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Author Details

Bo Lundgren
Stockholm University
1987
40
20
Emma Lundberg (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
35142215Ultralarge Virtual Screening Identifies SARS-CoV-2 Main Protease Inhibitors with Broad-Spectrum Activity against Coronaviruses.J Am Chem Soc2022
32199331Comprehensive chemical proteomics for target deconvolution of the redox active drug auranofin.Redox Biol2020
32605631High content drug screening for Fanconi anemia therapeutics.Orphanet J Rare Dis2020
32668248A Patient-Derived Cell Atlas Informs Precision Targeting of Glioblastoma.Cell Rep2020
29428596Small molecule PGC-1α1 protein stabilizers induce adipocyte Ucp1 expression and uncoupled mitochondrial respiration.Mol Metab2018
28655422Diverse heterocyclic scaffolds as dCTP pyrophosphatase 1 inhibitors. Part 2: Pyridone- and pyrimidinone-derived systems.Bioorg Med Chem Lett2017
28447629Corrigendum: MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool.Nature2017
28145708Identification of Triazolothiadiazoles as Potent Inhibitors of the dCTP Pyrophosphatase 1.J Med Chem2017
29142246A comprehensive structural, biochemical and biological profiling of the human NUDIX hydrolase family.Nat Commun2017
28687206Diverse heterocyclic scaffolds as dCTP pyrophosphatase 1 inhibitors. Part 1: Triazoles, triazolopyrimidines, triazinoindoles, quinoline hydrazones and arylpiperazines.Bioorg Med Chem Lett2017
27689322Case-specific potentiation of glioblastoma drugs by pterostilbene.Oncotarget2016
24695224MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool.Nature2014
23868472Retinoic acid receptor alpha is associated with tamoxifen resistance in breast cancer.Nat Commun2013
24101737Comparative drug pair screening across multiple glioblastoma cell lines reveals novel drug-drug interactions.Neuro Oncol2013
14747616Oxidation of protein tyrosine phosphatases as a pharmaceutical mechanism of action: a study using 4-hydroxy-3,3-dimethyl-2H-benzo[g]indole-2,5(3H)-dione.J Pharmacol Exp Ther2004
15585823A proteomics approach to the study of absorption, distribution, metabolism, excretion, and toxicity.J Biomol Tech2004
15465028Stable suppression of MDR1 gene expression and function by RNAi in Caco-2 cells.Biochem Biophys Res Commun2004
15380819The expression of cytosolic and mitochondrial type II acyl-CoA thioesterases is upregulated in the porcine corpus luteum during pregnancy.Prostaglandins Leukot Essent Fatty Acids2004
11561076Correlation of gene expression of ten drug efflux proteins of the ATP-binding cassette transporter family in normal human jejunum and in human intestinal epithelial Caco-2 cell monolayers.J Pharmacol Exp Ther2001
11230808Changes in the generation of reactive oxygen species and in mitochondrial membrane potential during apoptosis induced by the antidepressants imipramine, clomipramine, and citalopram and the effects on these changes by Bcl-2 and Bcl-X(L).Biochem Pharmacol1999
9576850Characterization of the UDP-glucuronosyltransferase isoenzyme expressed in rat ovary and its regulation by gonadotropins.Biochem J1998
9620880Growth hormone- and testosterone-dependent regulation of glutathione transferase subunit A5 in rat liver.Biochem J1998
8018466Comparison of the potencies of (+)- and (-)-2-ethylhexanoic acid in causing peroxisome proliferation and related biological effects in mouse liver.Chirality1994
8237058Effects of perfluoro fatty acids on peroxisome proliferation and mitochondrial size in mouse liver: dose and time factors and effect of chain length.Xenobiotica1993
8320056Effects of selenium deficiency on xenobiotic-metabolizing and other enzymes in rat liver.Int J Vitam Nutr Res1993
1293309Perfluorooctanoic acid has persistent effects on peroxisome proliferation and related parameters in mouse liver.J Biochem Toxicol1992
