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Author Details

Tokameh Mahmoudi
Erasmus University Medical Center
1999
52
25
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
36921041The BAF complex inhibitor pyrimethamine reverses HIV-1 latency in people with HIV-1 on antiretroviral therapy.Sci Adv2023
37663575The efficacy and tolerability of latency-reversing agents in reactivating the HIV-1 reservoir in clinical studies: a systematic review.J Virus Erad2023
37938000Hepatitis C virus infects and perturbs liver stem cells.mBio2023
37224225Non-muscle-invasive bladder cancer molecular subtypes predict differential response to intravesical Bacillus Calmette-Guérin.Sci Transl Med2023
36123995Ten decadal advances in fungal biology leading towards human well-being.Fungal Divers2022
35774399HibeRNAtion: HIV-1 RNA Metabolism and Viral Latency.Front Cell Infect Microbiol2022
35800100Production of Recombinant Hepatitis B virus (HBV) and Detection of HBV in Infected Human Liver Organoids.Bio Protoc2022
35769258DEAD-ly Affairs: The Roles of DEAD-Box Proteins on HIV-1 Viral RNA Metabolism.Front Cell Dev Biol2022
35434190Generation, Maintenance and HBV Infection of Human Liver Organoids.Bio Protoc2022
34162831Clinical stage drugs targeting inhibitor of apoptosis proteins purge episomal Hepatitis B viral genome in preclinical models.Cell Death Dis2021
33684433Evolution of organoid technology: Lessons learnt in Co-Culture systems from developmental biology.Dev Biol2021
336759833D human liver organoids: An in vitro platform to investigate HBV infection, replication and liver tumorigenesis.Cancer Lett2021
33931637Selective cell death in HIV-1-infected cells by DDX3 inhibitors leads to depletion of the inducible reservoir.Nat Commun2021
34872356A Two-Color Haploid Genetic Screen Identifies Novel Host Factors Involved in HIV-1 Latency.mBio2021
34328417Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma.Elife2021
32702640Towards the next step: LoViRet patients for HIV-1 cure studies.EBioMedicine2020
31756409Development of C-TILDA: A modified TILDA method for reservoir quantification in long term treated patients infected with subtype C HIV-1.J Virol Methods2020
32887284Inter-Laboratory Reproducibility of Inducible HIV-1 Reservoir Quantification by TILDA.Viruses2020
32851167Gliotoxin, identified from a screen of fungal metabolites, disrupts 7SK snRNP, releases P-TEFb, and reverses HIV-1 latency.Sci Adv2020
30366100T cell toxicity of HIV latency reversing agents.Pharmacol Res2019
31323521A broad drug arsenal to attack a strenuous latent HIV reservoir.Curr Opin Virol2019
29343578A New Quinoline BRD4 Inhibitor Targets a Distinct Latent HIV-1 Reservoir for Reactivation from Other "Shock" Drugs.J Virol2018
30197195Small Molecule Targeting of Specific BAF (mSWI/SNF) Complexes for HIV Latency Reversal.Cell Chem Biol2018
29507875Allele-specific long-distance regulation dictates IL-32 isoform switching and mediates susceptibility to HIV-1.Sci Adv2018
29305013Transcription: Insights From the HIV-1 Promoter.Int Rev Cell Mol Biol2018
28069134The Multifaceted Contributions of Chromatin to HIV-1 Integration, Transcription, and Latency.Int Rev Cell Mol Biol2017
28170393Correction: The Leukemia-Associated Mllt10/Af10-Dot1l Are Tcf4/β-Catenin Coactivators Essential for Intestinal Homeostasis.PLoS Biol2017
26870822Small Molecule Inhibitors of BAF; A Promising Family of Compounds in HIV-1 Latency Reversal.EBioMedicine2015
26569493Correction: Repressive LTR Nucleosome Positioning by the BAF Complex Is Required for HIV Latency.PLoS Biol2015
25421889HIV eradication: combinatorial approaches to activate latent viruses.Viruses2014
23469003Znf202 affects high density lipoprotein cholesterol levels and promotes hepatosteatosis in hyperlipidemic mice.PLoS One2013
23696748HDAC7 is a repressor of myeloid genes whose downregulation is required for transdifferentiation of pre-B cells into macrophages.PLoS Genet2013
23658527Wnt signaling regulates the lineage differentiation potential of mouse embryonic stem cells through Tcf3 down-regulation.PLoS Genet2013
22682247Wnt signaling through inhibition of β-catenin degradation in an intact Axin1 complex.Cell2012
22997486Epigenetic regulation of B lymphocyte differentiation, transdifferentiation, and reprogramming.Comp Funct Genomics2012
22771990The BAF complex and HIV latency.Transcription2012
22140357Repressive LTR nucleosome positioning by the BAF complex is required for HIV latency.PLoS Biol2011
20128690MAP3K1 functionally interacts with Axin1 in the canonical Wnt signalling pathway.Biol Chem2010
21103407The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/β-catenin coactivators essential for intestinal homeostasis.PLoS Biol2010
19816403The kinase TNIK is an essential activator of Wnt target genes.EMBO J2009
19850932Phosphatidylinositol 3-kinase signaling does not activate the wnt cascade.J Biol Chem2009
17369396Myosin phosphatase dephosphorylates HDAC7, controls its nucleocytoplasmic shuttling, and inhibits apoptosis in thymocytes.Genes Dev2007
17690245Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription.Proc Natl Acad Sci U S A2007
16687403The SWI/SNF chromatin-remodeling complex is a cofactor for Tat transactivation of the HIV promoter.J Biol Chem2006
16002789DNA looping induced by a transcriptional enhancer in vivo.Nucleic Acids Res2005
12858183Metabolic labeling of C. elegans and D. melanogaster for quantitative proteomics.Nat Biotechnol2003
12596906Selective gene regulation by SWI/SNF-related chromatin remodeling factors.Curr Top Microbiol Immunol2003
12853632GAGA facilitates binding of Pleiohomeotic to a chromatinized Polycomb response element.Nucleic Acids Res2003
11927561GAGA can mediate enhancer function in trans by linking two separate DNA molecules.EMBO J2002
11420721Chromatin silencing and activation by Polycomb and trithorax group proteins.Oncogene2001
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Collaborators

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Utrecht University
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Buck Institute for Research on Aging
Co-authored papers 5
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Co-authored papers 1
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Co-authored papers 1
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Co-authored papers 1
Gladstone Institutes
Co-authored papers 1
Co-authored papers 1
Center for Computational Biology, University of California berkeley
Co-authored papers 1
California Pacific Medical Center Research Institute
Co-authored papers 1
Gladstone Institute of Virology
Co-authored papers 1
California Pacific Medical Center Research Institute
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
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Co-authored papers 1
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