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Author Details
Full Name
Patrick Lahni
Affiliation
Cincinnati Children's Hospital Medical Center
ORCID
Career Start Year
2007
Papers
59
H Index
23
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
37382480
Comparison of 16 Pediatric Acute Respiratory Distress Syndrome-Associated Plasma Biomarkers With Changing Lung Injury Severity.
Pediatr Crit Care Med
2024
36840516
SEX-DEPENDENT EFFECTS OF ADIPOCYTE STAT3 INHIBITION ON THE INFLAMMATORY RESPONSE DURING SEVERE SEPSIS.
Shock
2023
37802127
Obesity Alters cytokine signaling and gut microbiome in septic mice.
Innate Immun
2023
37079467
PROTECTIVE EFFECTS OF HUMANIN-G IN HEMORRHAGIC SHOCK IN FEMALE MICE VIA AMPKα1-INDEPENDENT MECHANISMS.
Shock
2023
37365661
Detrimental effects of PCSK9 loss-of-function in the pediatric host response to sepsis are mediated through independent influence on Angiopoietin-1.
Crit Care
2023
37092821
Biomarker-Based Risk Stratification in Pediatric Sepsis From a Low-Middle Income Country.
Pediatr Crit Care Med
2023
36513805
Biomarkers estimating baseline mortality risk for neonatal sepsis: nPERSEVERE: neonate-specific sepsis biomarker risk model.
Pediatr Res
2023
36778250
Detrimental effects of PCSK9 loss-of-function in the pediatric host response to sepsis are mediated through independent influence on Angiopoietin-1.
Res Sq
2023
34633847
Population Pharmacokinetic Modeling of Total and Free Ceftriaxone in Critically Ill Children and Young Adults and Monte Carlo Simulations Support Twice Daily Dosing for Target Attainment.
Antimicrob Agents Chemother
2022
35804409
Multi-omic characterization of pediatric ARDS via nasal brushings.
Respir Res
2022
35834274
Choline supplementation attenuates experimental sepsis-associated acute kidney injury.
Am J Physiol Renal Physiol
2022
36119052
Colivelin, a synthetic derivative of humanin, ameliorates endothelial injury and glycocalyx shedding after sepsis in mice.
Front Immunol
2022
35157709
Matrix metalloproteinases and their inhibitors in pediatric severe acute pancreatitis.
PLoS One
2022
33253592
Olfactomedin 4-Positive Neutrophils Are Upregulated after Hemorrhagic Shock.
Am J Respir Cell Mol Biol
2021
33843271
NMR-based serum and urine metabolomic profile reveals suppression of mitochondrial pathways in experimental sepsis-associated acute kidney injury.
Am J Physiol Renal Physiol
2021
34370596
Obesity protects against sepsis-induced and norepinephrine-induced white adipose tissue browning.
Am J Physiol Endocrinol Metab
2021
32117320
Hepatocyte-Specific Deletion of AMPKα1 Results in Worse Outcomes in Mice Subjected to Sepsis in a Sex-Specific Manner.
Front Immunol
2020
30537894
Olfactomedin 4 marks a subset of neutrophils in mice.
Innate Immun
2019
30946605
Reply to Angé et al.
Am J Physiol Heart Circ Physiol
2019
30675002
The Pediatric Sepsis Biomarker Risk Model (PERSEVERE) Biomarkers Predict Clinical Deterioration and Mortality in Immunocompromised Children Evaluated for Infection.
Sci Rep
2019
28915221
Metformin Exerts Beneficial Effects in Hemorrhagic Shock in An AMPKα1-Independent Manner.
Shock
2018
29979626
Age-dependent cardiac function during experimental sepsis: effect of pharmacological activation of AMP-activated protein kinase by AICAR.
Am J Physiol Heart Circ Physiol
2018
30475852
Interleukin-27 as a candidate diagnostic biomarker for bacterial infection in immunocompromised pediatric patients.
PLoS One
2018
28974562
Autophagy and mitochondrial biogenesis impairment contribute to age-dependent liver injury in experimental sepsis: dysregulation of AMP-activated protein kinase pathway.
FASEB J
2018
27635771
Olfactomedin-4 Is a Candidate Marker for a Pathogenic Neutrophil Subset in Septic Shock.
Crit Care Med
2017
28625915
High fat diet-induced obesity increases myocardial injury and alters cardiac STAT3 signaling in mice after polymicrobial sepsis.
Biochim Biophys Acta Mol Basis Dis
2017
28579457
Metformin ameliorates gender-and age-dependent hemodynamic instability and myocardial injury in murine hemorrhagic shock.
