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Author Details

Carole L Yauk
University of Ottawa
1996
226
45
PMIDPaper TitleJournal TitlePublished Year
36534918In vitro transcriptomic analyses reveal pathway perturbations, estrogenic activities, and potencies of data-poor BPA alternative chemicals.Toxicol Sci2023
37941476Toxicological Mechanisms and Potencies of Organophosphate Esters in KGN Human Ovarian Granulosa Cells as Revealed by High-throughput Transcriptomics.Toxicol Sci2023
37889188Report of the 3rd and 4th Mystery of Reactive Oxygen Species Conference.ALTEX2023
38058303The functional mutational landscape of the <i>lacZ</i> gene.iScience2023
37341741Duplex sequencing provides detailed characterization of mutation frequencies and spectra in the bone marrow of MutaMouse males exposed to procarbazine hydrochloride.Arch Toxicol2023
36646809Error-corrected next-generation sequencing to advance nonclinical genotoxicity and carcinogenicity testing.Nat Rev Drug Discov2023
36881459Considerations for application of benchmark dose modeling in radiation research: workshop highlights.Int J Radiat Biol2023
36754249DNA methylation changes from primary cultures through senescence-bypass in Syrian hamster fetal cells initially exposed to benzo[a]pyrene.Toxicology2023
36534918In vitro transcriptomic analyses reveal pathway perturbations, estrogenic activities, and potencies of data-poor BPA alternative chemicals.Toxicol Sci2023
37491114Error-corrected duplex sequencing enables direct detection and quantification of mutations in human TK6 cells with strong inter-laboratory consistency.Mutat Res Genet Toxicol Environ Mutagen2023
37491114Error-corrected duplex sequencing enables direct detection and quantification of mutations in human TK6 cells with strong inter-laboratory consistency.Mutat Res Genet Toxicol Environ Mutagen2023
38058303The functional mutational landscape of the <i>lacZ</i> gene.iScience2023
37889188Report of the 3rd and 4th Mystery of Reactive Oxygen Species Conference.ALTEX2023
37941476Toxicological Mechanisms and Potencies of Organophosphate Esters in KGN Human Ovarian Granulosa Cells as Revealed by High-throughput Transcriptomics.Toxicol Sci2023
37341741Duplex sequencing provides detailed characterization of mutation frequencies and spectra in the bone marrow of MutaMouse males exposed to procarbazine hydrochloride.Arch Toxicol2023
36754249DNA methylation changes from primary cultures through senescence-bypass in Syrian hamster fetal cells initially exposed to benzo[a]pyrene.Toxicology2023
36881459Considerations for application of benchmark dose modeling in radiation research: workshop highlights.Int J Radiat Biol2023
36646809Error-corrected next-generation sequencing to advance nonclinical genotoxicity and carcinogenicity testing.Nat Rev Drug Discov2023
35247516R-ODAF: Omics data analysis framework for regulatory application.Regul Toxicol Pharmacol2022
35902794Duplex sequencing identifies genomic features that determine susceptibility to benzo(a)pyrene-induced in vivo mutations.BMC Genomics2022
35445829Comprehensive interpretation of in vitro micronucleus test results for 292 chemicals: from hazard identification to risk assessment application.Arch Toxicol2022
36165699A Transformative Vision for an Omics-Based Regulatory Chemical Testing Paradigm.Toxicol Sci2022
35573988Brief Developmental Exposure to Fluoxetine Causes Life-Long Alteration of the Brain Transcriptome in Zebrafish.Front Endocrinol (Lausanne)2022
35573276A Case Study on Integrating a New Key Event Into an Existing Adverse Outcome Pathway on Oxidative DNA Damage: Challenges and Approaches in a Data-Rich Area.Front Toxicol2022
35435297Introducing AOP Reports: Collaborative review and publication of adverse outcome pathways.Environ Mol Mutagen2022
36211197Integrated Genotoxicity Testing of three anti-infective drugs using the TGx-DDI transcriptomic biomarker and high-throughput CometChip<sup>®</sup> assay in TK6 cells.Front Toxicol2022
35939396Evaluating the influences of confounding variables on benchmark dose using a case study in the field of ionizing radiation.Int J Radiat Biol2022
35939275Benchmark dose modeling of transcriptional data: a systematic approach to identify best practices for study designs used in radiation research.Int J Radiat Biol2022
35939057Deploying elements of scoping review methods for adverse outcome pathway development: a space travel case example.Int J Radiat Biol2022
35875696Reactive Oxygen Species in the Adverse Outcome Pathway Framework: Toward Creation of Harmonized Consensus Key Events.Front Toxicol2022
36271823Impact of sampling time on the detection of mutations in rapidly proliferating tissues using transgenic rodent gene mutation models: A review.Environ Mol Mutagen2022
35404422A Collaborative Initiative to Establish Genomic Biomarkers for Assessing Tumorigenic Potential to Reduce Reliance on Conventional Rodent Carcinogenicity Studies.Toxicol Sci2022
