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Author Details

Limei Hu
Aier Eye Hospital of Wuhan University
2001
54
32
PMIDPaper TitleJournal TitlePublished Year
37012887Single-Cell RNA sequencing highlights the regulatory role of T cell marker genes Ctla4, Ccl5 and Tcf7 in corneal allograft rejection of mouse model.Int Immunopharmacol2023
35262820Pyrimethamine inhibits cell growth by inducing cell senescence and boosting CD8<sup>+</sup> T-cell mediated cytotoxicity in colorectal cancer.Mol Biol Rep2022
36047191Evacetrapib Elicits Antitumor Effects on Colorectal Cancer by Inhibiting the Wnt/β-Catenin Signaling Pathway and Activating the JNK Signaling Pathway.Biol Pharm Bull2022
33545202Ligustilide inhibits the proliferation of human osteoblastoma MG63 cells through the TLR4-ERK pathway.Life Sci2022
33309987Altered Regulation of HIF-1α in Naive- and Drug-Resistant EGFR-Mutant NSCLC: Implications for a Vascular Endothelial Growth Factor-Dependent Phenotype.J Thorac Oncol2021
32109374Proteome Instability Is a Therapeutic Vulnerability in Mismatch Repair-Deficient Cancer.Cancer Cell2020
32878980A YAP/FOXM1 axis mediates EMT-associated EGFR inhibitor resistance and increased expression of spindle assembly checkpoint components.Sci Transl Med2020
27741356MIIP haploinsufficiency induces chromosomal instability and promotes tumour progression in colorectal cancer.J Pathol2017
28121485MIR506 induces autophagy-related cell death in pancreatic cancer cells by targeting the STAT3 pathway.Autophagy2017
28985752Erratum to: MIIP remodels Rac1-mediated cytoskeleton structure in suppression of endometrial cancer metastasis.J Hematol Oncol2017
28981122Base-resolution stratification of cancer mutations using functional variomics.Nat Protoc2017
29045845Revealing the Determinants of Widespread Alternative Splicing Perturbation in Cancer.Cell Rep2017
25893308IGFBP2 potentiates nuclear EGFR-STAT3 signaling.Oncogene2016
29179445ADAMTS16 mutations sensitize ovarian cancer cells to platinum-based chemotherapy.Oncotarget2016
27760566MIIP remodels Rac1-mediated cytoskeleton structure in suppression of endometrial cancer metastasis.J Hematol Oncol2016
27659045IGFBP2 Activates the NF-κB Pathway to Drive Epithelial-Mesenchymal Transition and Invasive Character in Pancreatic Ductal Adenocarcinoma.Cancer Res2016
25230372MiR-506 inhibits multiple targets in the epithelial-to-mesenchymal transition network and is associated with good prognosis in epithelial ovarian cancer.J Pathol2015
26181259Association of Somatic Mutations of ADAMTS Genes With Chemotherapy Sensitivity and Survival in High-Grade Serous Ovarian Carcinoma.JAMA Oncol2015
25995442Augmentation of response to chemotherapy by microRNA-506 through regulation of RAD51 in serous ovarian cancers.J Natl Cancer Inst2015
25737557Genomically amplified Akt3 activates DNA repair pathway and promotes glioma progression.Proc Natl Acad Sci U S A2015
24677166MiR-101 suppresses the epithelial-to-mesenchymal transition by targeting ZEB1 and ZEB2 in ovarian carcinoma.Oncol Rep2014
24598126Post-transcriptional regulatory network of epithelial-to-mesenchymal and mesenchymal-to-epithelial transitions.J Hematol Oncol2014
23298836The tumorigenic FGFR3-TACC3 gene fusion escapes miR-99a regulation in glioblastoma.J Clin Invest2013
23410973Integrated analyses identify a master microRNA regulatory network for the mesenchymal subtype in serous ovarian cancer.Cancer Cell2013
22345562Insulin-like growth factor-binding protein 2-driven glioma progression is prevented by blocking a clinically significant integrin, integrin-linked kinase, and NF-κB network.Proc Natl Acad Sci U S A2012
22245216Integrative molecular profiling reveals asparagine synthetase is a target in castration-resistant prostate cancer.Am J Pathol2012
22363599Mitosis phase enrichment with identification of mitotic centromere-associated kinesin as a therapeutic target in castration-resistant prostate cancer.PLoS One2012
21622717NGAL expression is elevated in both colorectal adenoma-carcinoma sequence and cancer progression and enhances tumorigenesis in xenograft mouse models.Clin Cancer Res2011
21810988Functional SNP in the microRNA-367 binding site in the 3'UTR of the calcium channel ryanodine receptor gene 3 (RYR3) affects breast cancer risk and calcification.Proc Natl Acad Sci U S A2011
19896763Deletion of the WWOX gene and frequent loss of its protein expression in human osteosarcoma.Cancer Lett2010
20218740Genomic characterization of gene copy-number aberrations in endometrial carcinoma cell lines derived from endometrioid-type endometrial adenocarcinoma.Technol Cancer Res Treat2010
20218738APEX1 gene amplification and its protein overexpression in osteosarcoma: correlation with recurrence, metastasis, and survival.Technol Cancer Res Treat2010
