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Author Details
Full Name
Stanley B Prusiner
Affiliation
Weill Institute for Neurosciences, University of California San Francisco
ORCID
Career Start Year
1965
Papers
585
H Index
152
Expertise
CM4AI Collaborator
Andrej Sali (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36399277
Aβ and Tau Prions Causing Alzheimer's Disease.
Methods Mol Biol
2023
37236970
Stacked binding of a PET ligand to Alzheimer's tau paired helical filaments.
Nat Commun
2023
35115402
Different α-synuclein prion strains cause dementia with Lewy bodies and multiple system atrophy.
Proc Natl Acad Sci U S A
2022
36276634
Trans-channel fluorescence learning improves high-content screening for Alzheimer's disease therapeutics.
Nat Mach Intell
2022
36018376
Multiple system atrophy prions transmit neurological disease to mice expressing wild-type human α-synuclein.
Acta Neuropathol
2022
36343257
Aβ and tau prions feature in the neuropathogenesis of Down syndrome.
Proc Natl Acad Sci U S A
2022
34064393
How an Infection of Sheep Revealed Prion Mechanisms in Alzheimer's Disease and Other Neurodegenerative Disorders.
Int J Mol Sci
2021
33848474
Tau aggregates are RNA-protein assemblies that mislocalize multiple nuclear speckle components.
Neuron
2021
33869960
Silver Benzoate Facilitates the Copper-Catalyzed C-N Coupling of Iodoazoles with Aromatic Nitrogen Heterocycles.
ACS Omega
2021
33929208
Water-Soluble Iridium Photoredox Catalyst for the Trifluoromethylation of Biomolecule Substrates in Phosphate Buffered Saline Solvent.
Org Lett
2021
32123368
Prion protein - mediator of toxicity in multiple proteinopathies.
Nat Rev Neurol
2020
32017806
Kinetics of α-synuclein prions preceding neuropathological inclusions in multiple system atrophy.
PLoS Pathog
2020
32071678
Discovery of 4-Piperazine Isoquinoline Derivatives as Potent and Brain-Permeable Tau Prion Inhibitors with CDK8 Activity.
ACS Med Chem Lett
2020
32803268
Expanding spectrum of prion diseases.
Emerg Top Life Sci
2020
32949533
Prion biology: implications for Alzheimer's disease therapeutics.
Lancet Neurol
2020
30690664
Multiple system atrophy prions retain strain specificity after serial propagation in two different Tg(SNCA*A53T) mouse lines.
Acta Neuropathol
2019
31109379
Replication of multiple system atrophy prions in primary astrocyte cultures from transgenic mice expressing human α-synuclein.
Acta Neuropathol Commun
2019
28849371
MSA prions exhibit remarkable stability and resistance to inactivation.
Acta Neuropathol
2018
29950625
Citations must default to the online publication date.
Nature
2018
28193770
β-Amyloid Prions and the Pathobiology of Alzheimer's Disease.
Cold Spring Harb Perspect Med
2018
28213437
α-Synuclein: Multiple System Atrophy Prions.
Cold Spring Harb Perspect Med
2018
29311311
Structural heterogeneity and intersubject variability of Aβ in familial and sporadic Alzheimer's disease.
Proc Natl Acad Sci U S A
2018
29279394
Familial Parkinson's point mutation abolishes multiple system atrophy prion replication.
Proc Natl Acad Sci U S A
2018
29319162
A long-lived Aβ oligomer resistant to fibrillization.
Biopolymers
2018
28837163
A 31-residue peptide induces aggregation of tau's microtubule-binding region in cells.
Nat Chem
2017
28246183
Bioassays and Inactivation of Prions.
Cold Spring Harb Perspect Biol
2017
28096244
Experimental Models of Inherited PrP Prion Diseases.
Cold Spring Harb Perspect Med
2017
28096242
Developing Therapeutics for PrP Prion Diseases.
Cold Spring Harb Perspect Med
2017
29157304
A novel vector for transgenesis in the rat CNS.
Acta Neuropathol Commun
2017
29059326
Kinetics of Human Mutant Tau Prion Formation in the Brains of 2 Transgenic Mouse Lines.
JAMA Neurol
2017
29203673
Evidence for sortilin modulating regional accumulation of human tau prions in transgenic mice.
Proc Natl Acad Sci U S A
2017
27402759
FoxO3 regulates neuronal reprogramming of cells from postnatal and aging mice.
Proc Natl Acad Sci U S A
2016
27911827
Tau prions from Alzheimer's disease and chronic traumatic encephalopathy patients propagate in cultured cells.
Proc Natl Acad Sci U S A
2016
27414264
Structural Polymorphism of Alzheimer's β-Amyloid Fibrils as Controlled by an E22 Switch: A Solid-State NMR Study.
J Am Chem Soc
2016
27350609
Towards authentic transgenic mouse models of heritable PrP prion diseases.
Acta Neuropathol
2016
27440899
Guinea Pig Prion Protein Supports Rapid Propagation of Bovine Spongiform Encephalopathy and Variant Creutzfeldt-Jakob Disease Prions.
J Virol
2016
27317802
Optimization of Aryl Amides that Extend Survival in Prion-Infected Mice.
J Pharmacol Exp Ther
2016
25809267
Structural studies of truncated forms of the prion protein PrP.
Biophys J
2015
26324905
Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism.
Proc Natl Acad Sci U S A
2015
26287631
Prion Protein-Antibody Complexes Characterized by Chromatography-Coupled Small-Angle X-Ray Scattering.
Biophys J
2015
26286986
Propagation of prions causing synucleinopathies in cultured cells.
Proc Natl Acad Sci U S A
2015
26094969
Modulation of Creutzfeldt-Jakob disease prion propagation by the A224V mutation.
Ann Neurol
2015
26224882
Different 2-Aminothiazole Therapeutics Produce Distinct Patterns of Scrapie Prion Neuropathology in Mouse Brains.
J Pharmacol Exp Ther
2015
26116725
Use of a 2-aminothiazole to Treat Chronic Wasting Disease in Transgenic Mice.
J Infect Dis
2015
25695325
Mechanism of scrapie prion precipitation with phosphotungstate anions.
ACS Chem Biol
2015
24699458
Evidence that bank vole PrP is a universal acceptor for prions.
PLoS Pathog
2014
24982139
Serial propagation of distinct strains of Aβ prions from Alzheimer's disease patients.
Proc Natl Acad Sci U S A
2014
24982137
Distinct synthetic Aβ prion strains producing different amyloid deposits in bigenic mice.
Proc Natl Acad Sci U S A
2014
24860095
Mouse models for studying the formation and propagation of prions.
J Biol Chem
2014
24530226
Novel compounds lowering the cellular isoform of the human prion protein in cultured human cells.
Bioorg Med Chem
2014
1 - 50 of 585
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