35777453A gene expression biomarker identifies inhibitors of two classes of epigenome effectors in a human microarray compendium.Chem Biol Interact2022
35315142AOP report: Development of an adverse outcome pathway for oxidative DNA damage leading to mutations and chromosomal aberrations.Environ Mol Mutagen2022
35247516R-ODAF: Omics data analysis framework for regulatory application.Regul Toxicol Pharmacol2022
35404422A Collaborative Initiative to Establish Genomic Biomarkers for Assessing Tumorigenic Potential to Reduce Reliance on Conventional Rodent Carcinogenicity Studies.Toxicol Sci2022
35435297Introducing AOP Reports: Collaborative review and publication of adverse outcome pathways.Environ Mol Mutagen2022
35573988Brief Developmental Exposure to Fluoxetine Causes Life-Long Alteration of the Brain Transcriptome in Zebrafish.Front Endocrinol (Lausanne)2022
35573276A Case Study on Integrating a New Key Event Into an Existing Adverse Outcome Pathway on Oxidative DNA Damage: Challenges and Approaches in a Data-Rich Area.Front Toxicol2022
35777453A gene expression biomarker identifies inhibitors of two classes of epigenome effectors in a human microarray compendium.Chem Biol Interact2022
35445829Comprehensive interpretation of in vitro micronucleus test results for 292 chemicals: from hazard identification to risk assessment application.Arch Toxicol2022
35875696Reactive Oxygen Species in the Adverse Outcome Pathway Framework: Toward Creation of Harmonized Consensus Key Events.Front Toxicol2022
36211197Integrated Genotoxicity Testing of three anti-infective drugs using the TGx-DDI transcriptomic biomarker and high-throughput CometChip<sup>®</sup> assay in TK6 cells.Front Toxicol2022
35939396Evaluating the influences of confounding variables on benchmark dose using a case study in the field of ionizing radiation.Int J Radiat Biol2022
35939275Benchmark dose modeling of transcriptional data: a systematic approach to identify best practices for study designs used in radiation research.Int J Radiat Biol2022
35939057Deploying elements of scoping review methods for adverse outcome pathway development: a space travel case example.Int J Radiat Biol2022
35902794Duplex sequencing identifies genomic features that determine susceptibility to benzo(a)pyrene-induced in vivo mutations.BMC Genomics2022
36271823Impact of sampling time on the detection of mutations in rapidly proliferating tissues using transgenic rodent gene mutation models: A review.Environ Mol Mutagen2022
36165699A Transformative Vision for an Omics-Based Regulatory Chemical Testing Paradigm.Toxicol Sci2022
35315142AOP report: Development of an adverse outcome pathway for oxidative DNA damage leading to mutations and chromosomal aberrations.Environ Mol Mutagen2022
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Collaborators

Francesco Marchetti
Carleton University
Co-authored papers 44
George R Douglas
Harvard Medical School, Beth Israel Hospital
Co-authored papers 33
Albert J Fornace
Co-authored papers 12
Ivy D Moffat
University of Toronto
Co-authored papers 10
Russell S Thomas
Co-authored papers 9
Scott S Auerbach
National Institute of Environmental Health Sciences
Co-authored papers 8
Michael D Waters
Washington University School of Medicine
Co-authored papers 6
Christopher M Somers
University of Regina
Co-authored papers 5
Weida Tong
National Center for Toxicological Research
Co-authored papers 4
David M DeMarini
Center for Environmental Measurement and Modeling
Co-authored papers 4
Kristine L Witt
National Institute of Environmental Health Sciences/National Institutes of Health
Co-authored papers 4
Jörg Hackermüller
Co-authored papers 4
Yuri E Dubrova
University of Leicester
Co-authored papers 3
Bernard Robaire
McGill University
Co-authored papers 3
Jack B Bishop
National Institute of Environmental Health Sciences
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Barbara F Hales
McGill University
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Matthew E Hurles
Wellcome Sanger Institute
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Lyle D Burgoon
National Center for Environmental Assessment
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James R Lupski
Baylor College of Medicine
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Thomas E Wilson
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Catherine B Klein
New York University School of Medicine
Co-authored papers 2
Rosalie K Elespuru
Center for Devices and Radiological Health
Co-authored papers 2
Melvin E Andersen
Co-authored papers 2
Jennifer Fostel
National Institute of Environmental Health Sciences
Co-authored papers 2
Pierre R Bushel
Co-authored papers 2
Edward J Perkins
Co-authored papers 2
Afshin Beheshti
Co-authored papers 2
Jette Bornholdt
University of Copenhagen
Co-authored papers 2
Wendie A Robbins
University of California Los Angeles
Co-authored papers 1
John J Mulvihill
University of Oklahoma
Co-authored papers 1
Release 1.2