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Author Details

Jared V Goldstone
Woods Hole Oceanographic Institution
2002
69
32
PMIDPaper TitleJournal TitlePublished Year
37209461Structural modeling of cytochrome P450 51 from a deep-sea fish points to a novel structural feature in other CYP51s.J Inorg Biochem2023
34427654Resolving the Rules of Robustness and Resilience in Biology Across Scales.Integr Comp Biol2022
35801640Metabolic arsenal of giant viruses: Host hijack or self-use?Elife2022
36009001Characterization of a Virally Encoded Flavodoxin That Can Drive Bacterial Cytochrome P450 Monooxygenase Activity.Biomolecules2022
33429071Resistance to Cyp3a induction by polychlorinated biphenyls, including non-dioxin-like PCB153, in gills of killifish (Fundulus heteroclitus) from New Bedford Harbor.Environ Toxicol Pharmacol2021
34903767Orphan cytochrome P450 20a1 CRISPR/Cas9 mutants and neurobehavioral phenotypes in zebrafish.Sci Rep2021
34561524Developmental exposure to non-dioxin-like polychlorinated biphenyls promotes sensory deficits and disrupts dopaminergic and GABAergic signaling in zebrafish.Commun Biol2021
34006915The chemical defensome of five model teleost fish.Sci Rep2021
33972594The cytochrome P450 (CYP) superfamily in cnidarians.Sci Rep2021
33031537Concerning P450 Evolution: Structural Analyses Support Bacterial Origin of Sterol 14α-Demethylases.Mol Biol Evol2021
31868891CRISPR-Cas9-Mutated Pregnane X Receptor (pxr) Retains Pregnenolone-induced Expression of cyp3a65 in Zebrafish (Danio rerio) Larvae.Toxicol Sci2020
30371853Sequence Variations in pxr (nr1i2) From Zebrafish (Danio rerio) Strains Affect Nuclear Receptor Function.Toxicol Sci2019
31167942On the occurrence of cytochrome P450 in viruses.Proc Natl Acad Sci U S A2019
30321412Developmental Regulation of Nuclear Factor Erythroid-2 Related Factors (nrfs) by AHR1b in Zebrafish (Danio rerio).Toxicol Sci2019
28694077Molecular adaptation to high pressure in cytochrome P450 1A and aryl hydrocarbon receptor systems of the deep-sea fish Coryphaenoides armatus.Biochim Biophys Acta Proteins Proteom2018
29991818Independent losses of a xenobiotic receptor across teleost evolution.Sci Rep2018
28582729The role of Nrf1 and Nrf2 in the regulation of glutathione and redox dynamics in the developing zebrafish embryo.Redox Biol2017
28267574Applying evolutionary genetics to developmental toxicology and risk assessment.Reprod Toxicol2017
28942070Ryanodine receptor and FK506 binding protein 1 in the Atlantic killifish (Fundulus heteroclitus): A phylogenetic and population-based comparison.Aquat Toxicol2017
26853319Cytochrome P450 20A1 in zebrafish: Cloning, regulation and potential involvement in hyperactivity disorders.Toxicol Appl Pharmacol2016
26432395Genetic and structural analyses of cytochrome P450 hydroxylases in sex hormone biosynthesis: Sequential origin and subsequent coevolution.Mol Phylogenet Evol2016
27136924Biochemical Mechanisms for Geographical Adaptations to Novel Toxin Exposures in Butterflyfish.PLoS One2016
26987287Sex-dependent expression of anti-Müllerian hormone (amh) and amh receptor 2 during sex organ differentiation and characterization of the Müllerian duct development in Xenopus tropicalis.Gen Comp Endocrinol2016
25546006Expression and function of ryanodine receptor related pathways in PCB tolerant Atlantic killifish (Fundulus heteroclitus) from New Bedford Harbor, MA, USA.Aquat Toxicol2015
26231923Functional characterization of zebrafish cytochrome P450 1 family proteins expressed in yeast.Biochim Biophys Acta2015
25680588Environmental contaminants activate human and polar bear (Ursus maritimus) pregnane X receptors (PXR, NR1I2) differently.Toxicol Appl Pharmacol2015
25424564Role of pregnane X receptor and aryl hydrocarbon receptor in transcriptional regulation of pxr, CYP2, and CYP3 genes in developing zebrafish.Toxicol Sci2015
24361620Identification, modeling and ligand affinity of early deuterostome CYP51s, and functional characterization of recombinant zebrafish sterol 14α-demethylase.Biochim Biophys Acta2014
23297357The cytochrome P450 genesis locus: the origin and evolution of animal cytochrome P450s.Philos Trans R Soc Lond B Biol Sci2013
24298298Developmental expression of the Nfe2-related factor (Nrf) transcription factor family in the zebrafish, Danio rerio.PLoS One2013
24121122Functional characterization of a full length pregnane X receptor, expression in vivo, and identification of PXR alleles, in zebrafish (Danio rerio).Aquat Toxicol2013
23598338The African coelacanth genome provides insights into tetrapod evolution.Nature2013
