Author details

Full Name

Claes Wahlestedt

Affiliation

ORCID

Career Start Year

1982

Papers

308

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37509143	Dopamine Transporter Knockout Rats Display Epigenetic Alterations in Response to Cocaine Exposure.		2023
37759724	Low-Dose Chidamide Treatment Displays Sex-Specific Differences in the 3xTg-AD Mouse.		2023
37662844	Nucleic acid-based therapeutics for the treatment of central nervous system disorders.		2023
37288167	Transcriptomics for Clinical and Experimental Biology Research: Hang on a Seq.	Adv Genet (Hoboken)	2023
37466388	Long non-coding RNA-targeting therapeutics: discovery and development update.		2023
36765087	Author Correction: Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis.	Nat Commun	2023
37253858	Amplifying gene expression with RNA-targeted therapeutics.		2023
37171575	Investigating the Synergistic Potential of Low-Dose HDAC3 Inhibition and Radiotherapy in Alzheimer's Disease Models.		2023
34757001	JQ1 attenuates psychostimulant- but not opioid-induced conditioned place preference.	Behavioural Brain Research	2022
36250017	Natural antisense transcripts as drug targets.	Frontiers in Molecular Biosciences	2022
36077629	Functional Drug Screening of Small Molecule Inhibitors of Epigenetic Modifiers in Refractory AML Patients.	Cancers (Basel)	2022
35789594	Safety and pharmacokinetics of a highly bioavailable resveratrol preparation (JOTROL ).		2022
35723129	Erratum to: JOTROL, a Novel Formulation of Resveratrol, Shows Beneficial Effects in the 3xTg-AD Mouse Model.	Journal of Alzheimer's Disease	2022
34735897	A novel strategy for combination of clofarabine and pictilisib is synergistic in gastric cancer.	Transl Oncol	2022
35037854	A human-based multi-gene signature enables quantitative drug repurposing for metabolic disease.	Elife	2022
35135840	DOT1L Is a Novel Cancer Stem Cell Target for Triple-Negative Breast Cancer.	Clinical Cancer Research	2022
31373129	Dysregulation of the histone demethylase KDM6B in alcohol dependence is associated with epigenetic regulation of inflammatory signaling pathways.	Addict Biol	2021
33996898	Nucleic Acid-Based Therapeutics in Orphan Neurological Disorders: Recent Developments.	Frontiers in Molecular Biosciences	2021
33459720	Sexual Dimorphism in the 3xTg-AD Mouse Model and Its Impact on Pre-Clinical Research.	Journal of Alzheimer's Disease	2021
32656646	Direct Administration and Gene Modulation Using Antisense Oligonucleotides Within the CNS.	Cellular and Molecular Neurobiology	2021
33077485	Dual Screen for Efficacy and Toxicity Identifies HDAC Inhibitor with Distinctive Activity Spectrum for BAP1-Mutant Uveal Melanoma.	Molecular Cancer Research	2021
33414398	Alcohol use disorder causes global changes in splicing in the human brain.	Transl Psychiatry	2021
34827542	Epigenetic Small Molecules Rescue Nucleocytoplasmic Transport and DNA Damage Phenotypes in C9ORF72 ALS/FTD.	Brain Sciences	2021
34377851	A novel knockout mouse model of the noncoding antisense () gene displays increased endogenous Bdnf protein and improved memory function following exercise.	Heliyon	2021
32831302	A Neurite Outgrowth Assay and Neurotoxicity Assessment with Human Neural Progenitor Cell-Derived Neurons.	Journal of Visualized Experiments	2020
32093728	Dipeptide repeat proteins inhibit homology-directed DNA double strand break repair in C9ORF72 ALS/FTD.	Molecular Neurodegeneration	2020
33584810	Emerging Technologies for Genome-Wide Profiling of DNA Breakage.	Frontiers in Genetics	2020
32882003	Antitumor activity of the dual BET and CBP/EP300 inhibitor NEO2734.	Blood advances	2020
32755574	Molecular Transducers of Human Skeletal Muscle Remodeling under Different Loading States.	Cell Reports	2020
33080337	Molecular mechanisms of psychiatric diseases.	Neurobiology of Disease	2020
32913560	The bromodomain inhibitor IBET-151 attenuates vismodegib-resistant esophageal adenocarcinoma growth through reduction of GLI signaling.	Oncotarget	2020
31311938	Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis.	Nat Commun	2019
31559706	The novel BET-CBP/p300 dual inhibitor NEO2734 is active in SPOP mutant and wild-type prostate cancer.	EMBO Mol Med	2019
31862872	Novel approach reveals genomic landscapes of single-strand DNA breaks with nucleotide resolution in human cells.	Nature Communications	2019
30504275	Enhancement of BDNF Expression and Memory by HDAC Inhibition Requires BET Bromodomain Reader Proteins.	J Neurosci	2019
30975544	Vitamin C supplementation expands the therapeutic window of BETi for triple negative breast cancer.	EBioMedicine	2019
31168962	Longevity-related molecular pathways are subject to midlife "switch" in humans.	Aging Cell	2019
31366484	Ovarian Cancer Treatment Stratification Using Drug Sensitivity Testing.	Anticancer Research	2019
30841499	HDAC Inhibitors Induce Expression and Promote Neurite Outgrowth in Human Neural Progenitor Cells-Derived Neurons.	International Journal of Molecular Sciences	2019
28040748	How the strengths of Lisp-family languages facilitate building complex and flexible bioinformatics applications.	Brief Bioinform	2018
30552330	Drug and disease signature integration identifies synergistic combinations in glioblastoma.	Nat Commun	2018
30397132	Inhibition of HDAC3 reverses Alzheimer's disease-related pathologies in vitro and in the 3xTg-AD mouse model.	Proceedings of the National Academy of Sciences of the United States of America	2018
30212533	Ex vivo drug sensitivity testing as a means for drug repurposing in esophageal adenocarcinoma.	PLoS ONE	2018
30017313	Strategies to Annotate and Characterize Long Noncoding RNAs: Advantages and Pitfalls.	Trends in Genetics	2018
30099093	EZH1 is an antipsychotic-sensitive epigenetic modulator of social and motivational behavior that is dysregulated in schizophrenia.	Neurobiol Dis	2018
30582583	Purification of H3 and H4 Histone Proteins and the Quantification of Acetylated Histone Marks in Cells and Brain Tissue.	Journal of Visualized Experiments	2018
30078338	Developments in lncRNA drug discovery: where are we heading?	Expert Opinion on Drug Discovery	2018
29986096	A coding and non-coding transcriptomic perspective on the genomics of human metabolic disease.	Nucleic Acids Res	2018
29180474	Vitamin C Sensitizes Melanoma to BET Inhibitors.	Cancer Res	2018
29483230	Cocaine Exposure Increases Blood Pressure and Aortic Stiffness via the miR-30c-5p-Malic Enzyme 1-Reactive Oxygen Species Pathway.	Hypertension	2018