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Author Details

Zhihua Qiu
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
1992
47
20
Timothy Clark (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36656412Vaccine Targeting Alpha 1D-Adrenergic Receptor Improved Metabolic Syndrome in Mice.Cardiovasc Drugs Ther2024
36562301Peptide Vaccine Against ADAMTS-7 Ameliorates Atherosclerosis and Postinjury Neointima Hyperplasia.Circulation2023
37664844G protein-coupled estrogen receptor: a promising therapeutic target for aldosterone-induced hypertension.Front Endocrinol (Lausanne)2023
37304948Roles and mechanism of IL-11 in vascular diseases.Front Cardiovasc Med2023
36997634A novel vaccine targeting β1-adrenergic receptor.Hypertens Res2023
32725442PCSK9Qβ-003 Vaccine Attenuates Atherosclerosis in Apolipoprotein E-Deficient Mice.Cardiovasc Drugs Ther2021
33516876Anti-ATR001 monoclonal antibody ameliorates atherosclerosis through beta-arrestin2 pathway.Biochem Biophys Res Commun2021
34977175Inhibition of Sphingosine-1-Phosphate Receptor 2 Prevents Thoracic Aortic Dissection and Rupture.Front Cardiovasc Med2021
34938778Case Report: Cardiac Toxicity Associated With Immune Checkpoint Inhibitors.Front Cardiovasc Med2021
34703652Inhibition of microRNA-30a alleviates vascular remodeling in pulmonary arterial hypertension.Mol Ther Nucleic Acids2021
34222378Long-Term Effect of a Vaccine Targeting Endothelin-1 Receptor Type A in Pulmonary Arterial Hypertension.Front Cardiovasc Med2021
33155736Immunotherapy against angiotensin II receptor ameliorated insulin resistance in a leptin receptor-dependent manner.FASEB J2021
31625597A bivalent antihypertensive vaccine targeting L-type calcium channels and angiotensin AT<sub>1</sub> receptors.Br J Pharmacol2020
31870234Vaccine Against PCSK9 Improved Renal Fibrosis by Regulating Fatty Acid β-Oxidation.J Am Heart Assoc2020
30587854The ATRQβ-001 vaccine improves cardiac function and prevents postinfarction cardiac remodeling in mice.Hypertens Res2019
31607175Vaccine Targeted Alpha 1D-Adrenergic Receptor for Hypertension.Hypertension2019
31512549ATRQβ-001 Vaccine Prevents Experimental Abdominal Aortic Aneurysms.J Am Heart Assoc2019
31118151Immunotherapy of Endothelin-1 Receptor Type A for Pulmonary Arterial Hypertension.J Am Coll Cardiol2019
28798362A large family with inherited optic disc anomalies: a correlation between a new genetic locus and complex ocular phenotypes.Sci Rep2017
28974760Immune Response of A Novel ATR-AP205-001 Conjugate Anti-hypertensive Vaccine.Sci Rep2017
28970592A Therapeutic Peptide Vaccine Against PCSK9.Sci Rep2017
26771341ATRQβ-001 vaccine prevents atherosclerosis in apolipoprotein E-null mice.J Hypertens2016
26407577Vaccination against type 1 angiotensin receptor prevents streptozotocin-induced diabetic nephropathy.J Mol Med (Berl)2016
24609215Angiotensin II receptor type 1 autoantibodies promote endothelial microparticles formation through activating p38 MAPK pathway.J Hypertens2014
23184378Effectiveness and safety of a therapeutic vaccine against angiotensin II receptor type 1 in hypertensive animals.Hypertension2013
23825541Therapeutic vaccines against human and rat renin in spontaneously hypertensive rats.PLoS One2013
22131354Functional analysis of a novel antagonistic antibody against the short epitope of the α1A-adrenergic receptor.Cardiovasc Res2012
17409194Histones associated with downregulated genes are hypo-acetylated in Huntington's disease models.Hum Mol Genet2007
16595660Sp1 is up-regulated in cellular and transgenic models of Huntington disease, and its reduction is neuroprotective.J Biol Chem2006
15169786Apolipoprotein E receptors mediate neurite outgrowth through activation of p44/42 mitogen-activated protein kinase in primary neurons.J Biol Chem2004
12799020Interleukin-6, beta-amyloid peptide and NMDA interactions in rat cortical neurons.J Neuroimmunol2003