1458550The involvement of selenium in peroxisome proliferation caused by dietary administration of clofibrate to rats.Chem Biol Interact1992
1417940Effects of perfluoro fatty acids on xenobiotic-metabolizing enzymes, enzymes which detoxify reactive forms of oxygen and lipid peroxidation in mouse liver.Biochem Pharmacol1992
1499733Is the cytosolic catalase induced by peroxisome proliferators in mouse liver on its way to the peroxisomes?FEBS Lett1992
1599794Interaction of phospholipids with rhodamine 6G in toluene.Acta Chem Scand (Cph)1992
1540233Effects of dietary treatment with 11 dicarboxylic acids, diethylcarboxylic esters and fatty acids on peroxisomal fatty acid beta-oxidation, epoxide hydrolases and lauric acid omega-hydroxylation in mouse liver.Biochem Pharmacol1992
2040306Studies on the intracellular distributions of soluble epoxide hydrolase and of catalase by digitonin-permeabilization of hepatocytes isolated from control and clofibrate-treated mice.Eur J Biochem1991
2267943The metabolism of xenobiotics and its relationship to toxicity/genotoxicity: studies with human lymphocytes.Acta Physiol Scand Suppl1990
2393663Effects of dietary treatment with clofibrate, nafenopin or WY-14.643 on mitochondria and DNA in mouse liver.Biochim Biophys Acta1990
2815829Proliferation of peroxisomes and induction of cytosolic and microsomal epoxide hydrolases in different strains of mice and rats after dietary treatment with clofibrate.Xenobiotica1989
3214886Induction of cytosolic and microsomal epoxide hydrolases in mouse liver by peroxisome proliferators, with special emphasis on structural analogues of 2-ethylhexanoic acid.Chem Biol Interact1988
3111107Induction of xenobiotic-metabolizing enzymes and peroxisome proliferation in rat liver caused by dietary exposure to di(2-ethylhexyl)phosphate.Xenobiotica1987
3028804Examination of the structural requirements for proliferation of peroxisomes and mitochondria in mouse liver by hypolipidemic agents, with special emphasis on structural analogues of 2-ethylhexanoic acid.Eur J Biochem1987
3032197Induction of cytosolic and microsomal epoxide hydrolases and proliferation of peroxisomes and mitochondria in mouse liver after dietary exposure to p-chlorophenoxyacetic acid, 2,4-dichlorophenoxyacetic acid and 2,4,5-trichlorophenoxyacetic acid.Biochem Pharmacol1987
2881746Characterization of the induction of cytosolic and microsomal epoxide hydrolases by 2-ethylhexanoic acid in mouse liver.Drug Metab Dispos1987
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Collaborators

Stockholm University
Co-authored papers 11
Karolinska Institute
Co-authored papers 10
Karolinska Institutet
Co-authored papers 6
Karolinska Institutet
Co-authored papers 6
The University of Sheffield
Co-authored papers 6
Department of Pharmaceutical Biosciences, Uppsala University
Co-authored papers 4
Department of Pharmacy, Uppsala University
Co-authored papers 4
Umea University
Co-authored papers 3
Stockholm University
Co-authored papers 3
Uppsala University
Co-authored papers 2
Karolinska Institutet
Co-authored papers 2
Faculty of Pharmacy, University of Seville
Co-authored papers 2
Karolinska Institutet
Co-authored papers 1
Co-authored papers 1
KTH Royal Institute of Technology
Co-authored papers 1
University of Toronto
Co-authored papers 1
Uppsala University
Co-authored papers 1
Karolinska Institutet
Co-authored papers 1
The Scripps Research Institute
Co-authored papers 1
Sahlgrenska University Hospital
Co-authored papers 1
Co-authored papers 1
Institute for Systems Genetics, NYU Grossman School of Medicine
Co-authored papers 1
Uppsala University
Co-authored papers 1
University of Ljubljana
Co-authored papers 1
Harvard Medical School
Co-authored papers 1
Karolinska Institutet
Co-authored papers 1
Stockholm University
Co-authored papers 1
Karolinska Institutet
Co-authored papers 1
Uppsala University
Co-authored papers 1
Division of Clinical Genetics, Lund University
Co-authored papers 1