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Author Details

Komal S Rathi
Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia
2014
34
16
PMIDPaper TitleJournal TitlePublished Year
37235472Macrophages in SHH subgroup medulloblastoma display dynamic heterogeneity that varies with treatment modality.Cell Rep2023
37235472Macrophages in SHH subgroup medulloblastoma display dynamic heterogeneity that varies with treatment modality.Cell Rep2023
37492101OpenPBTA: The Open Pediatric Brain Tumor Atlas.Cell Genom2023
37492101OpenPBTA: The Open Pediatric Brain Tumor Atlas.Cell Genom2023
34510780Targeted gene expression profiling of inverted papilloma and squamous cell carcinoma.Int Forum Allergy Rhinol2022
36167467Development of GPC2-directed chimeric antigen receptors using mRNA for pediatric brain tumors.J Immunother Cancer2022
35482926Mitochondrial mutations alter endurance exercise response and determinants in mice.Proc Natl Acad Sci U S A2022
36322731Combination of common mtDNA variants results in mitochondrial dysfunction and a connective tissue dysregulation.Proc Natl Acad Sci U S A2022
36381237Evaluation of the DLL3-targeting antibody-drug conjugate rovalpituzumab tesirine in preclinical models of neuroblastoma.Cancer Res Commun2022
34510780Targeted gene expression profiling of inverted papilloma and squamous cell carcinoma.Int Forum Allergy Rhinol2022
34551968<i>MYC</i> Levels Regulate Metastatic Heterogeneity in Pancreatic Adenocarcinoma.Cancer Discov2022
35482926Mitochondrial mutations alter endurance exercise response and determinants in mice.Proc Natl Acad Sci U S A2022
36167467Development of GPC2-directed chimeric antigen receptors using mRNA for pediatric brain tumors.J Immunother Cancer2022
36381237Evaluation of the DLL3-targeting antibody-drug conjugate rovalpituzumab tesirine in preclinical models of neuroblastoma.Cancer Res Commun2022
36322731Combination of common mtDNA variants results in mitochondrial dysfunction and a connective tissue dysregulation.Proc Natl Acad Sci U S A2022
34551968<i>MYC</i> Levels Regulate Metastatic Heterogeneity in Pancreatic Adenocarcinoma.Cancer Discov2022
34337560A GPC2 antibody-drug conjugate is efficacious against neuroblastoma and small-cell lung cancer via binding a conformational epitope.Cell Rep Med2021
33789113Macrophages in SHH subgroup medulloblastoma display dynamic heterogeneity that varies with treatment modality.Cell Rep2021
33523558Epigenetic regulator BMI1 promotes alveolar rhabdomyosarcoma proliferation and constitutes a novel therapeutic target.Mol Oncol2021
33602789GAS7 Deficiency Promotes Metastasis in MYCN-Driven Neuroblastoma.Cancer Res2021
34337560A GPC2 antibody-drug conjugate is efficacious against neuroblastoma and small-cell lung cancer via binding a conformational epitope.Cell Rep Med2021
33602789GAS7 Deficiency Promotes Metastasis in MYCN-Driven Neuroblastoma.Cancer Res2021
33789113Macrophages in SHH subgroup medulloblastoma display dynamic heterogeneity that varies with treatment modality.Cell Rep2021
33523558Epigenetic regulator BMI1 promotes alveolar rhabdomyosarcoma proliferation and constitutes a novel therapeutic target.Mol Oncol2021
32211329CAMKV Is a Candidate Immunotherapeutic Target in <i>MYCN</i> Amplified Neuroblastoma.Front Oncol2020
31911672Diagnosing Cornelia de Lange syndrome and related neurodevelopmental disorders using RNA sequencing.Genet Med2020
32339949LIN28B promotes neuroblastoma metastasis and regulates PDZ binding kinase.Neoplasia2020
32045996NASA GeneLab Platform Utilized for Biological Response to Space Radiation in Animal Models.Cancers (Basel)2020
32096864Mitochondrial DNA Haplogroups and Susceptibility to Neuroblastoma.J Natl Cancer Inst2020
32211329CAMKV Is a Candidate Immunotherapeutic Target in <i>MYCN</i> Amplified Neuroblastoma.Front Oncol2020
33317447annoFuse: an R Package to annotate, prioritize, and interactively explore putative oncogenic RNA fusions.BMC Bioinformatics2020
33242417Comprehensive Multi-omics Analysis Reveals Mitochondrial Stress as a Central Biological Hub for Spaceflight Impact.Cell2020
32796005Somatic structural variation targets neurodevelopmental genes and identifies <i>SHANK2</i> as a tumor suppressor in neuroblastoma.Genome Res2020
33119584A transcriptome-based classifier to determine molecular subtypes in medulloblastoma.PLoS Comput Biol2020