14614897ApoE isoforms affect neuronal N-methyl-D-aspartate calcium responses and toxicity via receptor-mediated processes.Neuroscience2003
11839752alpha 2-Macroglobulin exposure reduces calcium responses to N-methyl-D-aspartate via low density lipoprotein receptor-related protein in cultured hippocampal neurons.J Biol Chem2002
11421596A novel approach for studying endogenous abeta processing using cultured primary neurons isolated from APP transgenic mice.Exp Neurol2001
11379818Elevation of LDL receptor-related protein levels via ligand interactions in Alzheimer disease and in vitro.J Neuropathol Exp Neurol2001
10501182Alpha2-macroglobulin enhances the clearance of endogenous soluble beta-amyloid peptide via low-density lipoprotein receptor-related protein in cortical neurons.J Neurochem1999
9852582Chronic interleukin-6 alters NMDA receptor-mediated membrane responses and enhances neurotoxicity in developing CNS neurons.J Neurosci1998
9630481Neonatal alcohol exposure reduces NMDA induced Ca2+ signaling in developing cerebellar granule neurons.Brain Res1998
9666276Cannabinoids alter neurotoxicity produced by interleukin-6 in central nervous system neurons.Adv Exp Med Biol1998
8779845Cholinergic stimulation modulates negative inotropic effect of cocaine on ferret ventricular myocardium.Am J Physiol1996
8896447Tyrosine kinase activation is an immediate and essential step in hypotonic cell swelling-induced ERK activation and c-fos gene expression in cardiac myocytes.EMBO J1996
8787651Cannabinoids and interleukin-6 enhance the response to NMDA in developing CNS neurons.Adv Exp Med Biol1996
7472429Interleukin-6 selectively enhances the intracellular calcium response to NMDA in developing CNS neurons.J Neurosci1995
8001266Angiotensin II and other hypertrophic stimuli mediated by G protein-coupled receptors activate tyrosine kinase, mitogen-activated protein kinase, and 90-kD S6 kinase in cardiac myocytes. The critical role of Ca(2+)-dependent signaling.Circ Res1995
8092296Ca2+ handling and myofibrillar Ca2+ sensitivity in ferret cardiac myocytes with pressure-overload hypertrophy.Am J Physiol1994
8358533Differential effects of cocaine and cocaethylene on intracellular Ca2+ and myocardial contraction in cardiac myocytes.Br J Pharmacol1993
1516644Effects of endothelin on intracellular Ca2+ and contractility in single ventricular myocytes from the ferret and human.Eur J Pharmacol1992
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Collaborators

James P Morgan
Co-authored papers 6
Bradley T Hyman
Massachusetts General Hospital
Co-authored papers 5
Steven M Hersch
Inc. University Avenue
Co-authored papers 2
Seigo Izumo
Beth Israel Deaconess Medical Center.
Co-authored papers 2
Jang-Ho J Cha
Novartis Institutes for Biomedical Research
Co-authored papers 2
Feng Zhu
Basic Medical College, Qingdao University
Co-authored papers 2
Caroline L Benn
Pfizer Neuroscience and Pain Research Unit, Pfizer Ltd.
Co-authored papers 2
Eva Xia
Mass General Institute for Neurodegenerative Disease, Massachusetts General Hospital
Co-authored papers 1
Chuan-Ju Liu
Co-authored papers 1
B??reng??re Bouzou
Co-authored papers 1
Miao Yu
Co-authored papers 1
Weiyi Xia
Eye & ENT Hospital, Shanghai Medical School, Fudan University
Co-authored papers 1
Derek P DiRocco
Brigham and Women's Hospital, Harvard Medical School
Co-authored papers 1
Mee-Ohk Kim
University of California san francisco
Co-authored papers 1
Kelly E Glajch
Neurodegenerative Diseases Research Unit
Co-authored papers 1
Qingbo Xu
Co-authored papers 1
Timothy Clark (CM4AI)
University of Virginia
Co-authored papers 1
George J Yohrling
CHDI Management/CHDI Foundation
Co-authored papers 1
Ghazaleh Sadri-Vakili
Sean M. Healey & AMG Center for ALS at Mass General
Co-authored papers 1
Ryan P Overland
Co-authored papers 1
Prianka Chawla
Center for Regenerative Therapies Dresden, Technische Universitat Dresden
Co-authored papers 1
Tim Clark
Co-authored papers 1
Release 1.2