Author details

Full Name

Webster K Cavenee

Affiliation

Ludwig Institute for Cancer Research, University of California San Diego

ORCID

Career Start Year

1977

Papers

333

H Index

106

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36645410	Dysregulation of the PRUNE2/PCA3 genetic axis in human prostate cancer: from experimental discovery to validation in two independent patient cohorts.	Elife	2023
37922327	MDA-9/Syntenin in the tumor and microenvironment defines prostate cancer bone metastasis.	Proc Natl Acad Sci U S A	2023
35271755	The metabolomic landscape plays a critical role in glioma oncogenesis.	Cancer Sci	2022
36395141	Somatic 9p24.1 alterations in HPV<sup>-</sup> head and neck squamous cancer dictate immune microenvironment and anti-PD-1 checkpoint inhibitor activity.	Proc Natl Acad Sci U S A	2022
33952700	Immune evasion in HPV<sup>-</sup> head and neck precancer-cancer transition is driven by an aneuploid switch involving chromosome 9p loss.	Proc Natl Acad Sci U S A	2021
33503971	A Mathematical Model to Estimate Chemotherapy Concentration at the Tumor-Site and Predict Therapy Response in Colorectal Cancer Patients with Liver Metastases.	Cancers (Basel)	2021
33916219	Protein Acetylation at the Interface of Genetics, Epigenetics and Environment in Cancer.	Metabolites	2021
35008495	Insights into the Mechanisms of Action of MDA-7/IL-24: A Ubiquitous Cancer-Suppressing Protein.	Int J Mol Sci	2021
34016751	Pharmacological inhibition of MDA-9/Syntenin blocks breast cancer metastasis through suppression of IL-1Î².	Proc Natl Acad Sci U S A	2021
31130731	Targeted AAVP-based therapy in a mouse model of human glioblastoma: a comparison of cytotoxic versus suicide gene delivery strategies.	Cancer Gene Ther	2020
32061839	MDA-9/Syntenin (SDCBP): Novel gene and therapeutic target for cancer metastasis.	Pharmacol Res	2020
32366675	Dual Regulation of Histone Methylation by mTOR Complexes Controls Glioblastoma Tumor Cell Growth via EZH2 and SAM.	Mol Cancer Res	2020
32472073	Tumour predisposition and cancer syndromes as models to study gene-environment interactions.	Nat Rev Cancer	2020
32145344	mTOR complex 2 is an integrator of cancer metabolism and epigenetics.	Cancer Lett	2020
32409605	Lumefantrine, an antimalarial drug, reverses radiation and temozolomide resistance in glioblastoma.	Proc Natl Acad Sci U S A	2020
30609184	Metabolic reprogramming in the pathogenesis of glioma: Update.	Neuropathology	2019
31712311	mTORC2 links growth factor signaling with epigenetic regulation of iron metabolism in glioblastoma.	J Biol Chem	2019
31821785	Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair.	Cancer Cell	2019
31303424	Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling.	Cell Metab	2019
30842276	MDA-7/IL-24 regulates the miRNA processing enzyme DICER through downregulation of MITF.	Proc Natl Acad Sci U S A	2019
30858324	Detection of early-stage hepatocellular carcinoma in asymptomatic HBsAg-seropositive individuals by liquid biopsy.	Proc Natl Acad Sci U S A	2019
30827889	Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair.	Cancer Cell	2019
31085179	Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair.	Cancer Cell	2019
31028138	Oncogenic mutations at the EGFR ectodomain structurally converge to remove a steric hindrance on a kinase-coupled cryptic epitope.	Proc Natl Acad Sci U S A	2019
