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Author Details

Patrick Lahni
Cincinnati Children's Hospital Medical Center
2007
59
23
PMIDPaper TitleJournal TitlePublished Year
37382480Comparison of 16 Pediatric Acute Respiratory Distress Syndrome-Associated Plasma Biomarkers With Changing Lung Injury Severity.Pediatr Crit Care Med2024
36840516SEX-DEPENDENT EFFECTS OF ADIPOCYTE STAT3 INHIBITION ON THE INFLAMMATORY RESPONSE DURING SEVERE SEPSIS.Shock2023
37802127Obesity Alters cytokine signaling and gut microbiome in septic mice.Innate Immun2023
37079467PROTECTIVE EFFECTS OF HUMANIN-G IN HEMORRHAGIC SHOCK IN FEMALE MICE VIA AMPKα1-INDEPENDENT MECHANISMS.Shock2023
37365661Detrimental effects of PCSK9 loss-of-function in the pediatric host response to sepsis are mediated through independent influence on Angiopoietin-1.Crit Care2023
37092821Biomarker-Based Risk Stratification in Pediatric Sepsis From a Low-Middle Income Country.Pediatr Crit Care Med2023
36513805Biomarkers estimating baseline mortality risk for neonatal sepsis: nPERSEVERE: neonate-specific sepsis biomarker risk model.Pediatr Res2023
36778250Detrimental effects of PCSK9 loss-of-function in the pediatric host response to sepsis are mediated through independent influence on Angiopoietin-1.Res Sq2023
34633847Population Pharmacokinetic Modeling of Total and Free Ceftriaxone in Critically Ill Children and Young Adults and Monte Carlo Simulations Support Twice Daily Dosing for Target Attainment.Antimicrob Agents Chemother2022
35804409Multi-omic characterization of pediatric ARDS via nasal brushings.Respir Res2022
35834274Choline supplementation attenuates experimental sepsis-associated acute kidney injury.Am J Physiol Renal Physiol2022
36119052Colivelin, a synthetic derivative of humanin, ameliorates endothelial injury and glycocalyx shedding after sepsis in mice.Front Immunol2022
35157709Matrix metalloproteinases and their inhibitors in pediatric severe acute pancreatitis.PLoS One2022
33253592Olfactomedin 4-Positive Neutrophils Are Upregulated after Hemorrhagic Shock.Am J Respir Cell Mol Biol2021
33843271NMR-based serum and urine metabolomic profile reveals suppression of mitochondrial pathways in experimental sepsis-associated acute kidney injury.Am J Physiol Renal Physiol2021
34370596Obesity protects against sepsis-induced and norepinephrine-induced white adipose tissue browning.Am J Physiol Endocrinol Metab2021
32117320Hepatocyte-Specific Deletion of AMPKα1 Results in Worse Outcomes in Mice Subjected to Sepsis in a Sex-Specific Manner.Front Immunol2020
30537894Olfactomedin 4 marks a subset of neutrophils in mice.Innate Immun2019
30946605Reply to Angé et al.Am J Physiol Heart Circ Physiol2019
30675002The Pediatric Sepsis Biomarker Risk Model (PERSEVERE) Biomarkers Predict Clinical Deterioration and Mortality in Immunocompromised Children Evaluated for Infection.Sci Rep2019
28915221Metformin Exerts Beneficial Effects in Hemorrhagic Shock in An AMPKα1-Independent Manner.Shock2018
29979626Age-dependent cardiac function during experimental sepsis: effect of pharmacological activation of AMP-activated protein kinase by AICAR.Am J Physiol Heart Circ Physiol2018
30475852Interleukin-27 as a candidate diagnostic biomarker for bacterial infection in immunocompromised pediatric patients.PLoS One2018
28974562Autophagy and mitochondrial biogenesis impairment contribute to age-dependent liver injury in experimental sepsis: dysregulation of AMP-activated protein kinase pathway.FASEB J2018
27635771Olfactomedin-4 Is a Candidate Marker for a Pathogenic Neutrophil Subset in Septic Shock.Crit Care Med2017
28625915High fat diet-induced obesity increases myocardial injury and alters cardiac STAT3 signaling in mice after polymicrobial sepsis.Biochim Biophys Acta Mol Basis Dis2017
28579457Metformin ameliorates gender-and age-dependent hemodynamic instability and myocardial injury in murine hemorrhagic shock.Biochim Biophys Acta Mol Basis Dis2017
27821649Zinc supplementation leads to immune modulation and improved survival in a juvenile model of murine sepsis.Innate Immun2017
27180634Estimating the probability of bacterial infection using a novel biomarker among pediatric patients in the emergency department.Biomarkers2016