32045996NASA GeneLab Platform Utilized for Biological Response to Space Radiation in Animal Models.Cancers (Basel)2020
32096864Mitochondrial DNA Haplogroups and Susceptibility to Neuroblastoma.J Natl Cancer Inst2020
31911672Diagnosing Cornelia de Lange syndrome and related neurodevelopmental disorders using RNA sequencing.Genet Med2020
33317447annoFuse: an R Package to annotate, prioritize, and interactively explore putative oncogenic RNA fusions.BMC Bioinformatics2020
33242417Comprehensive Multi-omics Analysis Reveals Mitochondrial Stress as a Central Biological Hub for Spaceflight Impact.Cell2020
33119584A transcriptome-based classifier to determine molecular subtypes in medulloblastoma.PLoS Comput Biol2020
32796005Somatic structural variation targets neurodevelopmental genes and identifies <i>SHANK2</i> as a tumor suppressor in neuroblastoma.Genome Res2020
32339949LIN28B promotes neuroblastoma metastasis and regulates PDZ binding kinase.Neoplasia2020
31133068Clinical utility of custom-designed NGS panel testing in pediatric tumors.Genome Med2019
31693904Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design.Cell Rep2019
31672841YAP1 Mediates Resistance to MEK1/2 Inhibition in Neuroblastomas with Hyperactivated RAS Signaling.Cancer Res2019
31618756The ADP/ATP translocase drives mitophagy independent of nucleotide exchange.Nature2019
31133068Clinical utility of custom-designed NGS panel testing in pediatric tumors.Genome Med2019
30755224PRIMA-1<sup>MET</sup>-induced neuroblastoma cell death is modulated by p53 and mycn through glutathione level.J Exp Clin Cancer Res2019
31072830Targeting PARP-1 with Alpha-Particles Is Potently Cytotoxic to Human Neuroblastoma in Preclinical Models.Mol Cancer Ther2019
31015346OBI-3424, a Novel AKR1C3-Activated Prodrug, Exhibits Potent Efficacy against Preclinical Models of T-ALL.Clin Cancer Res2019
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Collaborators

John M Maris
Children's Hospital of Philadelphia
Co-authored papers 16
Pichai Raman
Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia
Co-authored papers 14
Daniel Martinez
Perelman School of Medicine at the University of Pennsylvania
Co-authored papers 9
Adam C Resnick
Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia
Co-authored papers 5
Kristopher R Bosse
Co-authored papers 5
Phillip B Storm
Children's Hospital of Philadelphia
Co-authored papers 5
Krutika S Gaonkar
Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia
Co-authored papers 5
Sharon J Diskin
Children's Hospital of Philadelphia
Co-authored papers 4
Douglas C Wallace
Co-authored papers 4
Gonzalo L??pez
Children's Hospital of Philadelphia
Co-authored papers 4
Jaclyn N Taroni
Alex's Lemonade Stand Foundation
Co-authored papers 4
Casey S Greene
Dartmouth College Geisel School of Medicine, Princeton University, University of Colorado Anschutz Medical Campus, University of Pennsylvania Perelman School of Medicine
Co-authored papers 4
Deanne Taylor
Co-authored papers 4
Malcolm A Smith
National Cancer Institute
Co-authored papers 4
Zalman Vaksman
Children's Hospital of Philadelphia
Co-authored papers 4
Maria V Lane
Co-authored papers 4
Ian W Folkert
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 3
Hakon Hakonarson
The Center for Applied Genomics, Children's Hospital of Philadelphia
Co-authored papers 3
Alvin Farrel
Children's Hospital of Philadelphia
Co-authored papers 3
Candace L Savonen
Johns Hopkins Bloomberg School of Public Health
Co-authored papers 3
Mariarita Santi
Children's Hospital of Philadelphia
Co-authored papers 3
Nathan M Kendsersky
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 3
Mateusz Koptyra
Children's Hospital of Philadelphia
Co-authored papers 3
Yael P Mosse
Perelman School of Medicine at the University of Pennsylvania
Co-authored papers 3
Yuankun Zhu
Children's Hospital of Philadelphia
Co-authored papers 2
Kateryna Krytska
University of Pennsylvania Perelman School of Medicine
Co-authored papers 2
Md Zahidul Alam
Perelman School of Medicine, University of Pennsylvania
Co-authored papers 2
Robert Meller
Co-authored papers 2
Gary Hardiman
Institute for Global Food Security, Queen's University Belfast
Co-authored papers 2
Gregory P Way
Broad Institute of MIT and Harvard
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