Author details

Full Name

Ruth McPherson

Affiliation

ORCID

Career Start Year

1985

Papers

268

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37291259	Regulation of TRIB1 abundance in hepatocyte models in response to proteasome inhibition.		2023
35130031	Common Polymorphism That Protects From Cardiovascular Disease Increases Fibronectin Processing and Secretion.	Circulation. Genomic and precision medicine	2022
35965199	Exercise training enhances muscle mitochondrial metabolism in diet-resistant obesity.	EBioMedicine	2022
36035741	Profound Elevation in LDL Cholesterol Level Following a Ketogenic Diet: A Case Series.	CJC Open	2022
35892309	Targeting skeletal muscle mitochondrial health in obesity.	Clin Sci (Lond)	2022
35381443	A novel anti-inflammatory role links the CARS2 locus to protection from coronary artery disease.	Atherosclerosis	2022
35852134	Genome-wide screening identifies DNA methylation sites that regulate the blood proteome.	Epigenomics	2022
35306566	Genetically Determined Reproductive Aging and Coronary Heart Disease: A Bidirectional 2-sample Mendelian Randomization.	J Clin Endocrinol Metab	2022
35293095	Association of muscle fiber type with measures of obesity: A systematic review.	Obes Rev	2022
34418482	Colchicine for Prevention of Atherothrombotic Events in Patients With Coronary Artery Disease: Review and Practical Approach for Clinicians.	Can J Cardiol	2021
33574266	Convergence of biomarkers and risk factor trait loci of coronary artery disease at 3p21.31 and HLA region.	npj Genomic Medicine	2021
33781847	2021 Canadian Cardiovascular Society Guidelines for the Management of Dyslipidemia for the Prevention of Cardiovascular Disease in Adults.	Canadian Journal of Cardiology	2021
34207686	Epigenome-Wide Study Identified Methylation Sites Associated with the Risk of Obesity.	Nutrients	2021
33822779	Correction: A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease.	PLoS Genet	2021
34134519	A Common Polymorphism in the Locus Links miR1908 to Low-Density Lipoprotein Cholesterol Through BMP1.	Arteriosclerosis, Thrombosis, and Vascular Biology	2021
34337661	Interindividual variability in weight loss in the treatment of obesity.	Am J Clin Nutr	2021
34887471	miR1908-5p regulates energy homeostasis in hepatocyte models.	Scientific Reports	2021
32625236	Is a Long Non-coding RNA Locus That Regulates Expression.	Frontiers in Genetics	2020
32654539	Association of Factor V Leiden With Subsequent Atherothrombotic Events: A GENIUS-CHD Study of Individual Participant Data.	Circulation	2020
32989316	RIPK1 gene variants associate with obesity in humans and can be therapeutically silenced to reduce obesity in mice.	Nat Metab	2020
33035570	Factors affecting weight loss variability in obesity.	Metabolism	2020
33033401	Publisher Correction: RIPK1 gene variants associate with obesity in humans and can be therapeutically silenced to reduce obesity in mice.	Nat Metab	2020
32585424	Molecular mechanism linking a novel PCSK9 copy number variant to severe hypercholesterolemia.	Atherosclerosis	2020
32527767	<i>SGCG</i> rs679482 Associates With Weight Loss Success in Response to an Intensively Supervised Outpatient Program.	Diabetes	2020
32969717	Multiomics Screening Identifies Molecular Biomarkers Causally Associated With the Risk of Coronary Artery Disease.	Circulation. Genomic and precision medicine	2020
32862661	Heterozygous <i>ABCG5</i> Gene Deficiency and Risk of Coronary Artery Disease.	Circ Genom Precis Med	2020
31462092	2018 George Lyman Duff Memorial Lecture: Genetics and Genomics of Coronary Artery Disease: A Decade of Progress.	Arteriosclerosis, Thrombosis, and Vascular Biology	2019
31658298	Off-target effects of CRISPRa on interleukin-6 expression.	PLoS ONE	2019
30389748	DNA Sequence Variation in <i>ACVR1C</i> Encoding the Activin Receptor-Like Kinase 7 Influences Body Fat Distribution and Protects Against Type 2 Diabetes.	Diabetes	2019
30861420	Regulation of MFGE8 by the intergenic coronary artery disease locus on 15q26.1.	Atherosclerosis	2019
31164165	The selective peroxisome proliferator-activated receptor alpha modulator (SPPARMÎ±) paradigm: conceptual framework and therapeutic potential : A consensus statement from the International Atherosclerosis Society (IAS) and the Residual Risk Reduction Initia	Cardiovascular Diabetology	2019
30897348	Association of Chromosome 9p21 With Subsequent Coronary Heart Disease Events.	Circ Genom Precis Med	2019
30715214	Genome-wide identification of circulating-miRNA expression quantitative trait loci reveals the role of several miRNAs in the regulation of cardiometabolic phenotypes.	Cardiovasc Res	2019
29151592	Diet-resistant obesity is characterized by a distinct plasma proteomic signature and impaired muscle fiber metabolism.	Int J Obes (Lond)	2018
28982690	Phenotypic Consequences of a Genetic Predisposition to Enhanced Nitric Oxide Signaling.	Circulation	2018
28800932	Is Type 2 Diabetes in Adults Associated With Impaired Capacity for Weight Loss?	Can J Diabetes	2018
30269829	Whole-Gene Duplication of PCSK9 as a Novel Genetic Mechanism for Severe Familial Hypercholesterolemia.	Canadian Journal of Cardiology	2018
30451909	Obesity shows preserved plasma proteome in large independent clinical cohorts.	Sci Rep	2018
30093301	The Cardiovascular Burden of Undiagnosed Familial Hypercholesterolemia: Need to Modify Guidelines to Encourage Earlier Diagnosis and Therapy.	Canadian Journal of Cardiology	2018
29444804	Partitioning the Pleiotropy Between Coronary Artery Disease and Body Mass Index Reveals the Importance of Low Frequency Variants and Central Nervous System-Specific Functional Elements.	Circulation. Genomic and precision medicine	2018
29691411	Analysis of predicted loss-of-function variants in UK Biobank identifies variants protective for disease.	Nat Commun	2018
28115489	Functional Validation of a Common Nonsynonymous Coding Variant in ZC3HC1 Associated With Protection From Coronary Artery Disease.	Circulation: Cardiovascular Genetics	2017
28506971	Protein-Truncating Variants at the Cholesteryl Ester Transfer Protein Gene and Risk for Coronary Heart Disease.	Circ Res	2017
28461624	Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions.	Circulation	2017
28717196	TRIB1 is a positive regulator of hepatocyte nuclear factor 4-alpha.	Scientific Reports	2017
28714975	Association analyses based on false discovery rate implicate new loci for coronary artery disease.	Nat Genet	2017
28566218	Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study.	Lancet Diabetes Endocrinol	2017
28267856	Association of Rare and Common Variation in the Lipoprotein Lipase Gene With Coronary Artery Disease.	JAMA	2017
28158393	Partitioning the heritability of coronary artery disease highlights the importance of immune-mediated processes and epigenetic sites associated with transcriptional activity.	Cardiovascular Research	2017
28209224	Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated WithÂ Coronary ArteryÂ Disease.	J Am Coll Cardiol	2017