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Author Details

Siraj M Ali
Foundation Medicine
1995
329
74
Trey Ideker (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36082904Comprehensive Landscape of Cyclin Pathway Gene Alterations and Co-occurrence with FGF/FGFR Aberrations Across Urinary Tract Tumors.Oncologist2023
35176763The Genomics of Colorectal Cancer in Populations with African and European Ancestry.Cancer Discov2022
35584350Clustered 8-Oxo-Guanine Mutations and Oncogenic Gene Fusions in Microsatellite-Unstable Colorectal Cancer.JCO Precis Oncol2022
35705558Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma.Nat Commun2022
35580297AENEAS: A Randomized Phase III Trial of Aumolertinib Versus Gefitinib as First-Line Therapy for Locally Advanced or MetastaticNon-Small-Cell Lung Cancer With <i>EGFR</i> Exon 19 Deletion or L858R Mutations.J Clin Oncol2022
35970994Activating IGF1R hotspot non-frameshift insertions define a novel, potentially targetable molecular subtype of adenoid cystic carcinoma.Mod Pathol2022
36050473Publisher Correction: Truncated FGFR2 is a clinically actionable oncogene in multiple cancers.Nature2022
36253270A Common Cell of Origin for Inflammatory Myofibroblastic Tumor and Lung Adenocarcinoma with ALK rearrangement.Clin Lung Cancer2022
35176763The Genomics of Colorectal Cancer in Populations with African and European Ancestry.Cancer Discov2022
31412008Comprehensive Genomic Profiling of Adult Renal Sarcomas Provides Insight into Disease Biology and Opportunities for Targeted Therapies.Eur Urol Oncol2021
33522043Landscape of Cyclin Pathway Genomic Alterations Across 5,356 Prostate Cancers: Implications for Targeted Therapeutics.Oncologist2021
33654076Structure-function analysis of oncogenic EGFR Kinase Domain Duplication reveals insights into activation and a potential approach for therapeutic targeting.Nat Commun2021
33542076Optimized EGFR Blockade Strategies in <i>EGFR</i> Addicted Gastroesophageal Adenocarcinomas.Clin Cancer Res2021
33542076Optimized EGFR Blockade Strategies in <i>EGFR</i> Addicted Gastroesophageal Adenocarcinomas.Clin Cancer Res2021
33775530Comprehensive genomic profiling of metastatic collecting duct carcinoma, renal medullary carcinoma, and clear cell renal cell carcinoma.Urol Oncol2021
34950838Positive Association Between Location of Melanoma, Ultraviolet Signature, Tumor Mutational Burden, and Response to Anti-PD-1 Therapy.JCO Precis Oncol2021
34463133Real-world association of HER2/<i>ERBB2</i> concordance with trastuzumab clinical benefit in advanced esophagogastric cancer.Future Oncol2021
34476330Genomic Profiling of Combined Hepatocellular Cholangiocarcinoma Reveals Genomics Similar to Either Hepatocellular Carcinoma or Cholangiocarcinoma.JCO Precis Oncol2021
34077268Clinicopathologic Features and Response to Therapy of <i>NRG1</i> Fusion-Driven Lung Cancers: The eNRGy1 Global Multicenter Registry.J Clin Oncol2021
34215504Comprehensive genomic profiling of histologic subtypes of urethral carcinomas.Urol Oncol2021
34333275Genomic profiling of solid tumors harboring BRD4-NUT and response to immune checkpoint inhibitors.Transl Oncol2021
32061548Urothelial Cancers with Small Cell Variant Histology Have Confirmed High Tumor Mutational Burden, Frequent TP53 and RB Mutations, and a Unique Gene Expression Profile.Eur Urol Oncol2021
32918774Targetable BRAF and RAF1 Alterations in Advanced Pediatric Cancers.Oncologist2021
32861617Comprehensive Genomic Profiling of Upper-tract and Bladder Urothelial Carcinoma.Eur Urol Focus2021
32885893Cyclin Pathway Genomic Alterations Across 190,247 Solid Tumors: Leveraging Large-Scale Data to Inform Therapeutic Directions.Oncologist2021
32516377Predicting the Pathologic Complete Response After Neoadjuvant Pembrolizumab in Muscle-Invasive Bladder Cancer.J Natl Cancer Inst2021
31578273Tumor Mutational Burden as a Predictive Biomarker for Response to Immune Checkpoint Inhibitors: A Review of Current Evidence.Oncologist2020
31959546Comprehensive Assessment of Immuno-oncology Biomarkers in Adenocarcinoma, Urothelial Carcinoma, and Squamous-cell Carcinoma of the Bladder.Eur Urol2020
31988001Clinicopathologic Characteristics of BRG1-Deficient NSCLC.J Thorac Oncol2020
31985116Urothelial cancer harbours EGFR and HER2 amplifications and exon 20 insertions.BJU Int2020
31882336Squamous Transformation of Prostate Adenocarcinoma: A Report of Two Cases With Genomic Profiling.Clin Genitourin Cancer2020
