Author details

Full Name

Sin Man Lam

Affiliation

ORCID

Career Start Year

2011

Papers

117

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36847607	Saturated fatty acids increase LPI to reduce FUNDC1 dimerization and stability and mitochondrial function.	EMBO Rep	2023
38036537	Skeletal muscle-secreted DLPC orchestrates systemic energy homeostasis by enhancing adipose browning.		2023
37794463	Ceramide d18:1/24:1 as a potential biomarker to differentiate obesity subtypes with unfavorable health outcomes.		2023
37555936	Adipocyte Rnf20 ablation increases the fast-twitch fibers of skeletal muscle via lysophosphatidylcholine 16:0.		2023
37699389	Centrins control chicken cone cell lipid droplet dynamics through lipid-droplet-localized SPDL1.		2023
37616386	Multiomics Approaches Identify Biomarkers for BAT Thermogenesis.		2023
37867217	Maternal High Fat Diet in Lactation Impacts Hypothalamic Neurogenesis and Neurotrophic Development, Leading to Later Life Susceptibility to Obesity in Male but Not Female Mice.		2023
37773240	Multi-omics profiling reveals rhythmic liver function shaped by meal timing.		2023
37019081	Global determination of reaction rates and lipid turnover kinetics in Mus musculus.		2023
36933794	Phosphatidylcholine deficiency increases ferroptosis susceptibility in the Caenorhabditis elegans germline.		2023
36866528	Exendin-4 attenuates atherosclerosis progression via controlling hematopoietic stem/progenitor cell proliferation.		2023
37365376	Daytime-restricted feeding enhances running endurance without prior exercise in mice.		2023
37364711	Emerging roles and therapeutic potentials of sphingolipids in pathophysiology: Emphasis on fatty acyl heterogeneity.		2023
36727520	Precise Metabolomics Defines Systemic Metabolic Dysregulation Distinct to Acute Myocardial Infarction Associated With Diabetes.		2023
37538851	Differential effects of social isolation on oligodendrocyte development in different brain regions: insights from a canine model.		2023
37349354	The ER calcium channel Csg2 integrates sphingolipid metabolism with autophagy.		2023
35090093	Hepatic loss of CerS2 induces cell division defects via a mad2-mediated pathway.	Clinical and Translational Medicine	2022
35527334	Precise Metabolomics Reveals a Diversity of Aging-Associated Metabolic Features.	Small Methods	2022
35832080	Plasma lipids signify the progression of precancerous gastric lesions to gastric cancer: a prospective targeted lipidomics study.	Theranostics	2022
36224248	The purine metabolite inosine monophosphate accelerates myelopoiesis and acute pancreatitis progression.	Communications Biology	2022
35697672	Hsp90 induces Acsl4-dependent glioma ferroptosis via dephosphorylating Ser637 at Drp1.	Cell Death and Disease	2022
35572970	Metabolic Basis of Cognitive Improvement Associated With Active B Vitamin Supplementation in Cognitively Impaired Elderly Subjects - A Metabolomics Study.	Frontiers in Medicine	2022
35637196	GBA1-dependent membrane glucosylceramide reprogramming promotes liver cancer metastasis via activation of the Wnt/Î²-catenin signalling pathway.	Cell Death and Disease	2022
35613979	Neurological aspects of SARS-CoV-2 infection: lipoproteins and exosomes as Trojan horses.	Trends in Endocrinology and Metabolism	2022
35982909	Human promotes growth and metastasis via sphingolipid metabolite ceramide and PI4KA/AKT signaling in pancreatic cancer cells.	International Journal of Biological Sciences	2022
36117681	Circadian signatures of adipose tissue in diet-induced obesity.	Frontiers in Physiology	2022