30681320	Rethinking Glioblastoma Therapy: MDA-9/Syntenin Targeted Small Molecule.	ACS Chem Neurosci	2019
30476961	Emerging Pharmacologic Targets in Cerebral Cavernous Malformation and Potential Strategies to Alter the Natural History of a Difficult Disease: A Review.	JAMA Neurol	2019
30659021	Blockade of a Laminin-411-Notch Axis with CRISPR/Cas9 or a Nanobioconjugate Inhibits Glioblastoma Growth through Tumor-Microenvironment Cross-talk.	Cancer Res	2019
28814435	Adaptive Global Innovative Learning Environment for Glioblastoma: GBM AGILE.	Clin Cancer Res	2018
30118375	Regulation of protective autophagy in anoikis-resistant glioma stem cells by SDCBP/MDA-9/Syntenin.	Autophagy	2018
30087190	Reply to Yoshida: Delineating critical roles of MDA-9 in protective autophagy-mediated anoikis resistance in human glioma stem cells.	Proc Natl Acad Sci U S A	2018
30323273	Consensus report of the 8 and 9th Weinman Symposia on Gene x Environment Interaction in carcinogenesis: novel opportunities for precision medicine.	Cell Death Differ	2018
29757276	Fluorescence Molecular Tomography for In Vivo Imaging of Glioblastoma Xenografts.	J Vis Exp	2018
29799523	Publisher Correction: PTEN regulates glioblastoma oncogenesis through chromatin-associated complexes of DAXX and histone H3.3.	Nat Commun	2018
29760085	MDA-9/Syntenin regulates protective autophagy in anoikis-resistant glioma stem cells.	Proc Natl Acad Sci U S A	2018
29321665	FHL2 interacts with EGFR to promote glioblastoma growth.	Oncogene	2018
28011764	Inhibition of radiation-induced glioblastoma invasion by genetic and pharmacological targeting of MDA-9/Syntenin.	Proc Natl Acad Sci U S A	2017
29872691	Precision cancer therapy is impacted by oncogene-dependent epigenome remodeling.	NPJ Precis Oncol	2017
28497778	PTEN regulates glioblastoma oncogenesis through chromatin-associated complexes of DAXX and histone H3.3.	Nat Commun	2017
28178237	Extrachromosomal oncogene amplification drives tumour evolution and genetic heterogeneity.	Nature	2017
29203859	Interleukin-13 receptor alpha 2 cooperates with EGFRvIII signaling to promote glioblastoma multiforme.	Nat Commun	2017
28751581	Going viral? Linking the etiology of human prostate cancer to the <i>PCA3</i> long noncoding RNA and oncogenic viruses.	EMBO Mol Med	2017
28724615	Glioblastoma cellular cross-talk converges on NF-ÎºB to attenuate EGFR inhibitor sensitivity.	Genes Dev	2017
28607091	Selective replication of oncolytic virus M1 results in a bystander killing effect that is potentiated by Smac mimetics.	Proc Natl Acad Sci U S A	2017
25893308	IGFBP2 potentiates nuclear EGFR-STAT3 signaling.	Oncogene	2016
27746144	An LXR-Cholesterol Axis Creates a Metabolic Co-Dependency for Brain Cancers.	Cancer Cell	2016
27825958	Simultaneous blockade of interacting CK2 and EGFR pathways by tumor-targeting nanobioconjugates increases therapeutic efficacy against glioblastoma multiforme.	J Control Release	2016
27427440	mTORC2 activity in brain cancer: Extracellular nutrients are required to maintain oncogenic signaling.	Bioessays	2016
27295313	Cancer metabolism as a central driving force of glioma pathogenesis.	Brain Tumor Pathol	2016
27157931	The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary.	Acta Neuropathol	2016
27070703	Single-Cell Phosphoproteomics Resolves Adaptive Signaling Dynamics and Informs Targeted Combination Therapy in Glioblastoma.	Cancer Cell	2016