Biochim Biophys Acta Mol Basis Dis
2017
27821649
Zinc supplementation leads to immune modulation and improved survival in a juvenile model of murine sepsis.
Innate Immun
2017
27180634
Estimating the probability of bacterial infection using a novel biomarker among pediatric patients in the emergency department.
Biomarkers
2016
26496446
Intestine-Derived Matrix Metalloproteinase-8 Is a Critical Mediator of Polymicrobial Peritonitis.
Crit Care Med
2016
27506554
Matrix Metalloproteinase-8 Augments Bacterial Clearance in a Juvenile Sepsis Model.
Mol Med
2016
27172993
Obesity enhances sepsis-induced liver inflammation and injury in mice.
Obesity (Silver Spring)
2016
27114524
Targeting IL-17A attenuates neonatal sepsis mortality induced by IL-18.
Proc Natl Acad Sci U S A
2016
27435263
Role of matrix metalloproteinase-8 as a mediator of injury in intestinal ischemia and reperfusion.
FASEB J
2016
27513537
Pediatric Sepsis Biomarker Risk Model-II: Redefining the Pediatric Sepsis Biomarker Risk Model With Septic Shock Phenotype.
Crit Care Med
2016
25962083
A Multibiomarker-Based Model for Estimating the Risk of Septic Acute Kidney Injury.
Crit Care Med
2015
26514771
Interleukin-27: a novel biomarker in predicting bacterial infection among the critically ill.
Crit Care
2015
26844289
Prospective Testing and Redesign of a Temporal Biomarker Based Risk Model for Patients With Septic Shock: Implications for Septic Shock Biology.
EBioMedicine
2015
26052715
Postnatal Age Is a Critical Determinant of the Neonatal Host Response to Sepsis.
Mol Med
2015
24430544
Combined zinc supplementation with proinsulin C-peptide treatment decreases the inflammatory response and mortality in murine polymicrobial sepsis.
Shock
2014
31214447
Cerebrospinal fluid levels of extracellular heat shock protein 72: A potential biomarker for bacterial meningitis in children.
J Pediatr Intensive Care
2014
31214445
The extracellular stress response to pediatric cardiopulmonary bypass.
J Pediatr Intensive Care
2014
25386653
Corticosteroids and pediatric septic shock outcomes: a risk stratified analysis.
PLoS One
2014
24848949
Performance of interleukin-27 as a sepsis diagnostic biomarker in critically ill adults.
J Crit Care
2014
24626215
The temporal version of the pediatric sepsis biomarker risk model.
PLoS One
2014
24335447
A multibiomarker-based outcome risk stratification model for adult septic shock*.
Crit Care Med
2014
24489704
Testing the prognostic accuracy of the updated pediatric sepsis biomarker risk model.
PLoS One
2014
23903853
Interleukin 27 as a sepsis diagnostic biomarker in critically ill adults.
Shock
2013
22334256
Short-term high fat feeding increases organ injury and mortality after polymicrobial sepsis.
Obesity (Silver Spring)
2012
23025259
The pediatric sepsis biomarker risk model.
Crit Care
2012
1 - 50 of 59
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row(s) 1 - 30 of 30
Collaborators
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University of Cincinnati College of Medicine
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Akron Children's Hospital
Co-authored papers
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University of Cincinnati College of Medicine
Co-authored papers
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Geoffrey L Allen
Children's Mercy Hospital.
Co-authored papers
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Neal J Thomas
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Jeffrey Nowak
Children's Hospital and Clinics of Minnesota
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Natalie Z Cvijanovich
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10
Michael W Quasney
University of Michigan ann arbor
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9
Christopher J Lindsell
Duke University
Co-authored papers
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Mark W Hall
Nationwide Children's Hospital, The Ohio State University
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Nick Anas
Miami University
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Robert J Freishtat
Center for Genetic Medicine Research, Children's National Research Institute
Co-authored papers
8
John S Giuliano
Yale University School of Medicine
Co-authored papers
8
Paul A Checchia
Texas Children's Hospital and the Baylor College of Medicine
Co-authored papers
8
Keith Meyer
Saint Louis University
Co-authored papers
8
Julie C Fitzgerald
Children's Hospital of Philadelphia
Co-authored papers
7
Scott L Weiss
Sidney Kimmel Medical College at Thomas Jefferson University
Co-authored papers
7
Matthew N Alder
Cincinnati Children's Hospital Medical Center
Co-authored papers
6
Thomas P Shanley
Mott Children's Hospital
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Kimberly W Hart
Vanderbilt University Medical Center
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Sharon Banschbach
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Rainer Gedeit
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