31882281Multiparametric Magnetic Resonance Imaging as a Noninvasive Assessment of Tumor Response to Neoadjuvant Pembrolizumab in Muscle-invasive Bladder Cancer: Preliminary Findings from the PURE-01 Study.Eur Urol2020
31708296Updated Results of PURE-01 with Preliminary Activity of Neoadjuvant Pembrolizumab in Patients with Muscle-invasive Bladder Carcinoma with Variant Histologies.Eur Urol2020
33046892Targetable gene fusions and aberrations in genitourinary oncology.Nat Rev Urol2020
33097651Responsiveness to immune checkpoint inhibitors versus other systemic therapies in RET-aberrant malignancies.ESMO Open2020
32966992Characterization of Clinical Cases of Malignant PEComa via Comprehensive Genomic Profiling of DNA and RNA.Oncology2020
32823229Retrospective analysis of real-world data to determine clinical outcomes of patients with advanced non-small cell lung cancer following cell-free circulating tumor DNA genomic profiling.Lung Cancer2020
32903788Pan-Cancer Analysis of <i>BRCA1</i> and <i>BRCA2</i> Genomic Alterations and Their Association With Genomic Instability as Measured by Genome-Wide Loss of Heterozygosity.JCO Precis Oncol2020
32393201Recurrent secondary genomic alterations in desmoplastic small round cell tumors.BMC Med Genet2020
32144050Unfavorable Cancer-specific Survival After Neoadjuvant Chemotherapy and Radical Cystectomy in Patients With Bladder Cancer and Squamous Cell Variant: A Multi-institutional Study.Clin Genitourin Cancer2020
32464188Clinical and Genomic Characteristics of Small Cell Lung Cancer in Never Smokers: Results From a Retrospective Multicenter Cohort Study.Chest2020
32399016Exceptional Response to Everolimus in a Patient with Metastatic Castrate-Resistant Prostate Cancer Harboring a PTEN Inactivating Mutation.Case Rep Oncol2020
32368168Patients with NSCLCs Harboring Internal Inversions or Deletion Rearrangements of the <i>ALK</i> Gene Have Durable Responses to ALK Kinase Inhibitors.Lung Cancer (Auckl)2020
32156473Genomic profiling of BCOR-rearranged uterine sarcomas reveals novel gene fusion partners, frequent CDK4 amplification and CDKN2A loss.Gynecol Oncol2020
30025711Genomic Characterization of Testicular Germ Cell Tumors Relapsing After Chemotherapy.Eur Urol Focus2020
31604903The Pan-Cancer Landscape of Coamplification of the Tyrosine Kinases KIT, KDR, and PDGFRA.Oncologist2020
30380541A Pan-Cancer Landscape Analysis Reveals a Subset of Endometrial Stromal and Pediatric Tumors Defined by Internal Tandem Duplications of BCOR.Oncology2019
35100719Atypical <i>RAS</i> Mutations in Metastatic Colorectal Cancer.JCO Precis Oncol2019
35100719Atypical <i>RAS</i> Mutations in Metastatic Colorectal Cancer.JCO Precis Oncol2019
35100669Acquired <i>CTNNB1</i> Mutation Drives Immune Checkpoint Inhibitor-Acquired Resistance in a Microsatellite Instability-High Gastroesophageal Adenocarcinoma With Brain Metastases.JCO Precis Oncol2019
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Collaborators

Foundation Medicine
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Injury Prevention Research Center, University of North Carolina
Co-authored papers 192
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Foundation Medicine Inc
Co-authored papers 15
Whitehead Institute for Biomedical Research and Massachusetts Institute of Technology
Co-authored papers 9
Samsung Medical Center, Sungkyunkwan University School of Medicine
Co-authored papers 8
From Foundation Medicine
Co-authored papers 7
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Co-authored papers 6
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Co-authored papers 6
UF Health Cancer Center
Co-authored papers 5
Busan Paik Hospital, Inje University
Co-authored papers 5
IRCCS San Raffaele Scientific Institute
Co-authored papers 5
Dana-Farber Cancer Institute
Co-authored papers 5
Weill Cornell School of Medicine
Co-authored papers 4
Memorial Sloan Kettering Cancer Center
Co-authored papers 4
University of California san francisco
Co-authored papers 4
Vanderbilt University
Co-authored papers 4
Hospital Israelita Albert Einstein
Co-authored papers 4
University of California Davis Comprehensive Cancer Center
Co-authored papers 4
Massachusetts General Hospital/Harvard Medical School
Co-authored papers 3
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IRCCS San Raffaele Scientific Institute, Italy Vita-Salute San Raffaele University
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Neuroscience Institute, NYU Grossman School of Medicine
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Yonsei Cancer Center, Yonsei University College of Medicine
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