Skip to Main Content

Author Details

Ralf Kittler
McDermott Center for Human Growth and Development.
1984
67
34
PMIDPaper TitleJournal TitlePublished Year
36330954Ablation of EWS-FLI1 by USP9X inhibition suppresses cancer cell growth in Ewing sarcoma.Cancer Lett2023
37035141Glucocorticoid mediated inhibition of LKB1 mutant non-small cell lung cancers.Front Oncol2023
36780194ALK Amplification and Rearrangements Are Recurrent Targetable Events in Congenital and Adult Glioblastoma.Clin Cancer Res2023
36454649Global chromatin landscapes identify candidate noncoding modifiers of cardiac rhythm.J Clin Invest2023
34782721Correction to: Hormonal modulation of ESR1 mutant metastasis.Oncogene2022
33096336Dynamic differences between DNA damage repair responses in primary tumors and cell lines.Transl Oncol2021
34580063Elimination of Radiation-Induced Senescence in the Brain Tumor Microenvironment Attenuates Glioblastoma Recurrence.Cancer Res2021
34752753Structure-based classification of EGFR mutations informs inhibitor selection for lung cancer therapy.Cancer Cell2021
34301758Lentiviral-Driven Discovery of Cancer Drug Resistance Mutations.Cancer Res2021
34011560Nuclear FGFR1 Regulates Gene Transcription and Promotes Antiestrogen Resistance in ER<sup>+</sup> Breast Cancer.Clin Cancer Res2021
32485222Mithramycin suppresses DNA damage repair via targeting androgen receptor in prostate cancer.Cancer Lett2020
31839537GCNA Preserves Genome Integrity and Fertility Across Species.Dev Cell2020
31883965RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer.Cell Chem Biol2020
32512502An in vivo functional genomics screen of nuclear receptors and their co-regulators identifies FOXA1 as an essential gene in lung tumorigenesis.Neoplasia2020
31088835Radiation-Induced DNA Damage Cooperates with Heterozygosity of TP53 and PTEN to Generate High-Grade Gliomas.Cancer Res2019
29258679Role of Androgen Receptor Variants in Prostate Cancer: Report from the 2017 Mission Androgen Receptor Variants Meeting.Eur Urol2018
30217566Targeting the turnover of oncoproteins as a new avenue for therapeutics development in castration-resistant prostate cancer.Cancer Lett2018
30420515PPARγ-K107 SUMOylation regulates insulin sensitivity but not adiposity in mice.Proc Natl Acad Sci U S A2018
29749794Molecular Cytogenetics Guides Massively Parallel Sequencing of a Radiation-Induced Chromosome Translocation in Human Cells.Radiat Res2018
29507699Grade progression in urothelial carcinoma can occur with high or low mutational homology: a first-step toward tumor-specific care in initial low-grade bladder cancer.Oncotarget2018
29108672FoxA transcription factor Fork head maintains the intestinal stem/progenitor cell identities in Drosophila.Dev Biol2018
28538184Taxane-Platin-Resistant Lung Cancers Co-develop Hypersensitivity to JumonjiC Demethylase Inhibitors.Cell Rep2017
28455392Biomarker Accessible and Chemically Addressable Mechanistic Subtypes of BRAF Melanoma.Cancer Discov2017
28122245Oncogenes Activate an Autonomous Transcriptional Regulatory Circuit That Drives Glioblastoma.Cell Rep2017
28263985Robust stratification of breast cancer subtypes using differential patterns of transcript isoform expression.PLoS Genet2017
29264534Identification of the Underlying Androgen Receptor Defect in the Dallas Reifenstein Family.J Endocr Soc2017
27425409HP1BP3, a Chromatin Retention Factor for Co-transcriptional MicroRNA Processing.Mol Cell2016
28881577A comprehensively characterized cell line panel highly representative of clinical ovarian high-grade serous carcinomas.Oncotarget2016
27626314The ubiquitin ligase TRIM25 targets ERG for degradation in prostate cancer.Oncotarget2016
25043300DAB2IP regulates cancer stem cell phenotypes through modulating stem cell factor receptor and ZEB1.Oncogene2015
26484581Minireview: Familiar Faces in Unfamiliar Places: The Emerging Role of Nuclear Receptors in Lung Cancer.Mol Endocrinol2015
26456834Unsaturated Fatty Acids Stimulate Tumor Growth through Stabilization of β-Catenin.Cell Rep2015
27308443Harnessing the nuclear receptor PPARγ to inhibit the growth of lung adenocarcinoma by rewiring metabolic circuitries.Mol Cell Oncol2015
25722209TCF4 Triplet Repeat Expansion and Nuclear RNA Foci in Fuchs' Endothelial Corneal Dystrophy.Invest Ophthalmol Vis Sci2015
24625679Lsd1 restricts the number of germline stem cells by regulating multiple targets in escort cells.PLoS Genet2014
26484153An integrated functional genomic analysis identifies the antitumorigenic mechanism of action for PPARγ in lung cancer cells.Genom Data2014
25264247Inhibition of cancer cell proliferation by PPARγ is mediated by a metabolic switch that increases reactive oxygen species levels.Cell Metab2014
24591637Ablation of the oncogenic transcription factor ERG by deubiquitinase inhibition in prostate cancer.Proc Natl Acad Sci U S A2014
23375374A comprehensive nuclear receptor network for breast cancer cells.Cell Rep2013
23685356HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitment.EMBO J2013
23213231Neuregulin 1-HER axis as a key mediator of hyperglycemic memory effects in breast cancer.Proc Natl Acad Sci U S A2012
22102826Consequences of eukaryotic enhancer architecture for gene expression dynamics, development, and fitness.PLoS Genet2011
21060808Allele-specific down-regulation of RPTOR expression induced by retinoids contributes to climate adaptations.PLoS Genet2010
19563758Genomic antagonism between retinoic acid and estrogen signaling in breast cancer.Cell2009
19345177A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity.Cell Stem Cell2009
19427217HAUS, the 8-subunit human Augmin complex, regulates centrosome and spindle integrity.Curr Biol2009
19387489Comparative profiling identifies C13orf3 as a component of the Ska complex required for mammalian cell division.EMBO J2009
18391959BAC TransgeneOmics: a high-throughput method for exploration of protein function in mammals.Nat Methods2008
18635956Systems biology of mammalian cell division.Cell Cycle2008
18207742The mammalian SPD-2 ortholog Cep192 regulates centrosome biogenesis.Curr Biol2008
  • 1 - 50 of 67