1 - 50 of 333

Massimo Squatrito

Seve Ballesteros Foundation Brain Tumor group

Career Start Year 2002

Number of shared co-authors 4

Jan Koster

Amsterdam University Medical Centers location AMC

Career Start Year 1999

Number of shared co-authors 18

Robert L Walker

Center for Cancer Research, National Cancer Institute, National Institutes of Health

Career Start Year 1997

Number of shared co-authors 3

Agnes Viale

Memorial Sloan Kettering Cancer Center

Career Start Year 1996

Number of shared co-authors 2

Marbin Pineda

Center for Cancer Research, National Cancer Institute

Career Start Year 1995

Number of shared co-authors 1

Zhengping Zhuang

National Cancer Institute, National Institutes of Health

Career Start Year 1994

Number of shared co-authors 3

Kristina A Cole

Perelman School of Medicine, University of Pennsylvania

Career Start Year 1994

Number of shared co-authors 8

Marietta Wolter

Institute of Neuropathology, Heinrich Heine University

Career Start Year 1993

Number of shared co-authors 10

Sanja Pajovic

Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children

Career Start Year 1993

Number of shared co-authors 5

John Easton

St Jude Children's Research Hospital

Career Start Year 1991

Number of shared co-authors 9

Glenn S Cowley

Broad Institute of Harvard and MIT

Career Start Year 1990

Number of shared co-authors 4

Antonio Iavarone

Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami

Career Start Year 1989

Number of shared co-authors 24

E Alejandro Sweet-Cordero

University of California San Francisco

Career Start Year 1989

Number of shared co-authors 4

Todd R Golub

Broad Institute of MIT and Harvard

Career Start Year 1989

Number of shared co-authors 20

Olivier Delattre

PSL Research University, Institut Curie Research Center, INSERM U, Institut Curie

Career Start Year 1987

Number of shared co-authors 15

Peter Lichter

German Cancer Research Center (DKFZ)

Career Start Year 1986

Number of shared co-authors 21

Ann M Killary

The University of Texas M. D. Anderson Cancer Center

Career Start Year 1984

Number of shared co-authors 4

Olli Kallioniemi

Karolinska Institute

Career Start Year 1984

Number of shared co-authors 6

Gaetano Finocchiaro

IRCCS San Raffaele Scientific Institute

Career Start Year 1983

Number of shared co-authors 28

Ola Myklebost

Institute for Cancer Research, Oslo University Hospital

Career Start Year 1983

Number of shared co-authors 4

Matthew Meyerson

Broad Institute

Career Start Year 1983

Number of shared co-authors 38

Ching C Lau

Baylor College of Medicine

Career Start Year 1982

Number of shared co-authors 12

Alan Ashworth

UCSF Helen Diller Family Comprehensive Cancer Center

Career Start Year 1982

Number of shared co-authors 12

Edison T Liu

USA The Jackson Laboratory Cancer Center

Career Start Year 1982

Number of shared co-authors 6

David J Adams

Wellcome Sanger Institute

Career Start Year 1980

Number of shared co-authors 8

David M Thomas

Garvan Institute of Medical Research

Career Start Year 1980

Number of shared co-authors 3

Francisca Vazquez

Broad Institute of MIT and Harvard

Career Start Year 1979

Number of shared co-authors 6

Colin S Cooper

Norwich Medical School, University of East Anglia

Career Start Year 1978

Number of shared co-authors 11

Raju Kucherlapati

Harvard Medical School

Career Start Year 1973

Number of shared co-authors 21

Paul S Meltzer

Center for Cancer Research, National Cancer Institute, National Institutes of Health

Career Start Year 1970

Number of shared co-authors 14

row(s) 1 - 30 of 30

Frank B Furnari

University of California San Diego

Co-authored papers 86

H-J Su Huang

Regeneron Pharmaceuticals Inc.

Co-authored papers 49

Paul S Mischel

Stanford University

Co-authored papers 40

Motoo Nagane

Kyorin University Faculty of Medicine

Co-authored papers 22

Timothy F Cloughesy

David Geffen School of Medicine, University of California Los Angeles

Co-authored papers 22

Charles D James

Co-authored papers 18

Wadih Arap

Rutgers Cancer Institute of New Jersey

Co-authored papers 14

Irene F Newsham

MD Anderson Cancer Center

Co-authored papers 12

Ryo Nishikawa

Saitama Medical University International Medical Center

Co-authored papers 12

Oliver B??gler

American Association for Cancer Research, Henry Ford Hospital, Ludwig Institute for Cancer Research, National Cancer Institute, Salk Institute for Biological Studies, University of Cambridge, University of Texas MD Anderson Cancer Center, Virginia Commonwealth University

Co-authored papers 11

Shi-Yuan Cheng

Northwestern University Feinberg School of Medicine

Co-authored papers 11

Terrance G Johns

Telethon Kids Institute

Co-authored papers 10

Joseph F Costello

University of California san francisco

Co-authored papers 8

Clark C Chen

University of Minnesota