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Author Details

Alexander A Vinks
Cincinnati Children's Hospital Medical Center
1982
264
47
PMIDPaper TitleJournal TitlePublished Year
36031093Multicenter Cohort Study of Infliximab Pharmacokinetics and Therapy Response in Pediatric Acute Severe Ulcerative Colitis.Clin Gastroenterol Hepatol2023
38018175Rationale, Development, and Validation of HdxSim, a Clinical Decision Support Tool for Model-Informed Precision Dosing of Hydroxyurea for Children with Sickle Cell Anemia.Clin Pharmacol Ther2023
37594205Novel Therapeutic Modalities: The Future is Now.Clin Pharmacol Ther2023
37771190Tutorial on model selection and validation of model input into precision dosing software for model-informed precision dosing.CPT Pharmacometrics Syst Pharmacol2023
37725684Ceftriaxone Pharmacokinetics and Pharmacodynamics in 2 Pediatric Patients on Extracorporeal Membrane Oxygenation Therapy.Ther Drug Monit2023
37325474Hydroxyurea pharmacokinetics and precision dosing in low-resource settings.Front Mol Biosci2023
37387481Adopting Model-Informed Precision-Dosing for Eculizumab in Transplant Associated-Thrombotic Microangiopathy to Gene Therapies.Clin Pharmacol Ther2023
37316457Model-Informed Precision Dosing Guidance of Ethosuximide Developed from a Randomized Controlled Clinical Trial of Childhood Absence Epilepsy.Clin Pharmacol Ther2023
37466170Cefepime pharmacokinetics in critically ill children and young adults undergoing continuous kidney replacement therapy.J Antimicrob Chemother2023
36545869Relationship between piperacillin concentrations, clinical factors and piperacillin/tazobactam-associated acute kidney injury.J Antimicrob Chemother2023
36715063Implementation of CYP2D6-guided opioid therapy at Cincinnati Children's Hospital Medical Center.Am J Health Syst Pharm2023
36728342Model-Informed Estimation of Acutely Decreased Tacrolimus Clearance and Subsequent Dose Individualization in a Pediatric Renal Transplant Patient With Posterior Reversible Encephalopathy Syndrome.Ther Drug Monit2023
36413113Model-informed Precision Dosing for Biologics Is Now Available at the Bedside for Patients With Inflammatory Bowel Disease.Inflamm Bowel Dis2023
36928875Hydroxyurea treatment for sickle cell anemia during pregnancy and lactation: Current evidence and knowledge gaps.Pharmacotherapy2023
36727212Pharmacokinetic parameters over time during sepsis and the association of target attainment and outcomes in critically ill children and young adults receiving ceftriaxone.Pharmacotherapy2023
36314265Real world population pharmacokinetic study in children and young adults with inflammatory bowel disease discovers novel blood and stool microbial predictors of vedolizumab clearance.Aliment Pharmacol Ther2023
32529759Clinical implementation of pharmacogenetics and model-informed precision dosing to improve patient care.Br J Clin Pharmacol2022
36532752β-lactam precision dosing in critically ill children: Current state and knowledge gaps.Front Pharmacol2022
33689087Low-dose Dasatinib Ameliorates Hypertrophic Cardiomyopathy in Noonan Syndrome with Multiple Lentigines.Cardiovasc Drugs Ther2022
35008105Eculizumab precision-dosing algorithm for thrombotic microangiopathy in children and young adults undergoing HSCT.Blood Adv2022
34935161Antibodies-to-infliximab accelerate clearance while dose intensification reverses immunogenicity and recaptures clinical response in paediatric Crohn's disease.Aliment Pharmacol Ther2022
34813863A review of pregnancy-induced changes in opioid pharmacokinetics, placental transfer, and fetal exposure: Towards fetomaternal physiologically-based pharmacokinetic modeling to improve the treatment of neonatal opioid withdrawal syndrome.Pharmacol Ther2022
34633847Population Pharmacokinetic Modeling of Total and Free Ceftriaxone in Critically Ill Children and Young Adults and Monte Carlo Simulations Support Twice Daily Dosing for Target Attainment.Antimicrob Agents Chemother2022
34679189Physiologically-Based Pharmacokinetic Modeling to Investigate the Effect of Maturation on Buprenorphine Pharmacokinetics in Newborns with Neonatal Opioid Withdrawal Syndrome.Clin Pharmacol Ther2022
34075614Test-dose pharmacokinetics guided melphalan dose adjustment in reduced intensity conditioning allogeneic transplant for non-malignant disorders.Br J Clin Pharmacol2022
34182590Model-informed precision dosing for alemtuzumab in paediatric and young adult patients undergoing allogeneic haematopoietic cell transplantation.Br J Clin Pharmacol2022
32118552Methodologic Progress Note: Opportunistic Sampling for Pharmacology Studies in Hospitalized Children.J Hosp Med2021
33711005Personalized Therapy for Mycophenolate: Consensus Report by the International Association of Therapeutic Drug Monitoring and Clinical Toxicology.Ther Drug Monit2021
