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Author Details

Daniel J McGrail
Center for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic
2012
62
23
PMIDPaper TitleJournal TitlePublished Year
36265133Landscape of MicroRNA Regulatory Network Architecture and Functional Rerouting in Cancer.Cancer Res2023
37527013SETD2 Loss and ATR Inhibition Synergize to Promote cGAS Signaling and Immunotherapy Response in Renal Cell Carcinoma.Clin Cancer Res2023
37909041Widespread BRCA1/2-independent homologous recombination defects are caused by alterations in RNA-binding proteins.Cell Rep Med2023
37907220Cytosolic DNA accumulation promotes breast cancer immunogenicity via a STING-independent pathway.J Immunother Cancer2023
37540752Multiomics analyses reveal <i>DARS1-AS1</i>/YBX1-controlled posttranscriptional circuits promoting glioblastoma tumorigenesis/radioresistance.Sci Adv2023
37770423Defining the condensate landscape of fusion oncoproteins.Nat Commun2023
37637041Radiographic response to neoadjuvant therapy in pleural mesothelioma should serve as a guide for patient selection for cytoreductive operations.Front Oncol2023
37256648Spatial Immunoprofiling of Adenoid Cystic Carcinoma Reveals B7-H4 Is a Therapeutic Target for Aggressive Tumors.Clin Cancer Res2023
37449360Correction: Proteogenomic Analysis of Salivary Adenoid Cystic Carcinomas Defines Molecular Subtypes and Identifies Therapeutic Targets.Clin Cancer Res2023
36647828Immune checkpoint blockade in glioblastoma: from tumor heterogeneity to personalized treatment.J Clin Invest2023
34653632Distinct tumor-infiltrating lymphocyte landscapes are associated with clinical outcomes in localized non-small-cell lung cancer.Ann Oncol2022
35852417Biomolecular Condensation: A New Phase in Cancer Research.Cancer Discov2022
36518525Single-cell CRISPR immune screens reveal immunological roles of tumor intrinsic factors.NAR Cancer2022
35926816Validation of cancer-type-dependent benefit from immune checkpoint blockade in TMB-H tumors identified by the FoundationOne CDx assay.Ann Oncol2022
35944232Shared Nearest Neighbors Approach and Interactive Browser for Network Analysis of a Comprehensive Non-Small-Cell Lung Cancer Data Set.JCO Clin Cancer Inform2022
35038676Surgical approach does not influence changes in circulating immune cell populations following lung cancer resection.Lung Cancer2022
35212000Dermal αSMA<sup>+</sup> myofibroblasts orchestrate skin wound repair via β1 integrin and independent of type I collagen production.EMBO J2022
35241495Spontaneous tumor regression following COVID-19 vaccination.J Immunother Cancer2022
35141022Exploiting induced vulnerability to overcome PARPi resistance and clonal heterogeneity in BRCA mutant triple-negative inflammatory breast cancer.Am J Cancer Res2022
35110355Combined IL-2, agonistic CD3 and 4-1BB stimulation preserve clonotype hierarchy in propagated non-small cell lung cancer tumor-infiltrating lymphocytes.J Immunother Cancer2022
33096269Neoadjuvant Chemotherapy Increases Cytotoxic T Cell, Tissue Resident Memory T Cell, and B Cell Infiltration in Resectable NSCLC.J Thorac Oncol2021
33736924High tumor mutation burden fails to predict immune checkpoint blockade response across all cancer types.Ann Oncol2021
34705519Replication stress response defects are associated with response to immune checkpoint blockade in nonhypermutated cancers.Sci Transl Med2021
34799452PD-L1 sustains chronic, cancer cell-intrinsic responses to type I interferon, enhancing resistance to DNA damage.Proc Natl Acad Sci U S A2021
34066883A Gene Expression Signature to Predict Nucleotide Excision Repair Defects and Novel Therapeutic Approaches.Int J Mol Sci2021
34166757Reply to: 'Real-world prevalence across 159 872 patients with cancer supports the clinical utility of TMB-H to define metastatic solid tumors for treatment with pembrolizumab.' by D. Fabrizio et al.Ann Oncol2021
33947685Combined Inhibition of Rad51 and Wee1 Enhances Cell Killing in HNSCC Through Induction of Apoptosis Associated With Excessive DNA Damage and Replication Stress.Mol Cancer Ther2021
33172898Proteogenomic Analysis of Salivary Adenoid Cystic Carcinomas Defines Molecular Subtypes and Identifies Therapeutic Targets.Clin Cancer Res2021
33211847e-MutPath: computational modeling reveals the functional landscape of genetic mutations rewiring interactome networks.Nucleic Acids Res2021
33388477Characterization of the Immune Landscape of EGFR-Mutant NSCLC Identifies CD73/Adenosine Pathway as a Potential Therapeutic Target.J Thorac Oncol2021
29738884Pathway perturbations in signaling networks: Linking genotype to phenotype.Semin Cell Dev Biol2020
32051231Nucleostemin Modulates Outcomes of Hepatocellular Carcinoma via a Tumor Adaptive Mechanism to Genomic Stress.Mol Cancer Res2020