26496446Intestine-Derived Matrix Metalloproteinase-8 Is a Critical Mediator of Polymicrobial Peritonitis.Crit Care Med2016
27506554Matrix Metalloproteinase-8 Augments Bacterial Clearance in a Juvenile Sepsis Model.Mol Med2016
27172993Obesity enhances sepsis-induced liver inflammation and injury in mice.Obesity (Silver Spring)2016
27114524Targeting IL-17A attenuates neonatal sepsis mortality induced by IL-18.Proc Natl Acad Sci U S A2016
27435263Role of matrix metalloproteinase-8 as a mediator of injury in intestinal ischemia and reperfusion.FASEB J2016
27513537Pediatric Sepsis Biomarker Risk Model-II: Redefining the Pediatric Sepsis Biomarker Risk Model With Septic Shock Phenotype.Crit Care Med2016
25962083A Multibiomarker-Based Model for Estimating the Risk of Septic Acute Kidney Injury.Crit Care Med2015
26514771Interleukin-27: a novel biomarker in predicting bacterial infection among the critically ill.Crit Care2015
26844289Prospective Testing and Redesign of a Temporal Biomarker Based Risk Model for Patients With Septic Shock: Implications for Septic Shock Biology.EBioMedicine2015
26052715Postnatal Age Is a Critical Determinant of the Neonatal Host Response to Sepsis.Mol Med2015
24430544Combined zinc supplementation with proinsulin C-peptide treatment decreases the inflammatory response and mortality in murine polymicrobial sepsis.Shock2014
31214447Cerebrospinal fluid levels of extracellular heat shock protein 72: A potential biomarker for bacterial meningitis in children.J Pediatr Intensive Care2014
31214445The extracellular stress response to pediatric cardiopulmonary bypass.J Pediatr Intensive Care2014
25386653Corticosteroids and pediatric septic shock outcomes: a risk stratified analysis.PLoS One2014
24848949Performance of interleukin-27 as a sepsis diagnostic biomarker in critically ill adults.J Crit Care2014
24626215The temporal version of the pediatric sepsis biomarker risk model.PLoS One2014
24335447A multibiomarker-based outcome risk stratification model for adult septic shock*.Crit Care Med2014
24489704Testing the prognostic accuracy of the updated pediatric sepsis biomarker risk model.PLoS One2014
23903853Interleukin 27 as a sepsis diagnostic biomarker in critically ill adults.Shock2013
22334256Short-term high fat feeding increases organ injury and mortality after polymicrobial sepsis.Obesity (Silver Spring)2012
23025259The pediatric sepsis biomarker risk model.Crit Care2012
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Collaborators

University of Cincinnati College of Medicine
Co-authored papers 38
Akron Children's Hospital
Co-authored papers 12
University of Cincinnati College of Medicine
Co-authored papers 12
Children's Mercy Hospital.
Co-authored papers 10
Penn State Hershey Children's Hospital
Co-authored papers 10
Children's Hospital and Clinics of Minnesota
Co-authored papers 10
UCSF Benioff Children's Hospital Oakland
Co-authored papers 10
University of Michigan ann arbor
Co-authored papers 9
Duke University
Co-authored papers 9
Nationwide Children's Hospital, The Ohio State University
Co-authored papers 8
Miami University
Co-authored papers 8
Center for Genetic Medicine Research, Children's National Research Institute
Co-authored papers 8
Yale University School of Medicine
Co-authored papers 8
Texas Children's Hospital and the Baylor College of Medicine
Co-authored papers 8
Saint Louis University
Co-authored papers 8
Children's Hospital of Philadelphia
Co-authored papers 7
Sidney Kimmel Medical College at Thomas Jefferson University
Co-authored papers 7
Cincinnati Children's Hospital Medical Center
Co-authored papers 6
Mott Children's Hospital
Co-authored papers 6
Vanderbilt University Medical Center
Co-authored papers 6
Co-authored papers 5
Co-authored papers 5
Medical College of Wisconsin and Children's Wisconsin
Co-authored papers 5
New York-Presbyterian Morgan Stanley Children's Hospital New York NY USA.
Co-authored papers 5
University of Cincinnati College of Medicine
Co-authored papers 4
The Center for Pediatric Pharmacotherapy LLC
Co-authored papers 4
University Hospitals Rainbow Babies and Children's Hospital
Co-authored papers 4
Co-authored papers 4
Children's National Hospital
Co-authored papers 3
Children's Hospital of Philadelphia and University of Pennsylvania
Co-authored papers 3