33507822NF106: A Neurofibromatosis Clinical Trials Consortium Phase II Trial of the MEK Inhibitor Mirdametinib (PD-0325901) in Adolescents and Adults With NF1-Related Plexiform Neurofibromas.J Clin Oncol2021
33616919Roger W. Jelliffe, MD, FCP, FAAPS: A World Leader in Population Pharmacokinetic and Pharmacodynamic Modeling and Model-Based Target Controlled Individualized Dosing.Clin Pharmacol Ther2021
33616906Precision Dosing: The Clinical Pharmacology of Goldilocks.Clin Pharmacol Ther2021
33534136Hydroyxurea improves cerebral oxygen saturation in children with sickle cell anemia.Am J Hematol2021
33582807Paperspray Ionization Mass Spectrometry as a Tool for Predicting Real-Time Optimized Dosing of the Chemotherapeutic Drug Melphalan.J Appl Lab Med2021
34379758Pharmacokinetic modelling to predict risk of ototoxicity with intravenous tobramycin treatment in cystic fibrosis.J Antimicrob Chemother2021
34548626A prospective pilot study of a novel alemtuzumab target concentration intervention strategy.Bone Marrow Transplant2021
34654029Therapeutic Drug Monitoring in the Era of Precision Medicine: Achievements, Gaps, and Perspectives-An Interview in Honor of Professor Charles Pippenger.Ther Drug Monit2021
34185896Status Toward the Implementation of Precision Dosing in Children.J Clin Pharmacol2021
34185897Model-Informed Pediatric Drug Development: Application of Pharmacometrics to Define the Right Dose for Children.J Clin Pharmacol2021
34311506Machine Learning as a Novel Method to Support Therapeutic Drug Management and Precision Dosing.Clin Pharmacol Ther2021
34227124Early initiation of hydroxyurea (hydroxycarbamide) using individualised, pharmacokinetics-guided dosing can produce sustained and nearly pancellular expression of fetal haemoglobin in children with sickle cell anaemia.Br J Haematol2021
33316689Sirolimus Treatment in Sturge-Weber Syndrome.Pediatr Neurol2021
33140540A POETIC Phase II study of continuous oral everolimus in recurrent, radiographically progressive pediatric low-grade glioma.Pediatr Blood Cancer2021
33111331Demonstrating Feasibility of an Opportunistic Sampling Approach for Pharmacokinetic Studies of β-Lactam Antibiotics in Critically Ill Children.J Clin Pharmacol2021
33029796Hydroxyurea Pharmacokinetics in Pediatric Patients After Total Pancreatectomy With Islet Autotransplantation.J Clin Pharmacol2021
33049155Pharmacotherapy of neonatal opioid withdrawal syndrome: a review of pharmacokinetics and pharmacodynamics.Expert Opin Drug Metab Toxicol2021
33354765Real-World Infliximab Pharmacokinetic Study Informs an Electronic Health Record-Embedded Dashboard to Guide Precision Dosing in Children with Crohn's Disease.Clin Pharmacol Ther2021
33382111Opioid Treatment for Neonatal Opioid Withdrawal Syndrome: Current Challenges and Future Approaches.J Clin Pharmacol2021
33201535A Pilot Randomized, Controlled, Double-Blind Trial of Bumetanide to Treat Neonatal Seizures.Ann Neurol2021
32939690Physiologic Indirect Response Modeling to Describe Buprenorphine Pharmacodynamics in Newborns Treated for Neonatal Opioid Withdrawal Syndrome.Clin Pharmacokinet2021
31618453Electronic Health Record-Embedded Decision Support Platform for Morphine Precision Dosing in Neonates.Clin Pharmacol Ther2020
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Collaborators

University of Pittsburgh Medical Center
Co-authored papers 21
Cincinnati Children's Hospital Medical Center, University of Cincinnati
Co-authored papers 11
Cincinnati Children's Hospital Medical Center
Co-authored papers 8
Co-authored papers 7
Co-authored papers 7
Cincinnati Children's Hospital Medical Center
Co-authored papers 5
Cincinnati Children's Hospital Medical Center
Co-authored papers 5
Cancer & Blood Diseases Institute, Cincinnati Children's Hospital Medical Center
Co-authored papers 4
Cincinnati Children's Hospital Medical Center
Co-authored papers 4
Brain Tumor Institute, Children's National Hospital
Co-authored papers 4
Nationwide Children's Hospital
Co-authored papers 4
Co-authored papers 4
Cincinnati Children's Hospital Medical Center
Co-authored papers 3
Co-authored papers 3
Co-authored papers 3
University of Cincinnati College of Medicine
Co-authored papers 3
Vanderbilt University Medical Center
Co-authored papers 2
University of Alabama at Birmingham
Co-authored papers 2
Center for Acute Care Nephrology, Cincinnati Children's Hospital
Co-authored papers 2
Co-authored papers 2
Montefiore Medical Center, Albert Einstein College of Medicine
Co-authored papers 2
Co-authored papers 2
George Washington University
Co-authored papers 2
Co-authored papers 2
Boston Children's Hospital and Harvard Medical School
Co-authored papers 2
University of Alabama Birmingham
Co-authored papers 1
University of Washington.
Co-authored papers 1
The University of Texas Health Science Center at San Antonio
Co-authored papers 1
University of Colorado School of Medicine
Co-authored papers 1
The Children's Hospital of Philadelphia, University of Pennsylvania
Co-authored papers 1