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Author Details

Yi Zheng
Children's Hospital Research Foundation
1993
341
80
PMIDPaper TitleJournal TitlePublished Year
36308434Visualization of preimplantation uterine fluid absorption in mice using Alexa Fluorâ¿¢ 488 Hydrazideâ¿ .Biol Reprod2023
37664630MIF-like domain containing protein orchestrates cellular differentiation and virulence in the fungal pathogen <i>Magnaporthe oryzae</i>.iScience2023
37582970MAVS-loaded unanchored Lys63-linked polyubiquitin chains activate the RIG-I-MAVS signaling cascade.Cell Mol Immunol2023
37532788Kinase-independent role of mTOR and on-/off-target effects of an mTOR kinase inhibitor.Leukemia2023
37345464Latexin deletion protects against radiation-induced hematopoietic damages via selective activation of Bcl-2 prosurvival pathway.Haematologica2023
37043352Mechanism of inert inflammation in an immune checkpoint blockade-resistant tumor subtype bearing transcription elongation defects.Cell Rep2023
37477258Increased apoptosis of gingival epithelium is associated with impaired autophagic flux in medication-related osteonecrosis of the jaw.Autophagy2023
37226238CCP5 and CCP6 retain CP110 and negatively regulate ciliogenesis.BMC Biol2023
36586552Rac is required for the survival of cortical neurons.Exp Neurol2023
36577883Silencing RPL8 inhibits the progression of hepatocellular carcinoma by down-regulating the mTORC1 signalling pathway.Hum Cell2023
36835579Structure-Activity Relationship Analysis of Rhosin, a RhoA GTPase Inhibitor, Reveals a New Class of Antiplatelet Agents.Int J Mol Sci2023
36768837Rho GTPase Signaling in Platelet Regulation and Implication for Antiplatelet Therapies.Int J Mol Sci2023
36681781CD-NTase family member MB21D2 promotes cGAS-mediated antiviral and antitumor immunity.Cell Death Differ2023
36661340A critical role of RUNX1 in governing megakaryocyte-primed hematopoietic stem cell differentiation.Blood Adv2023
33440922Aging of human hematopoietic stem cells is linked to changes in Cdc42 activity.Haematologica2022
35397519MicroRNA-455-3p regulates proliferation and osteoclast differentiation of RAW264.7 cells by targeting PTEN.BMC Musculoskelet Disord2022
35862735Erythroblastic islands foster granulopoiesis in parallel to terminal erythropoiesis.Blood2022
36581635Transplanting rejuvenated blood stem cells extends lifespan of aged immunocompromised mice.NPJ Regen Med2022
36433940Integration of single-cell transcriptomes and biological function reveals distinct behavioral patterns in bone marrow endothelium.Nat Commun2022
36427906Targeting of Cdc42 GTPase in regulatory T cells unleashes antitumor T-cell immunity.J Immunother Cancer2022
36028484The protein arginine methyltransferase PRMT9 attenuates MAVS activation through arginine methylation.Nat Commun2022
36050480USP3 deubiquitinates and stabilizes the adapter protein ASC to regulate inflammasome activation.Cell Mol Immunol2022
36050459Rac-deficient cerebellar granule neurons die before they migrate to the internal granule layer.Sci Rep2022
35942861Novel blood derived hemostatic agents for bleeding therapy and prophylaxis.Curr Opin Hematol2022
35276089Aging of intestinal stem cells.Stem Cell Reports2022
35021092CDC42 controlled apical-basal polarity regulates intestinal stem cell to transit amplifying cell fate transition via YAP-EGF-mTOR signaling.Cell Rep2022
35103877Angiopoietin-2-induced lymphatic endothelial cell migration drives lymphangiogenesis via the β1 integrin-RhoA-formin axis.Angiogenesis2022
34308530Target-Based In Silico Screening for Phytoactive Compounds Targeting SARS-CoV-2.Interdiscip Sci2022
33443202Adaptive responses to <i>mTOR</i> gene targeting in hematopoietic stem cells reveal a proliferative mechanism evasive to mTOR inhibition.Proc Natl Acad Sci U S A2021
33847429An aged bone marrow niche restrains rejuvenated hematopoietic stem cells.Stem Cells2021
33870147Suppression of elevated Cdc42 activity promotes the regenerative potential of aged intestinal stem cells.iScience2021
33497604Structure of an inactive conformation of GTP-bound RhoA GTPase.Structure2021
35116265SAV1, regulated by HERC4, inhibits the proliferation, migration, and invasion of hepatocellular carcinoma.Transl Cancer Res2021
34473945Germline DDX41 mutations cause ineffective hematopoiesis and myelodysplasia.Cell Stem Cell2021
34759029Modulation of Both Intrinsic and Extrinsic Factors Additively Promotes Rewiring of Corticospinal Circuits after Spinal Cord Injury.J Neurosci2021
