nat Cell Biol	2023
35144999	Fallacies in Neuroscience: The Alzheimer's Edition.	eNeuro	2022
36197130	An Ethical Argument for Ending Human Trials of Amyloid-Lowering Therapies in Alzheimer's Disease.	AJOB Neuroscience	2022
35779013	Apolipoprotein E Îµ4 Mediates Myelin Breakdown by Targeting Oligodendrocytes in Sporadic Alzheimer Disease.	Journal of Neuropathology and Experimental Neurology	2022
34991436	Optimized splitting of mixed-species RNA sequencing data.	Journal of Bioinformatics and Computational Biology	2022
34593604	DNA Repair Inhibition Leads to Active Export of Repetitive Sequences to the Cytoplasm Triggering an Inflammatory Response.	Journal of Neuroscience	2021
33483322	Identifying a Population of Glial Progenitors That Have Been Mistaken for Neurons in Embryonic Mouse Cortical Culture.	eNeuro	2021
34222254	Transcriptome Profiling of Mouse Corpus Callosum After Cerebral Hypoperfusion.	Frontiers in Cell and Developmental Biology	2021
33939228	Small-World Networks and Their Relationship With Hippocampal Glutamine/Glutamate Concentration in Healthy Adults With Varying Genetic Risk for Alzheimer's Disease.	J Magn Reson Imaging	2021
34309092	Asymmetric left-right hippocampal glutamatergic modulation of cognitive control in ApoE-isoform subjects is unrelated to neuroinflammation.	Eur J Neurosci	2021
32757690	ATM loss disrupts the autophagy-lysosomal pathway.		2021
31381155	Marine bacterial extracts as a new rich source of drugs against Alzheimer's disease.	Journal of Neurochemistry	2020
31955914	Cyclin-Dependent Kinase 5-Dependent BAG3 Degradation Modulates Synaptic Protein Turnover.	Biological Psychiatry	2020
32062842	Context-Dependent Functions of E2F1: Cell Cycle, Cell Death, and DNA Damage Repair in Cortical Neurons.	Molecular Neurobiology	2020
33828783	Viewing garden scenes: Interaction between Gaze Behavior and Physiological Responses.	Journal of Eye Movement Research	2020
33058355	Selective loss of 5hmC promotes neurodegeneration in the mouse model of Alzheimer's disease.	FASEB Journal	2020
32500736	The Mechanism of Relaxation by Viewing a Japanese Garden: A Pilot Study.	HERD	2020
31189575	Accumulation of Cytoplasmic DNA Due to ATM Deficiency Activates the Microglial Viral Response System with Neurotoxic Consequences.	Journal of Neuroscience	2019
31636448	Age-related hyperinsulinemia leads to insulin resistance in neurons and cell-cycle-induced senescence.	Nature Neuroscience	2019
30642892	ATM is activated by ATP depletion and modulates mitochondrial function through NRF1.	Journal of Cell Biology	2019
30682813	Testing the Neuroprotective Properties of PCSO-524 Using a Neuronal Cell Cycle Suppression Assay.	Marine Drugs	2019
31359030	LATE to the PART-y.	Brain	2019
29279380	ATM and ATR play complementary roles in the behavior of excitatory and inhibitory vesicle populations.	Proceedings of the National Academy of Sciences of the United States of America	2018
30507568	The Positive Effects of Viewing Gardens for Persons with Dementia.	Journal of Alzheimer's Disease	2018
30400801	Ibuprofen prevents progression of ataxia telangiectasia symptoms in ATM-deficient mice.	Journal of Neuroinflammation	2018
30440689	Physiological Responses of the Youth Viewing a Japanese Garden.	Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference	2018
29328926	DNA damage-associated oligodendrocyte degeneration precedes amyloid pathology and contributes to Alzheimer's disease and dementia.	Alzheimer's and Dementia	2018
28081717	Erratum to: The impact of glutamine supplementation on the symptoms of ataxia-telangiectasia: a preclinical assessment.	Molecular Neurodegeneration	2017
28643564	The Power of Traditional Design Techniques: The Effects of Viewing a Japanese Garden on Individuals With Cognitive Impairment.	HERD	2017
28547865	Re-imagining Alzheimer's disease - the diminishing importance of amyloid and a glimpse of what lies ahead.	Journal of Neurochemistry	2017
28849789	Loopholes in the DNA contract kill neurons.	Nature Neuroscience	2017
29060230	Remote gaze tracking system for 3D environments.	Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference	2017
27235538	DNA damage in the oligodendrocyte lineage and its role in brain aging.	Mechanisms of Ageing and Development	2017
28238799	Inhibition of Drp1 hyper-activation is protective in animal models of experimental multiple sclerosis.	Experimental Neurology	2017
27538496	The impact of glutamine supplementation on the symptoms of ataxia-telangiectasia: a preclinical assessment.	Molecular Neurodegeneration	2016
27022623	Neurons in Vulnerable Regions of the Alzheimer's Disease Brain Display Reduced ATM Signaling.	eNeuro	2016
27189786	Multicolor 4D Fluorescence Microscopy using Ultrathin Bessel Light Sheets.	Scientific Reports	2016
26788729	Non-Neuronal Cells Are Required to Mediate the Effects of Neuroinflammation: Results from a Neuron-Enriched Culture System.	PLoS ONE	2016
27075534	ATM protein is located on presynaptic vesicles and its deficit leads to failures in synaptic plasticity.	Journal of Neurophysiology	2016
27875306	Family-wide Structural Characterization and Genomic Comparisons Decode the Diversity-oriented Biosynthesis of Thalassospiramides by Marine Proteobacteria.	Journal of Biological Chemistry	2016
26462757	Genomic integrity and the ageing brain.	Nature Reviews Neuroscience	2015
25792098	Neuroinflammation in Alzheimer's disease.	Lancet Neurol	2015
25673854	The roles of Cdk5-mediated subcellular localization of FOXO1 in neuronal death.	Journal of Neuroscience	2015
26007212	The case for rejecting the amyloid cascade hypothesis.	Nature Neuroscience	2015
26510954	Alteration in 5-hydroxymethylcytosine-mediated epigenetic regulation leads to Purkinje cell vulnerability in ATM deficiency.	Brain	2015