36713590	Endogenous ceramide phosphoethanolamine modulates circadian rhythm via neural-glial coupling in .		2022
36546079	Hepatic CDP-diacylglycerol synthase 2 deficiency causes mitochondrial dysfunction and promotes rapid progression of NASH and fibrosis.	Sci Bull (Beijing)	2022
33740186	GM130 regulates pulmonary surfactant protein secretion in alveolar type II cells.	Science China Life Sciences	2022
35277964	Quantitative Lipidomics and Spatial MS-Imaging Uncovered Neurological and Systemic Lipid Metabolic Pathways Underlying Troglomorphic Adaptations in Cave-Dwelling Fish.	Molecular Biology and Evolution	2022
35235793	Activity-dependent PI4P synthesis by PI4KIIIÎ± regulates long-term synaptic potentiation.	Cell Reports	2022
34710622	Targeted lipidomics reveals plasmalogen phosphatidylethanolamines and storage triacylglycerols as the major systemic lipid aberrations in Bietti crystalline corneoretinal dystrophy.	Journal of Genetics and Genomics	2022
35128797	Constant light exposure alters gut microbiota and short-/medium-chain fatty acids and aggravates PCOS-like traits in HFD-fed rats.		2022
34705220	Dogs lacking Apolipoprotein E show advanced atherosclerosis leading to apparent clinical complications.	Science China Life Sciences	2022
34824276	AGPAT2 interaction with CDP-diacylglycerol synthases promotes the flux of fatty acids through the CDP-diacylglycerol pathway.	Nature Communications	2021
33592213	Targeted lipidomics reveals associations between serum sphingolipids and insulin sensitivity measured by the hyperinsulinemic-euglycemic clamp.	Diabetes Research and Clinical Practice	2021
33485579	High-coverage lipidomics for functional lipid and pathway analyses.	Analytica Chimica Acta	2021
33852853	Role of VAMP7-dependent secretion of reticulon 3 in neurite growth.	Cell Reports	2021
34158670	A multi-omics investigation of the composition and function of extracellular vesicles along the temporal trajectory of COVID-19.	Nature Metabolism	2021
33623033	Author Correction: Cryo-EM structure of trimeric Mycobacterium smegmatis succinate dehydrogenase with a membrane-anchor SdhF.	Nat Commun	2021
34103347	The Attenuation of Diabetic Nephropathy by Annexin A1 via Regulation of Lipid Metabolism Through the AMPK/PPARÎ±/CPT1b Pathway.		2021
33665933	The Unusual Homodimer of a Heme-Copper Terminal Oxidase Allows Itself to Utilize Two Electron Donors.	Angewandte Chemie - International Edition	2021
33567712	Rebaudioside A Enhances Resistance to Oxidative Stress and Extends Lifespan and Healthspan in .	Antioxidants	2021
33451355	AP2/ERF and R2R3-MYB family transcription factors: potential associations between temperature stress and lipid metabolism in Auxenochlorella protothecoides.	Biotechnology for Biofuels	2021
33450726	Localized increases in CEPT1 and ATGL elevate plasmalogen phosphatidylcholines in HDLs contributing to atheroprotective lipid profiles in hyperglycemic GCK-MODY.	Redox Biology	2021
33876763	Architecture of the mycobacterial succinate dehydrogenase with a membrane-embedded Rieske FeS cluster.	Proc Natl Acad Sci U S A	2021
33876422	NCP2/RHD4/SAC7, SAC6 and SAC8 phosphoinositide phosphatases are required for PtdIns4P and PtdIns(4,5)P2 homeostasis and Arabidopsis development.	New Phytologist	2021
34244497	Prokineticin-2 prevents neuronal cell deaths in a model of traumatic brain injury.	Nat Commun	2021
32797353	Rnf20 deficiency in adipocyte impairs adipose tissue development and thermogenesis.	Protein and Cell	2021
34465437	The role of glutathione-mediated triacylglycerol synthesis in the response to ultra-high cadmium stress in Auxenochlorella protothecoides.	Journal of Environmental Sciences	2021