34661963Cdc42-Borg4-Septin7 axis regulates HSC polarity and function.EMBO Rep2021
34721389Graded RhoA GTPase Expression in Treg Cells Distinguishes Tumor Immunity From Autoimmunity.Front Immunol2021
34321317Targeting multiple cell death pathways extends the shelf life and preserves the function of human and mouse neutrophils for transfusion.Sci Transl Med2021
34036285Protocol for structural and biochemical analyses of RhoA GTPase.STAR Protoc2021
34292326The chromatin remodeler CHD8 governs hematopoietic stem/progenitor survival by regulating ATM-mediated P53 protein stability.Blood2021
34362877TRIM31 facilitates K27-linked polyubiquitination of SYK to regulate antifungal immunity.Signal Transduct Target Ther2021
34194524Metabonomic Study on the Plasma of High-Fat Diet-Induced Dyslipidemia Rats Treated with Ge Gen Qin Lian Decoction by Ultrahigh-Performance Liquid Chromatography-Mass Spectrometry.Evid Based Complement Alternat Med2021
34162972Pharmacologic targeting of Cdc42 GTPase by a small molecule Cdc42 activity-specific inhibitor prevents platelet activation and thrombosis.Sci Rep2021
33247486Antioxidant prevents clearance of hemostatically competent platelets after long-term cold storage.Transfusion2021
33302008Psychrozymes as novel tools to biodegrade p-xylene and potential use for contaminated groundwater in the cold climate.Bioresour Technol2021
31171637Latexin regulation by HMGB2 is required for hematopoietic stem cell maintenance.Haematologica2020
32075226Mdm2 and MdmX RING Domains Play Distinct Roles in the Regulation of p53 Responses: A Comparative Study of Mdm2 and MdmX RING Domains in U2OS Cells.Int J Mol Sci2020
31911614Publisher Correction: The long non-coding RNA HOXB-AS3 regulates ribosomal RNA transcription in NPM1-mutated acute myeloid leukemia.Nat Commun2020
32709223MicroRNA-410-3p modulates chondrocyte apoptosis and inflammation by targeting high mobility group box 1 (HMGB1) in an osteoarthritis mouse model.BMC Musculoskelet Disord2020
32728019Author Correction: The long non-coding RNA HOXB-AS3 regulates ribosomal RNA transcription in NPM1-mutated acute myeloid leukemia.Nat Commun2020
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Collaborators

Kun Guo
Co-authored papers 39
Jose A Cancelas
Cincinnati Children's Hospital Medical Center
Co-authored papers 31
Cheryl H Arrowsmith
University of Toronto
Co-authored papers 13
Jorge Silvio Gutkind
Moores Cancer Center, University of California San Diego
Co-authored papers 10
Tak W Mak
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Co-authored papers 6
Jarek Meller
Co-authored papers 6
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Co-authored papers 5
Yaqin Zhang
Jiangsu University Zhenjiang 212013
Co-authored papers 4
Jacek Biesiada
Co-authored papers 4
Phuong Nguyen
Hoag Memorial Hospital Presbyterian
Co-authored papers 4
Brian Raught
Princess Margaret Cancer Centre, University Health Network
Co-authored papers 3
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the Princess Margaret Cancer Centre, University Health Network
Co-authored papers 3
Krzysztof Mr??zek
The Ohio State Comprehensive Cancer Center
Co-authored papers 3
Clinton H Joiner
Emory University School of Medicine
Co-authored papers 3
Oliver M Dovey
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Linda Z Penn
University of Toronto
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Eric Wang
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Guillermo Garcia-Manero
MD Anderson Cancer Center
Co-authored papers 3
Jie J Zheng
Molecular Biology Institute, University of California los angeles
Co-authored papers 3
Sirano Dhe-Paganon
Dana-Farber Cancer Institute
Co-authored papers 3
Andrew J Elia
University Health Network, Princess Margaret Cancer Centre
Co-authored papers 3
Guramrit Singh
Co-authored papers 3
Daniel Y L Mao
Lunenfeld-Tanenbaum Research Institute
Co-authored papers 2
Paul C Boutros
University of California los angeles
Co-authored papers 2
Otto Sanchez
Ontario Tech University
Co-authored papers 2
Razqallah Hakem
Princess Margaret Cancer Centre, University Health Network, University of Toronto
Co-authored papers 2
Chuan He
Institute of Hematology, West China Hospital of Sichuan University
Co-authored papers 2
Matthew T Weirauch
University of Cincinnati College of Medicine
Co-authored papers 2
Maria Sunnerhagen
Linkoping University
Co-authored papers 2
William C Reinhold
Center for Cancer Research, National Cancer Institute
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Release 1.2