Author details

Full Name

Sundeep Khosla

Affiliation

ORCID

Career Start Year

1980

Papers

501

H Index

108

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
38051584	Senotherapeutic drug treatment ameliorates chemotherapy-induced cachexia.	JCI Insight	2024
37524694	Multiparametric senescent cell phenotyping reveals targets of senolytic therapy in the aged murine skeleton.		2023
36395774	Osteoporosis in the USA: prevention and unmet needs.	Lancet Diabetes Endocrinol	2023
37821702	Apoptotic stress causes mtDNA release during senescence and drives the SASP.	Nature	2023
37808401	Single-Cell Integration of BMD GWAS Results Prioritize Candidate Genes Influencing Age-Related Bone Loss.		2023
37808391	Modest Effects of Osteoclast-Specific ERÎ± Deletion after Skeletal Maturity.		2023
37732678	Opportunistic Screening With CT: Comparison of Phantomless BMD Calibration Methods.		2023
37576432	Evidence in Humans for Bone as an Endocrine Organ Regulating Energy Metabolism.		2023
37566158	Previous fracture and subsequent fracture risk: a meta-analysis to update FRAX.	Osteoporos Int	2023
37961856	Calorie restriction reduces biomarkers of cellular senescence in humans.		2023
37688671	Influences of Aged Bone Marrow Macrophages on Skeletal Health and Senescence.		2023
37283656	-- Decreases with Age in Mice and Humans and Inhibits Osteoblast Senescence.		2023
37154858	In vitro and in vivo effects of zoledronic acid on senescence and senescence-associated secretory phenotype markers.	Aging (Albany NY)	2023
37399469	Validating the Fracture Risk Assessment Tool Score in a US Population-Based Study of Patients With Rheumatoid Arthritis.	J Rheumatol	2023
36711531	Multiparametric senescent cell phenotyping reveals CD24 osteolineage cells as targets of senolytic therapy in the aged murine skeleton.		2023
37132542	A Fracture Risk Assessment Tool for High Resolution Peripheral Quantitative Computed Tomography.	J Bone Miner Res	2023
37325957	Drugs Targeting Mechanisms of Aging to Delay Age-Related Disease and Promote Healthspan: Proceedings of a National Institute on Aging Workshop.		2023
36809340	Local senolysis in aged mice only partially replicates the benefits of systemic senolysis.	J Clin Invest	2023
37380899	Mapping cellular senescence networks in human diabetic foot ulcers.		2023
37118118	Senescent cells, senolytics and tissue repair: the devil may be in the dosing.		2023
36865244	<i>In vitro</i> and <i>in vivo</i> effects of zoledronate on senescence and senescence-associated secretory phenotype markers.	bioRxiv	2023
37304840	ST-V-Net: incorporating shape prior into convolutional neural networks for proximal femur segmentation.	Complex Intell Systems	2023
36729139	Reference Intervals for Bone Impact Microindentation in Healthy Adults: A Multi-Centre International Study.		2023
35104801	Cellular senescence and the skeleton: pathophysiology and therapeutic implications.	Journal of Clinical Investigation	2022
35974106	A new gene set identifies senescent cells and predicts senescence-associated pathways across tissues.	Nat Commun	2022
35700807	Identification of a suitable endogenous control miRNA in bone aging and senescence.	Gene	2022
35947145	Guanylyl Cyclase-B Dependent Bone Formation in Mice is Associated with Youth, Increased Osteoblasts, and Decreased Osteoclasts.	Calcified Tissue International	2022
36342703	Daily Low-Dose Aspirin and Risk of Serious Falls and Fractures in Healthy Older People: A Substudy of the ASPREE Randomized Clinical Trial.	JAMA Intern Med	2022
35749726	Effects of diabetes on osteocytes.	Current Opinion in Endocrinology, Diabetes and Obesity	2022
36147777	Characterization of cellular senescence in aging skeletal muscle.	Nature Aging	2022
35363946	Targeted clearance of p21- but not p16-positive senescent cells prevents radiation-induced osteoporosis and increased marrow adiposity.	Aging Cell	2022
35789113	Skeletal Effects of Inducible ERÎ± Deletion in Osteocytes in Adult Mice.	Journal of Bone and Mineral Research	2022
35545088	The crosstalk between bone remodeling and energy metabolism: A translational perspective.		2022
35292270	Orally-active, clinically-translatable senolytics restore Î±-Klotho in mice and humans.	eBioMedicine	2022
35247283	Bone Marrow Adiposity in Models of Radiation- and Aging-Related Bone Loss Is Dependent on Cellular Senescence.	Journal of Bone and Mineral Research	2022
35182420	Fracture Healing in the Setting of Endocrine Diseases, Aging, and Cellular Senescence.	Endocrine Reviews	2022
34953074	Bone Microarchitecture Phenotypes Identified in Older Adults Are Associated With Different Levels of Osteoporotic Fracture Risk.	J Bone Miner Res	2022
34490915	Validation of the Surrogate Threshold Effect for Change in Bone Mineral Density as a Surrogate Endpoint for Fracture Outcomes: The FNIH-ASBMR SABRE Project.	J Bone Miner Res	2022
34375437	Fisetin for COVID-19 in skilled nursing facilities: Senolytic trials in the COVID era.	J Am Geriatr Soc	2021
34122326	Global and Spatial Compartmental Interrelationships of Bone Density, Microstructure, Geometry and Biomechanics in the Distal Radius in a Colles' Fracture Study Using HR-pQCT.	Frontiers in Endocrinology	2021
34047849	Opportunistic application of phantom-less calibration methods for fracture risk prediction using QCT/FEA.	European Radiology	2021
34103349	Senolytics reduce coronavirus-related mortality in old mice.	Science	2021
33606665	Risk of bone fractures after the diagnosis of adrenal adenomas: a population-based cohort study.	Eur J Endocrinol	2021
33764576	Neutrophils induce paracrine telomere dysfunction and senescence in ROS-dependent manner.	EMBO Journal	2021
32916023	Treatment-Related Changes in Bone Turnover and Fracture Risk Reduction in Clinical Trials of Antiresorptive Drugs: Proportion of Treatment Effect Explained.	J Bone Miner Res	2021
33341947	Senescent cells exacerbate chronic inflammation and contribute to periodontal disease progression in old mice.	Journal of Periodontology	2021
33227126	Pathophysiologic importance of visceral adipose tissue in women with heart failure and preserved ejection fraction.	European Heart Journal	2021
32997601	Senolytic Drugs: Reducing Senescent Cell Viability to Extend Health Span.	Annu Rev Pharmacol Toxicol	2021
34518671	Update on the pathogenesis and treatment of skeletal fragility in type 2 diabetes mellitus.	Nature Reviews Endocrinology	2021
34617510	Modulation of fracture healing by the transient accumulation of senescent cells.	eLife	2021