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Author Details

Inge M Ambros
St. Anna Children's Cancer Research Institute
1990
88
35
Nathan Sheffield (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
34623519Comparison of three different methods to detect bone marrow involvement in patients with neuroblastoma.J Cancer Res Clin Oncol2022
35859155Amplification of CDK4 and MDM2: a detailed study of a high-risk neuroblastoma subgroup.Sci Rep2022
36054432Human repair-related Schwann cells adopt functions of antigen-presenting cells in vitro.Glia2022
34050156Multimodal analysis of cell-free DNA whole-genome sequencing for pediatric cancers with low mutational burden.Nat Commun2021
33712610Schwann cell plasticity regulates neuroblastic tumor cell differentiation via epidermal growth factor-like protein 8.Nat Commun2021
33540616Long-Term Outcome and Role of Biology within Risk-Adapted Treatment Strategies: The Austrian Neuroblastoma Trial A-NB94.Cancers (Basel)2021
33784615Evaluation of Deep Learning Architectures for Complex Immunofluorescence Nuclear Image Segmentation.IEEE Trans Med Imaging2021
34815394Spatial and temporal intratumour heterogeneity has potential consequences for single biopsy-based neuroblastoma treatment decisions.Nat Commun2021
34503120Landscape of Bone Marrow Metastasis in Human Neuroblastoma Unraveled by Transcriptomics and Deep Multiplex Imaging.Cancers (Basel)2021
32497717Assessment of Pre-Analytical Sample Handling Conditions for Comprehensive Liquid Biopsy Analysis.J Mol Diagn2020
32903140Age Dependency of the Prognostic Impact of Tumor Genomics in Localized Resectable <i>MYCN</i>-Nonamplified Neuroblastomas. Report From the SIOPEN Biology Group on the LNESG Trials and a COG Validation Group.J Clin Oncol2020
32782410An annotated fluorescence image dataset for training nuclear segmentation methods.Sci Data2020
30585743DeepSNP: An End-to-End Deep Neural Network with Attention-Based Localization for Breakpoint Detection in Single-Nucleotide Polymorphism Array Genomic Data.J Comput Biol2019
28921546Neuroblastoma cells undergo transcriptomic alterations upon dissemination into the bone marrow and subsequent tumor progression.Int J Cancer2018
29755120Heterogeneous MYCN amplification in neuroblastoma: a SIOP Europe Neuroblastoma Study.Br J Cancer2018
29546701Detailed Protocols for the Isolation, Culture, Enrichment and Immunostaining of Primary Human Schwann Cells.Methods Mol Biol2018
29514301Genomic Amplifications and Distal 6q Loss: Novel Markers for Poor Survival in High-risk Neuroblastoma Patients.J Natl Cancer Inst2018
28134926DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma.Nat Med2017
28228384Impact of Disseminated Neuroblastoma Cells on the Identification of the Relapse-Seeding Clone.Clin Cancer Res2017
26119945Comparative genetic study of intratumoral heterogenous MYCN amplified neuroblastoma versus aggressive genetic profile neuroblastic tumors.Oncogene2016
26657295Metronomic topotecan impedes tumor growth of MYCN-amplified neuroblastoma cells in vitro and in vivo by therapy induced senescence.Oncotarget2016
27560999Tumor Touch Imprints as Source for Whole Genome Analysis of Neuroblastoma Tumors.PLoS One2016
27550150Chromosome 1q gain and tenascin-C expression are candidate markers to define different risk groups in pediatric posterior fossa ependymoma.Acta Neuropathol Commun2016
27545331Proteomics and transcriptomics of peripheral nerve tissue and cells unravel new aspects of the human Schwann cell repair phenotype.Glia2016
26910568The genetic tumor background is an important determinant for heterogeneous MYCN-amplified neuroblastoma.Int J Cancer2016
25356804Influence of segmental chromosome abnormalities on survival in children over the age of 12 months with unresectable localised peripheral neuroblastic tumours without MYCN amplification.Br J Cancer2015
25467309Bone marrows from neuroblastoma patients: an excellent source for tumor genome analyses.Mol Oncol2015
25161957Ultra-High Density SNParray in Neuroblastoma Molecular Diagnostics.Front Oncol2014
22976801Segmental chromosomal alterations have prognostic impact in neuroblastoma: a report from the INRG project.Br J Cancer2012
21325297A multilocus technique for risk evaluation of patients with neuroblastoma.Clin Cancer Res2011
22146831Segmental chromosomal alterations lead to a higher risk of relapse in infants with MYCN-non-amplified localised unresectable/disseminated neuroblastoma (a SIOPEN collaborative study).Br J Cancer2011
21533183DNA damage, somatic aneuploidy, and malignant sarcoma susceptibility in muscular dystrophies.PLoS Genet2011
19489051Free DNA in the blood serum can unmask MYCN amplified tumors.Pediatr Blood Cancer2009