19308044NGAL decreases E-cadherin-mediated cell-cell adhesion and increases cell motility and invasion through Rac1 in colon carcinoma cells.Lab Invest2009
19887608Inhibition of lipocalin 2 impairs breast tumorigenesis and metastasis.Cancer Res2009
19341485The subcellular localization of IGFBP5 affects its cell growth and migration functions in breast cancer.BMC Cancer2009
19222862Using cell fate attractors to uncover transcriptional regulation of HL60 neutrophil differentiation.BMC Syst Biol2009
18710598Multifunctional roles of insulin-like growth factor binding protein 5 in breast cancer.Breast Cancer Res2008
18662989Critical and distinct roles of p16 and telomerase in regulating the proliferative life span of normal human prostate epithelial progenitor cells.J Biol Chem2008
17921698Activation of polyamine catabolism by N1, N11-diethylnorspermine alters the cellular localization of mTOR and downregulates mTOR protein level in glioblastoma cells.Cancer Biol Ther2007
16569642An interaction between insulin-like growth factor-binding protein 2 (IGFBP2) and integrin alpha5 is essential for IGFBP2-induced cell mobility.J Biol Chem2006
16986125Early effects of imatinib mesylate on the expression of insulin-like growth factor binding protein-3 and positron emission tomography in patients with gastrointestinal stromal tumor.Cancer2006
17158952Mitochondrial respiration defects in cancer cells cause activation of Akt survival pathway through a redox-mediated mechanism.J Cell Biol2006
15778693Alterations in transcription clusters underlie development of bladder cancer along papillary and nonpapillary pathways.Lab Invest2005
15138604Distinguishing key biological pathways between primary breast cancers and their lymph node metastases by gene function-based clustering analysis.Int J Oncol2004
17272032Quantification of in vitro cell invasion through image analysis.Conf Proc IEEE Eng Med Biol Soc2004
15196312Improving signal intensities for genes with low-expression on oligonucleotide microarrays.BMC Genomics2004
15022276Differential gene and protein expression in primary breast malignancies and their lymph node metastases as revealed by combined cDNA microarray and tissue microarray analysis.Cancer2004
12613262RNA amplification strategies for cDNA microarray experiments.Biotechniques2003
12907597Insulin-like growth factor binding protein 2 enhances glioblastoma invasion by activating invasion-enhancing genes.Cancer Res2003
14614330Apoptotic response to 5-fluorouracil treatment is mediated by reduced polyamines, non-autocrine Fas ligand and induced tumor necrosis factor receptor 2.Cancer Biol Ther2003
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Collaborators

Wei Zhang
The University of Texas MD Anderson Cancer Center
Co-authored papers 29
David Cogdell
The University of Texas MD Anderson Cancer Center
Co-authored papers 20
Ilya Shmulevich
Institute for Systems Biology
Co-authored papers 11
Anil K Sood
The University of Texas MD Anderson Cancer Center
Co-authored papers 10
Gregory N Fuller
MD Anderson Cancer Center
Co-authored papers 9
Yuexin Liu
The University of Texas MD Anderson Cancer Center
Co-authored papers 9
Wei Zhang
Children's Hospital, Zhejiang University School of Medicine
Co-authored papers 9
Da Yang
Co-authored papers 8
Matti Nykter
Prostate Cancer Research Center, Tampere University and Tays Cancer Center
Co-authored papers 5
Yingmei Wang
Tianjin Medical University General Hospital
Co-authored papers 4
Rajesha Rupaimoole
Harvard Medical School, Beth Israel Deaconess Medical Center
Co-authored papers 3
Kevin R Coombes
Medical College of Georgia
Co-authored papers 3
Matti Annala
University of British Columbia
Co-authored papers 3
Jonathan C Trent
Sylvester Comprehensive Cancer Center, University of Miami
Co-authored papers 3
Nidhi Sahni
The University of Texas MD Anderson Cancer Center
Co-authored papers 3
Gordon B Mills
Knight Cancer Institute, Oregon Health and Sciences University
Co-authored papers 2
Fei Teng
Ningbo First Hospital
Co-authored papers 2
Jianhua Hu
Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences
Co-authored papers 2
Lixia Diao
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
Daniel J McGrail
Center for Immunotherapy and Precision Immuno-Oncology, Cleveland Clinic
Co-authored papers 2
Jilong Yang
Tianjin Medical University Cancer Institute and Hospital
Co-authored papers 2
Scott Kopetz
University of Texas MD Anderson Cancer Center
Co-authored papers 2
Eleni Efstathiou
Houston Methodist Cancer Center
Co-authored papers 2
Keith A Baggerly
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
William F Symmans
Co-authored papers 2
Chad V Pecot
University of North Carolina at Chapel Hill
Co-authored papers 2
Nora M Navone
MD Anderson Cancer Center
Co-authored papers 2
Shiaw-Yih Lin
The University of Texas MD Anderson Cancer Center
Co-authored papers 2
Song Yi
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Release 1.2