Recommended Authors

The University of Texas Southwestern Medical Center
Career Start Year 2016
Number of shared co-authors 5
Weill Cornell Medical College.
Career Start Year 2013
Number of shared co-authors 3
College of Medicine, University of Saskatchewan
Career Start Year 2010
Number of shared co-authors 1
Center for Cell Signaling, University of Virginia
Career Start Year 2010
Number of shared co-authors 0
The Francis Crick Institute
Career Start Year 2008
Number of shared co-authors 3
The National Institutes of Health
Career Start Year 2006
Number of shared co-authors 2
The University of Texas MD Anderson Cancer Center
Career Start Year 2006
Number of shared co-authors 0
Cancer Science Institute of Singapore, National University of Singapore
Career Start Year 2005
Number of shared co-authors 0
CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
Career Start Year 2003
Number of shared co-authors 1
The Wistar Institute
Career Start Year 2003
Number of shared co-authors 1
Roswell Park Comprehensive Cancer Center
Career Start Year 2003
Number of shared co-authors 1
Fox Chase Cancer Center
Career Start Year 2002
Number of shared co-authors 0
Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai
Career Start Year 2001
Number of shared co-authors 1
College Street, University of Toronto
Career Start Year 2000
Number of shared co-authors 1
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Career Start Year 1997
Number of shared co-authors 0
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Career Start Year 1997
Number of shared co-authors 0
University of Toronto
Career Start Year 1997
Number of shared co-authors 3
The Ohio State University
Career Start Year 1997
Number of shared co-authors 1
University of Alabama at Birmingham
Career Start Year 1997
Number of shared co-authors 0
University of British Columbia
Career Start Year 1993
Number of shared co-authors 5
Broad Institute of Harvard and MIT
Career Start Year 1993
Number of shared co-authors 12
Broad Institute of Harvard and MIT
Career Start Year 1990
Number of shared co-authors 4
The University of Melbourne
Career Start Year 1990
Number of shared co-authors 2
Broad Institute of MIT and Harvard
Career Start Year 1989
Number of shared co-authors 12
Broad Institute of MIT and Harvard, USA Dana-Farber Cancer Institute
Career Start Year 1987
Number of shared co-authors 13
Center for Bioinformatics, University of Oslo
Career Start Year 1987
Number of shared co-authors 2
Howard Hughes Medical Institute, Brigham and Women's Hospital, Harvard Medical School
Career Start Year 1982
Number of shared co-authors 3
UCSF Helen Diller Family Comprehensive Cancer Center
Career Start Year 1982
Number of shared co-authors 9
Wellcome Sanger Institute
Career Start Year 1980
Number of shared co-authors 6
Broad Institute of MIT and Harvard
Career Start Year 1979
Number of shared co-authors 4

Collaborators

McDermott Center for Human Growth and Development.
Co-authored papers 25
University Hospital Carl Gustav Carus, Technische Universitat (TU) Dresden
Co-authored papers 16
McDermott Center for Human Growth and Development, UT Southwestern Medical Center
Co-authored papers 8
University of Texas Southwestern Medical Center at Dallas
Co-authored papers 7
Max Planck Institute of Molecular Cell Biology and Genetics
Co-authored papers 7
University of Texas Southwestern Medical Center at Dallas
Co-authored papers 6
Max Planck Institute of Molecular Cell Biology and Genetics
Co-authored papers 6
Co-authored papers 5
Medical Faculty and University Hospital Carl Gustav Carus
Co-authored papers 5
Aix Marseille University, CNRS, Turing Center for Living Systems
Co-authored papers 5
Co-authored papers 5
Co-authored papers 3
Hamon Center for Therapeutic Oncology Research, UT Southwestern Medical Center
Co-authored papers 3
University of Texas Southwestern Medical Center
Co-authored papers 3
University of Texas Southwestern Medical Center
Co-authored papers 3
The University of Texas Southwestern Medical Center
Co-authored papers 2
Center for Molecular and Cellular Bioengineering, Technische Universitat Dresden
Co-authored papers 2
Max Planck Institute of Molecular Cell Biology and Genetics
Co-authored papers 2
Quantitative Biomedical Research Center
Co-authored papers 2
University of Georgia
Co-authored papers 2
Faculty of Medicine and University Hospital Carl Gustav Carus
Co-authored papers 2
University of Texas Southwestern Medical Center
Co-authored papers 2
University of Washington
Co-authored papers 2
University of British Columbia
Co-authored papers 2
University of Cambridge
Co-authored papers 1
Rogel Cancer Center, University of Michigan Medical School ann arbor
Co-authored papers 1
University of Texas Southwestern Medical Center
Co-authored papers 1
Wellcome Sanger Institute
Co-authored papers 1
University of Chicago
Co-authored papers 1
Co-authored papers 1