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Author Details

Mathieu Bourdenx
University College London, UK Dementia Research Institute
2013
44
22
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36683508From Association to Intervention: The Alzheimer's Disease-Associated Processes and Targets (ADAPT) Ontology.J Alzheimers Dis2023
37726343Cortical Lewy body injections induce long-distance pathogenic alterations in the non-human primate brain.NPJ Parkinsons Dis2023
35134347The different autophagy degradation pathways and neurodegeneration.Neuron2022
35363568Protective role of chaperone-mediated autophagy against atherosclerosis.Proc Natl Acad Sci U S A2022
35285474Brain injections of glial cytoplasmic inclusions induce a multiple system atrophy-like pathology.Brain2022
35001895An Argument for Simple Tests of Treatment of Alzheimer's Disease.J Alzheimers Dis2022
35120120Correction: Proteome-wide analysis of chaperone-mediated autophagy targeting motifs.PLoS Biol2022
34110247Chaperone-mediated autophagy: a gatekeeper of neuronal proteostasis.Autophagy2021
33854069Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice.Nat Commun2021
33891876Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome.Cell2021
34876687Reciprocal regulation of chaperone-mediated autophagy and the circadian clock.Nat Cell Biol2021
32426502Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in nonhuman primates.Sci Adv2020
32902378CB<sub>1</sub>-receptor-mediated inhibitory LTD triggers presynaptic remodeling via protein synthesis and ubiquitination.Elife2020
32380543Bidirectional gut-to-brain and brain-to-gut propagation of synucleinopathy in non-human primates.Brain2020
30382371Rare variants in the neuronal ceroid lipofuscinosis gene MFSD8 are candidate risk factors for frontotemporal dementia.Acta Neuropathol2019
31434803Transcription factor EB overexpression prevents neurodegeneration in experimental synucleinopathies.JCI Insight2019
31150375Proteome-wide analysis of chaperone-mediated autophagy targeting motifs.PLoS Biol2019
30064266Systemic Gene Delivery by Single-Dose Intracardiac Administration of scAAV2/9 and scAAV2/rh10 Variants in Newborn Rats.Hum Gene Ther Methods2018
30129476Selective autophagy as a potential therapeutic target for neurodegenerative disorders.Lancet Neurol2018
26209472Protein aggregation and neurodegeneration in prototypical neurodegenerative diseases: Examples of amyloidopathies, tauopathies and synucleinopathies.Prog Neurobiol2017
28197068Exosomes, an Unmasked Culprit in Neurodegenerative Diseases.Front Neurosci2017
28411117In vitro α-synuclein neurotoxicity and spreading among neurons and astrocytes using Lewy body extracts from Parkinson disease brains.Neurobiol Dis2017
28374864Lack of spontaneous age-related brain pathology in Octodon degus: a reappraisal of the model.Sci Rep2017
28367813[Autophagy and brain: the case of neurodegenerative diseases].Med Sci (Paris)2017
28539659Involvement of the bed nucleus of the stria terminalis in L-Dopa induced dyskinesia.Sci Rep2017
28853717In utero delivery of rAAV2/9 induces neuronal expression of the transgene in the brain: towards new models of Parkinson's disease.Gene Ther2017
25146322Selective Inactivation of Striatal FosB/οFosB-Expressing Neurons Alleviates L-DOPA-Induced Dyskinesia.Biol Psychiatry2016
26584009Early prenatal exposure to MPTP does not affect nigrostrial neurons in macaque monkey.Synapse2016
26926119Targeting α-synuclein: Therapeutic options.Mov Disord2016
26761717Nanoparticles restore lysosomal acidification defects: Implications for Parkinson and other lysosomal-related diseases.Autophagy2016
26947123What lysosomes actually tell us about Parkinson's disease?Ageing Res Rev2016
25766677D1 dopamine receptor stimulation impairs striatal proteasome activity in Parkinsonism through 26S proteasome disassembly.Neurobiol Dis2015
29901880Experimental modelling of -synuclein aggregation and spreading in synucleinopathies.Bull Acad Natl Med2015
26209473Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson's disease.Prog Neurobiol2015
26050140Targeting α-synuclein for treatment of Parkinson's disease: mechanistic and therapeutic considerations.Lancet Neurol2015
26205255Lack of additive role of ageing in nigrostriatal neurodegeneration triggered by α-synuclein overexpression.Acta Neuropathol Commun2015
24148855Abnormal structure-specific peptide transmission and processing in a primate model of Parkinson's disease and l-DOPA-induced dyskinesia.Neurobiol Dis2014
25214445Down-regulating α-synuclein for treating synucleopathies.Mov Disord2014
25177278Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death.Front Neuroanat2014
24917785Systemic gene delivery to the central nervous system using Adeno-associated virus.Front Mol Neurosci2014
23568844Phosphorylation of α-synuclein at Ser120 accelerates neurodegeneration.Mov Disord2013
23436630Alpha-synuclein inoculation initiates a neurodegenerative cascade in nontransgenic mice.Mov Disord2013
23712582Allograft of stem cell-derived dopaminergic neurons for Parkinson's disease.Mov Disord2013
23677895DNA as the next digital information storage support.Mov Disord2013
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