23770340Glutathione redox dynamics and expression of glutathione-related genes in the developing embryo.Free Radic Biol Med2013
23726801The cytochrome P450 2AA gene cluster in zebrafish (Danio rerio): expression of CYP2AA1 and CYP2AA2 and response to phenobarbital-type inducers.Toxicol Appl Pharmacol2013
23277104Identification and expression of multiple CYP1-like and CYP3-like genes in the bivalve mollusk Mytilus edulis.Aquat Toxicol2013
22174413Nrf2b, novel zebrafish paralog of oxidant-responsive transcription factor NF-E2-related factor 2 (NRF2).J Biol Chem2012
22669670Methodological approaches to cytochrome P450 profiling in embryos.Methods Mol Biol2012
22356696EZR1: a novel family of highly expressed retroelements induced by TCDD and regulated by a NF-κB-like factor in embryos of zebrafish (Danio rerio).Zebrafish2012
20963850Species extrapolation for the 21st century.Environ Toxicol Chem2011
21840383Structural features of cytochrome P450 1A associated with the absence of EROD activity in liver of the loricariid catfish Pterygoplichthys sp.Gene2011
21354474Cytochrome P450 1A, 1B, and 1C mRNA induction patterns in three-spined stickleback exposed to a transient and a persistent inducer.Comp Biochem Physiol C Toxicol Pharmacol2011
21464924Evolution of a major drug metabolizing enzyme defect in the domestic cat and other felidae: phylogenetic timing and the role of hypercarnivory.PLoS One2011
21130899Cytochrome P450 CYP2 genes in the common cormorant: Evolutionary relationships with 130 diapsid CYP2 clan sequences and chemical effects on their expression.Comp Biochem Physiol C Toxicol Pharmacol2011
20965207New CYP1 genes in the frog Xenopus (Silurana) tropicalis: induction patterns and effects of AHR agonists during development.Toxicol Appl Pharmacol2011
19926125Identification of CYP genes in Mytilus (mussel) and Crassostrea (oyster) species: first approach to the full complement of cytochrome P450 genes in bivalves.Mar Environ Res2010
21087487Identification and developmental expression of the full complement of Cytochrome P450 genes in Zebrafish.BMC Genomics2010
21122142Cytochrome P450 diversity and induction by gorgonian allelochemicals in the marine gastropod Cyphoma gibbosum.BMC Ecol2010
20864627Caenorhabditis elegans generates biologically relevant levels of genotoxic metabolites from aflatoxin B1 but not benzo[a]pyrene in vivo.Toxicol Sci2010
20546934The role of multixenobiotic transporters in predatory marine molluscs as counter-defense mechanisms against dietary allelochemicals.Comp Biochem Physiol C Toxicol Pharmacol2010
20189255Induction of cytochrome P450 1 genes and stress response genes in developing zebrafish exposed to ultraviolet radiation.Aquat Toxicol2010
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Collaborators

Woods Hole Oceanographic Institution
Co-authored papers 48
Woods Hole Oceanographic Institution
Co-authored papers 14
University of Tennessee Health Science Center
Co-authored papers 7
Hopkins Marine Station of Stanford University
Co-authored papers 2
The University of North Texas Health Science Center at Fort Worth
Co-authored papers 2
Scripps Institution of Oceanography, university of california san diego
Co-authored papers 2
National Cancer Institute
Co-authored papers 2
University of California Davis
Co-authored papers 2
University of Texas Rio Grande Valley, 1201 West University Drive
Co-authored papers 2
National Center for Biotechnology Information, National Institutes of Health
Co-authored papers 1
Uppsala University
Co-authored papers 1
Universitat de Barcelona
Co-authored papers 1
Salk Institute for Biological Studies
Co-authored papers 1
Institut Biology Valrose, Universite Cote d'Azur
Co-authored papers 1
Auburn University
Co-authored papers 1
Duke University
Co-authored papers 1
Eastern Michigan University.
Co-authored papers 1
University of Utah
Co-authored papers 1
Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology
Co-authored papers 1
University of California berkeley
Co-authored papers 1
National Institute of Child Health and Human Development
Co-authored papers 1
Baylor College of Medicine
Co-authored papers 1
Co-authored papers 1
Baylor College of Medicine
Co-authored papers 1
Co-authored papers 1
National Center for Biotechnology Information, National Institutes of Health
Co-authored papers 1
Co-authored papers 1
Macquarie University
Co-authored papers 1
Instituto Cajal
Co-authored papers 1
The Affiliated Yantai Yuhuangding Hospital, Qingdao University
Co-authored papers 1