19401703International consensus for neuroblastoma molecular diagnostics: report from the International Neuroblastoma Risk Group (INRG) Biology Committee.Br J Cancer2009
16732582Diagnostic and prognostic impact of urinary catecholamines in neuroblastoma patients.Pediatr Blood Cancer2007
18158560Pathology of peripheral neuroblastic tumors: significance of prominent nucleoli in undifferentiated/poorly differentiated neuroblastoma.Pathol Oncol Res2007
17106870Induction of senescence in MYCN amplified neuroblastoma cell lines by hydroxyurea.Genes Chromosomes Cancer2007
16849741Treatment complications in neuroblastoma patients: lessons from screening studies.J Clin Oncol2006
17063089Immunohistochemical analysis of INI1 protein in malignant pediatric CNS tumors: Lack of INI1 in atypical teratoid/rhabdoid tumors and in a fraction of primitive neuroectodermal tumors without rhabdoid phenotype.Am J Surg Pathol2006
16136500DEC1 expression in 1p-aberrant oligodendroglial neoplasms.Histol Histopathol2005
15475445Expression of hypoxia-related tissue factors correlates with diminished survival of adjuvantly treated patients with chromosome 1p aberrant oligodendroglial neoplasms and therapeutic implications.Clin Cancer Res2004
12861068Fluorescent in situ hybridization on isolated tumor cell nuclei: a sensitive method for 1p and 19q deletion analysis in paraffin-embedded oligodendroglial tumor specimens.Mod Pathol2003
12880956Disseminated tumor cells in the bone marrow - chances and consequences of microscopical detection methods.Cancer Lett2003
12875961Detection of disseminated tumor cells in neuroblastoma: 3 log improvement in sensitivity by automatic immunofluorescence plus FISH (AIPF) analysis compared with classical bone marrow cytology.Am J Pathol2003
14615452Neuroblastoma mass screening in late infancy: insights into the biology of neuroblastic tumors.J Clin Oncol2003
12744467Vascular patterns in glioblastoma influence clinical outcome and associate with variable expression of angiogenic proteins: evidence for distinct angiogenic subtypes.Brain Pathol2003
12775732Quality assessment of genetic markers used for therapy stratification.J Clin Oncol2003
11813175Neuroblastoma with focal MYCN amplification and bone marrow infiltration: a staging and treatment dilemma.Med Pediatr Oncol2002
12149507Frequent low level expression in Ewing sarcoma family tumors and widespread absence of the metastasis suppressor KAI1/CD82 in neuroblastoma.Pediatr Res2002
12506762[Detection, quantification and characterization of disseminated tumor cells].Acta Med Austriaca Suppl2002
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Collaborators

Children's Cancer Research Institute, Medical University of Vienna
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St. Anna Children's Cancer Research Institute
Co-authored papers 14
St. Anna Children's Cancer Research Institute (CCRI), Medical University Vienna
Co-authored papers 10
Institut Curie
Co-authored papers 8
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Co-authored papers 6
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Co-authored papers 5
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Co-authored papers 5
PSL Research University, Institut Curie Research Center, INSERM U, Institut Curie
Co-authored papers 5
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Co-authored papers 4
Children's Hospital of Philadelphia
Co-authored papers 3
Institut Curie
Co-authored papers 3
Institut Curie Hospital
Co-authored papers 3
Memorial Sloan Kettering Cancer Center
Co-authored papers 3
Children's Cancer Research Institute, Medical University of Vienna
Co-authored papers 3
University of Oxford
Co-authored papers 3
University Children's Hospital of Cologne
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Children's Cancer Research Institute
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St. Anna Children's Cancer Research Institute (CCRI)
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Children's Cancer Research Institute
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CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
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Medical University of Vienna
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St. Anna Children's Cancer Research Institute (CCRI)
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St. Anna Children's Cancer Research Institute (CCRI)
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Balgrist University Hospital, University of Zurich (UZH)
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University of Virginia
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