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Author Details

Grover C Bagby
Knight Cancer Institute, Oregon Health and Science University
1966
145
54
PMIDPaper TitleJournal TitlePublished Year
36450981Genomic signature of Fanconi anaemia DNA repair pathway deficiency in cancer.Nature2022
33961341Graft-versus-host disease after liver transplantation is associated with bone marrow failure, hemophagocytosis, and DNMT3A mutations.Am J Transplant2021
29399332Recent advances in understanding hematopoiesis in Fanconi Anemia.F1000Res2018
28635072PlGF enhances TLR-dependent inflammatory responses in human mononuclear phagocytes.Am J Reprod Immunol2017
28355571Identification of Interleukin-1 by Functional Screening as a Key Mediator of Cellular Expansion and Disease Progression in Acute Myeloid Leukemia.Cell Rep2017
27053300TGF-β Inhibition Rescues Hematopoietic Stem Cell Defects and Bone Marrow Failure in Fanconi Anemia.Cell Stem Cell2016
26573090Mutant calreticulin-expressing cells induce monocyte hyperreactivity through a paracrine mechanism.Am J Hematol2016
26432900Cytokine overproduction and crosslinker hypersensitivity are unlinked in Fanconi anemia macrophages.J Leukoc Biol2016
27428405Multifunctional Fanconi proteins, inflammation and the Fanconi phenotype.EBioMedicine2016
25534205p38 Mitogen-activated protein kinase inhibition enhances in vitro erythropoiesis of Fanconi anemia, complementation group A-deficient bone marrow cells.Exp Hematol2015
25434823Oxymetholone therapy of fanconi anemia suppresses osteopontin transcription and induces hematopoietic stem cell cycling.Stem Cell Reports2015
23783032The PI3K/Akt1 pathway enhances steady-state levels of FANCL.Mol Biol Cell2013
24046015FANCA and FANCC modulate TLR and p38 MAPK-dependent expression of IL-1β in macrophages.Blood2013
22234699p38 MAPK inhibition suppresses the TLR-hypersensitive phenotype in FANCC- and FANCA-deficient mononuclear phagocytes.Blood2012
23417416The fate of granulosa cells following premature oocyte loss and the development of ovarian cancers.Int J Dev Biol2012
22534332Immune response gene profiles in the term placenta depend upon maternal muscle mass.Reprod Sci2012
22653977FANCL ubiquitinates β-catenin and enhances its nuclear function.Blood2012
21196392The stem cell fitness landscape and pathways of molecular leukemogenesis.Front Biosci (Schol Ed)2011
21860020TNFα facilitates clonal expansion of JAK2V617F positive cells in myeloproliferative neoplasms.Blood2011
20606166Genetic disruption of both Fancc and Fancg in mice recapitulates the hematopoietic manifestations of Fanconi anemia.Blood2010
20826722Fancd2-/- mice have hematopoietic defects that can be partially corrected by resveratrol.Blood2010
20554974Human FANCC is hypomorphic in murine Fancc-deficient cells.Blood2010
19327576Bone marrow failure syndromes. Preface.Hematol Oncol Clin North Am2009
19956396Expression profiling of the ovarian surface kinome reveals candidate genes for early neoplastic changes.Transl Oncol2009
19850743TLR8-dependent TNF-(alpha) overexpression in Fanconi anemia group C cells.Blood2009
19423743Introducing "e-Blood".Blood2009
19327589Myelodysplasia and acute leukemia as late complications of marrow failure: future prospects for leukemia prevention.Hematol Oncol Clin North Am2009
18292805Discovering early molecular determinants of leukemogenesis.J Clin Invest2008
19055840Global rank-invariant set normalization (GRSN) to reduce systematic distortions in microarray data.BMC Bioinformatics2008
18475298Cigarette smoke induces genetic instability in airway epithelial cells by suppressing FANCD2 expression.Br J Cancer2008
18574026TAT-mediated intracellular delivery of NPM-derived peptide induces apoptosis in leukemic cells and suppresses leukemogenesis in mice.Blood2008
18024607Bone marrow failure as a risk factor for clonal evolution: prospects for leukemia prevention.Hematology Am Soc Hematol Educ Program2007
17960249TNF-alpha induces leukemic clonal evolution ex vivo in Fanconi anemia group C murine stem cells.J Clin Invest2007
