Author details

Full Name

Huixiao Hong

Affiliation

ORCID

Career Start Year

1997

Papers

188

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37516343	Analyzing 3D structures of the SARS-CoV-2 main protease reveals structural features of ligand binding for COVID-19 drug discovery.		2023
37679543	Multi-omics data integration using ratio-based quantitative profiling with Quartet reference materials.	Nat Biotechnol	2023
37679545	Quartet RNA reference materials improve the quality of transcriptomic data through ratio-based profiling.	Nat Biotechnol	2023
37674217	Correcting batch effects in large-scale multiomics studies using a reference-material-based ratio method.	Genome Biol	2023
38012772	Quartet DNA reference materials and datasets for comprehensively evaluating germline variant calling performance.	Genome Biol	2023
37997891	Developing a SARS-CoV-2 main protease binding prediction random forest model for drug repurposing for COVID-19 treatment.		2023
37887023	Deep Learning Methods for Omics Data Imputation.		2023
37884999	The Quartet Data Portal: integration of community-wide resources for multiomics quality control.	Genome Biol	2023
37783850	Author Correction: Quartet RNA reference materials improve the quality of transcriptomic data through ratio-based profiling.	Nat Biotechnol	2023
38062992	Assessments of tumor mutational burden estimation by targeted panel sequencing: A comprehensive simulation analysis.	Exp Biol Med (Maywood)	2023
38057999	Review of machine learning and deep learning models for toxicity prediction.		2023
36835186	Distinct Conformations of SARS-CoV-2 Omicron Spike Protein and Its Interaction with ACE2 and Antibody.		2023
37108204	Three-Dimensional Structural Insights Have Revealed the Distinct Binding Interactions of Agonists, Partial Agonists, and Antagonists with the Âµ Opioid Receptor.		2023
34996510	Achieving robust somatic mutation detection with deep learning models derived from reference data sets of a cancer sample.	Genome Biol	2022
35905417	Whole Exome Sequencing Reveals Genetic Variants in HLA Class II Genes Associated With Transplant-free Survival of Indeterminate Acute Liver Failure.	Clinical and Translational Gastroenterology	2022
36238576	Machine learning models for rat multigeneration reproductive toxicity prediction.	Frontiers in Pharmacology	2022
36234502	Deep Learning Models for Predicting Gas Adsorption Capacity of Nanomaterials.	Nanomaterials	2022
36406474	An autoencoder-based deep learning method for genotype imputation.	Frontiers in Artificial Intelligence	2022
35296201	Integrative approaches for studying the role of noncoding RNAs in influencing drug efficacy and toxicity.	Expert Opin Drug Metab Toxicol	2022
34980216	Assessing reproducibility of inherited variants detected with short-read whole genome sequencing.	Genome Biol	2022
35029374	Machine Learning Models for Predicting Cytotoxicity of Nanomaterials.	Chemical Research in Toxicology	2022
35188640	Machine Learning Models for Predicting Liver Toxicity.	Methods Mol Biol	2022
35157438	Correction to Structures of Endocrine-Disrupting Chemicals Determine Binding to and Activation of the Estrogen Receptor Î± and Androgen Receptor.	Environmental Science & Technology	2022
34872606	The SEQC2 epigenomics quality control (EpiQC) study.	Genome Biol	2021
33914508	Developing QSAR Models with Defined Applicability Domains on PPARÎ³ Binding Affinity Using Large Data Sets and Machine Learning Algorithms.	Environmental Science & Technology	2021
34234253	Informing selection of drugs for COVID-19 treatment through adverse events analysis.	Sci Rep	2021
33964751	Human transthyretin binding affinity of halogenated thiophenols and halogenated phenols: An in vitro and in silico study.		2021
34281077	Machine Learning for Predicting Risk of Drug-Induced Autoimmune Diseases by Structural Alerts and Daily Dose.	Int J Environ Res Public Health	2021
33525602	Software-Assisted Pattern Recognition of Persistent Organic Pollutants in Contaminated Human and Animal Food.	Molecules	2021
34047186	Predictive Models to Identify Small Molecule Activators and Inhibitors of Opioid Receptors.	Journal of Chemical Information and Modeling	2021
34207026	Nanomaterial Databases: Data Sources for Promoting Design and Risk Assessment of Nanomaterials.	Nanomaterials	2021
33925388	Identification of Epidemiological Traits by Analysis of SARS-CoV-2 Sequences.	Viruses	2021
33863344	Cross-oncopanel study reveals high sensitivity and accuracy with overall analytical performance depending on genomic regions.	Genome Biol	2021
34859678	Structures of Endocrine-Disrupting Chemicals Correlate with the Activation of 12 Classic Nuclear Receptors.	Environmental Science & Technology	2021
34504347	Establishing community reference samples, data and call sets for benchmarking cancer mutation detection using whole-genome sequencing.	Nat Biotechnol	2021
34504346	Toward best practice in cancer mutation detection with whole-genome and whole-exome sequencing.	Nat Biotechnol	2021
34502280	Elucidation of Agonist and Antagonist Dynamic Binding Patterns in ER-Î± by Integration of Molecular Docking, Molecular Dynamics Simulations and Quantum Mechanical Calculations.	International Journal of Molecular Sciences	2021
34949218	Author Correction: The SEQC2 epigenomics quality control (EpiQC) study.	Genome Biol	2021
34930391	Hidden biases in germline structural variant detection.	Genome Biol	2021
34756375	Development of classification models for predicting inhibition of mitochondrial fusion and fission using machine learning methods.		2020
32074470	CoMPARA: Collaborative Modeling Project for Androgen Receptor Activity.	Environ Health Perspect	2020
32017538	Applicability Domains Enhance Application of PPARÎ³ Agonist Classifiers Trained by Drug-like Compounds to Environmental Chemicals.	Chemical Research in Toxicology	2020
32159345	Development of a Nicotinic Acetylcholine Receptor nAChR Î±7 Binding Activity Prediction Model.	Journal of Chemical Information and Modeling	2020
32464767	Discriminant models on mitochondrial toxicity improved by consensus modeling and resolving imbalance in training.		2020
33469527	Elucidating Interactions Between SARS-CoV-2 Trimeric Spike Protein and ACE2 Using Homology Modeling and Molecular Dynamics Simulations.	Frontiers in Chemistry	2020
33372637	Structure-activity relationship-based chemical classification of highly imbalanced Tox21 datasets.	Journal of Cheminformatics	2020
32749457	A comprehensive rat transcriptome built from large scale RNA-seq-based annotation.	Nucleic Acids Res	2020
32692251	Quantitative Structure-Activity Relationship Models for Predicting Inflammatory Potential of Metal Oxide Nanoparticles.	Environ Health Perspect	2020
33021389	Reproducibility challenges for biomarker detection with uncertain but informative experimental data.	Biomarkers in Medicine	2020
32786601	Structures of Endocrine-Disrupting Chemicals Determine Binding to and Activation of the Estrogen Receptor Î± and Androgen Receptor.	Environmental Science & Technology	2020