33110184Protection against SARS-CoV-2 by BCG vaccination is not supported by epidemiological analyses.Sci Rep2020
32855206Integrated Genomic Characterization of the Human Immunome in Cancer.Cancer Res2020
32730356Enacting national social distancing policies corresponds with dramatic reduction in COVID19 infection rates.PLoS One2020
32358509PBRM1 loss defines a nonimmunogenic tumor phenotype associated with checkpoint inhibitor resistance in renal carcinoma.Nat Commun2020
32109374Proteome Instability Is a Therapeutic Vulnerability in Mismatch Repair-Deficient Cancer.Cancer Cell2020
30692636Nucleostemin reveals a dichotomous nature of genome maintenance in mammary tumor progression.Oncogene2019
30153342MERIT: Systematic Analysis and Characterization of Mutational Effect on RNA Interactome Topology.Hepatology2019
30152517PARP inhibitors synergize with gemcitabine by potentiating DNA damage in non-small-cell lung cancer.Int J Cancer2019
31185210Sequential Therapy with PARP and WEE1 Inhibitors Minimizes Toxicity while Maintaining Efficacy.Cancer Cell2019
29768207Defective Replication Stress Response Is Inherently Linked to the Cancer Stem Cell Phenotype.Cell Rep2018
29941230Gene Regulatory Network Perturbation by Genetic and Epigenetic Variation.Trends Biochem Sci2018
29888111CHD4 mutations promote endometrial cancer stemness by activating TGF-beta signaling.Am J Cancer Res2018
29615613Multi-omics analysis reveals neoantigen-independent immune cell infiltration in copy-number driven cancers.Nat Commun2018
28649435Improved prediction of PARP inhibitor response and identification of synergizing agents through use of a novel gene expression signature generation algorithm.NPJ Syst Biol Appl2017
28439535A murine preclinical syngeneic transplantation model for breast cancer precision medicine.Sci Adv2017
28421182TGF-β1 Pretreatment Improves the Function of Mesenchymal Stem Cells in the Wound Bed.Front Cell Dev Biol2017
29045845Revealing the Determinants of Widespread Alternative Splicing Perturbation in Cancer.Cell Rep2017
25491311SNAIL-induced epithelial-to-mesenchymal transition produces concerted biophysical changes from altered cytoskeletal gene expression.FASEB J2015
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Collaborators

Shiaw-Yih Lin
The University of Texas MD Anderson Cancer Center
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The University of Texas MD Anderson Cancer Center
Co-authored papers 16
Gordon B Mills
Knight Cancer Institute, Oregon Health and Sciences University
Co-authored papers 12
Yongsheng Li
Harbin Medical University
Co-authored papers 8
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The University of Texas MD Anderson Cancer Center
Co-authored papers 6
Song Yi
Livestrong Cancer Institutes, Dell Medical School, The University of Texas at Austin
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Jianhua Zhang
University of Texas MD Anderson Cancer Center
Co-authored papers 5
Amy B Heimberger
Northwestern University Feinberg School of Medicine
Co-authored papers 5
Phillip A Futreal
The University of Texas MD Anderson Cancer Center
Co-authored papers 5
Lixia Diao
The University of Texas MD Anderson Cancer Center
Co-authored papers 4
Yiling Lu
Co-authored papers 4
Adel K El-Naggar
MD Anderson Cancer Center
Co-authored papers 3
Christine B Peterson
University of Texas MD Anderson Cancer Center
Co-authored papers 3
David J H Shih
University of Texas MD Anderson Cancer Center Houston
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Erxi Wu
Livestrong Cancer Institutes, Dell Medical School, The University of Texas at Austin
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Juan Xu
College of Bioinformatics Science and Technology, Harbin Medical University
Co-authored papers 3
Zhenlin Ju
Co-authored papers 3
Naoto T Ueno
Cancer Research Center of Hawaii: University of Hawai'i Cancer Center.
Co-authored papers 2
Limei Hu
Aier Eye Hospital of Wuhan University
Co-authored papers 2
Jeannine Garnett
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
Rita Pancsa
Institute of Enzymology, HUN-REN Research Centre for Natural Sciences
Co-authored papers 2
John F McDonald
Georgia Institute of Technology
Co-authored papers 2
Madan Mohan Babu
St. Jude Children's Research Hospital
Co-authored papers 2
Xingzhi Song
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
Ken Chen
University of Texas MD Anderson Cancer Center
Co-authored papers 2
Adam M Sonabend
Northwestern University
Co-authored papers 1
Yunyun Zhou
Children's Hospital of Philadelphia
Co-authored papers 1
Wenjin Jim Zheng
University of Texas Health Science Center at Houston
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Frederick F Lang
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