16608843Nucleophosmin regulates cell cycle progression and stress response in hematopoietic stem/progenitor cells.J Biol Chem2006
16828746Evaluation and lead optimization of anti-malarial acridones.Exp Parasitol2006
16822457Fanconi anemia.Semin Hematol2006
16822456Constitutional marrow failure: Introduction.Semin Hematol2006
16982743Cytogenetic instability in ovarian epithelial cells from women at risk of ovarian cancer.Cancer Res2006
16472069Immune defects in Fanconi anemia.Crit Rev Immunol2006
16397136Natural gene therapy in monozygotic twins with Fanconi anemia.Blood2006
16429406Novel inactivating mutations of FANCC in Brazilian patients with Fanconi anemia.Hum Mutat2006
15735012Generation and molecular characterization of head and neck squamous cell lines of fanconi anemia patients.Cancer Res2005
15356134Impaired type I IFN-induced Jak/STAT signaling in FA-C cells and abnormal CD4+ Th cell subsets in Fancc-/- mice.J Immunol2004
15561690Marrow failure.Hematology Am Soc Hematol Educ Program2004
15299030The Fanconi anemia proteins functionally interact with the protein kinase regulated by RNA (PKR).J Biol Chem2004
15310764Hypoxia-induced nucleophosmin protects cell death through inhibition of p53.J Biol Chem2004
12483114Genetic basis of Fanconi anemia.Curr Opin Hematol2003
12882984Nucleophosmin interacts with and inhibits the catalytic function of eukaryotic initiation factor 2 kinase PKR.J Biol Chem2003
12637330Acquired FANCA dysfunction and cytogenetic instability in adult acute myelogenous leukemia.Blood2003
12724761Cisplatin and the sensitive cell.Nat Med2003
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Collaborators

Brian J Druker
Oregon Health & Science University
Co-authored papers 5
Jeffrey W Tyner
Oregon Health & Science University School of Medicine
Co-authored papers 5
Anupriya Agarwal
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 4
Pavana Anur
Oregon Health & Science University
Co-authored papers 4
Laura F Newell
Oregon Health and Science University
Co-authored papers 4
Kim-Hien T Dao
Astex Pharmaceuticals
Co-authored papers 3
Thomas G DeLoughery
Oregon Health & Science University
Co-authored papers 3
Richard D Press
Oregon Health and Science University
Co-authored papers 3
Gabrielle Meyers
Oregon Health and Science University
Co-authored papers 3
Jay A Nelson
Oregon Health and Science University
Co-authored papers 3
Yassmine Akkari
Association for Molecular Pathology
Co-authored papers 3
Robert M Bennett
Fibromyalgia Research Unit, Oregon Health & Science University
Co-authored papers 3
Elie Traer
Oregon Health & Science University
Co-authored papers 2
Jean Soulier
University of Paris
Co-authored papers 2
Angela G Fleischman
University of California Irvine
Co-authored papers 2
Tanja Pejovic
Oregon Health & Science University
Co-authored papers 2
Christina A Harrington
Oregon Health & Science University
Co-authored papers 2
Kevin P Battaile
Co-authored papers 2
Jennifer Dunlap
Oregon Health & Science University
Co-authored papers 2
Richard T Maziarz
Oregon Health & Science University
Co-authored papers 2
Shannon K McWeeney
Oregon Health & Science University, University of California Berkeley
Co-authored papers 2
Alan D D'Andrea
Dana-Farber Cancer Institute
Co-authored papers 2
Michael W Deininger
University of Utah Huntsman Cancer Institute
Co-authored papers 2
Arleen D Auerbach
The Rockefeller University
Co-authored papers 2
William H Fleming
Oregon Health & Science University
Co-authored papers 2
Charles R Leemans
Location Vrije Universiteit Amsterdam
Co-authored papers 1
Marc M Loriaux
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 1
Kavin B Vasudevan
Knight Cancer Institute, Oregon Health & Science University
Co-authored papers 1
Robert L Strausberg
Ludwig Institute for Cancer Research
Co-authored papers 1
Hyunjung Lee
Oregon Health & Science University, Knight Cancer Institute
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Release 1.2