Author details

Full Name

Timothy H Bestor

Affiliation

ORCID

Career Start Year

1976

Papers

120

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
32522876	Methylation-directed glycosylation of chromatin factors represses retrotransposon promoters.	Proceedings of the National Academy of Sciences of the United States of America	2020
29482658	Independent functions of DNMT1 and USP7 at replication foci.	Epigenetics Chromatin	2018
29926889	Photochemical conversion of a cytidine derivative to a thymidine analog via [2+2]-cycloaddition.	Photochemical and Photobiological Sciences	2018
30341171	BAH domains and a histone-like motif in DNA methyltransferase 1 (DNMT1) regulate and maintenance methylation .	Journal of Biological Chemistry	2018
28503201	DNA methylation and DNA methyltransferases.	Epigenetics and Chromatin	2017
27252784	Abnormal X chromosome inactivation and sex-specific gene dysregulation after ablation of FBXL10.	Epigenetics and Chromatin	2016
26496195	Protein O-Glucosyltransferase 1 (POGLUT1) Promotes Mouse Gastrulation through Modification of the Apical Polarity Protein CRUMBS2.	PLoS Genetics	2015
25848754	FBXL10 protects Polycomb-bound genes from hypermethylation.	Nature Genetics	2015
25848064	Reply to Wilkinson: Minor role of programmed methylation and demethylation in mammalian development.	Proceedings of the National Academy of Sciences of the United States of America	2015
25368180	Notes on the role of dynamic DNA methylation in mammalian development.	Proceedings of the National Academy of Sciences of the United States of America	2015
26159833	Dnmt3l-knockout donor cells improve somatic cell nuclear transfer reprogramming efficiency.	Reproduction	2015
24991018	Ectopic DNMT3L triggers assembly of a repressive complex for retroviral silencing in somatic cells.	J Virol	2014
25960928	Methylation Abnormalities in Mammary Carcinoma: The Methylation Suicide Hypothesis.	J Cancer Ther	2014
22387999	Ascorbic acid prevents loss of Dlk1-Dio3 imprinting and facilitates generation of all-iPS cell mice from terminally differentiated B cells.	Nat Genet	2012
21163962	Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation.	Science	2011
20488932	Chromatin and sequence features that define the fine and gross structure of genomic methylation patterns.	Genome Res	2010
21124941	The parental non-equivalence of imprinting control regions during mammalian development and evolution.	PLoS Genetics	2010
20868487	Dynamic instability of genomic methylation patterns in pluripotent stem cells.	Epigenetics Chromatin	2010
18521744	BRCA1 promoter methylation is associated with increased mortality among women with breast cancer.	Breast Cancer Research and Treatment	2009
19657014	Mammalian cytosine methylation at a glance.	J Cell Sci	2009
18398312	WAMIDEX: a web atlas of murine genomic imprinting and differential expression.	Epigenetics	2008
18302924	Cytosine methylation: remaining faithful.	Current Biology	2008
18922463	A piRNA pathway primed by individual transposons is linked to de novo DNA methylation in mice.	Molecular Cell	2008
18663141	Extensive meiotic asynapsis in mice antagonises meiotic silencing of unsynapsed chromatin and consequently disrupts meiotic sex chromosome inactivation.	Journal of Cell Biology	2008
18585349	The colorful history of active DNA demethylation.	Cell	2008
17060371	Sex-specific promoters regulate Dnmt3L expression in mouse germ cells.	Hum Reprod	2007
17376869	Hyperconserved CpG domains underlie Polycomb-binding sites.	Proc Natl Acad Sci U S A	2007
17371843	Biological functions of DNA methyltransferase 1 require its methyltransferase activity.	Molecular and Cellular Biology	2007
17942418	Allele-specific demethylation at an imprinted mammalian promoter.	Nucleic Acids Research	2007
17593943	Gene regulation: stochastic and deterministic effects in gene regulation.	Heredity	2007
17211475	The decatenation checkpoint.	British Journal of Cancer	2007
17687327	DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA.	Nature	2007
17446388	Epigenetic decisions in mammalian germ cells.	Science	2007
17445268	Coordinate regulation of DNA methyltransferase expression during oogenesis.	BMC Dev Biol	2007
17395546	MIWI2 is essential for spermatogenesis and repression of transposons in the mouse male germline.	Developmental Cell	2007
17875220	Loss of spermatogonia and wide-spread DNA methylation defects in newborn male mice deficient in DNMT3L.	BMC Dev Biol	2007
16424344	Methylation of tRNAAsp by the DNA methyltransferase homolog Dnmt2.	Science	2006
16575161	Origins of extreme sexual dimorphism in genomic imprinting.	Cytogenetic and Genome Research	2006
16818882	Computational prediction of methylation status in human genomic sequences.	Proceedings of the National Academy of Sciences of the United States of America	2006
16462811	Combing over heritable gene silencing.	Nature Structural and Molecular Biology	2006
16365381	Large-scale structure of genomic methylation patterns.	Genome Research	2006
16501554	Genetics and epigenetics of hydatidiform moles.	Nature Genetics	2006
16479155	Decatenation checkpoint deficiency destabilizes the stem cell genome.	Cell Cycle	2006
16338661	Decatenation checkpoint deficiency in stem and progenitor cells.	Cancer Cell	2005
16096053	Transposons reanimated in mice.	Cell	2005
15811946	Identification of the control region for tissue-specific imprinting of the stimulatory G protein alpha-subunit.	Proceedings of the National Academy of Sciences of the United States of America	2005
15952895	Eukaryotic cytosine methyltransferases.	Annual Review of Biochemistry	2005
15063176	Windows for sex-specific methylation marked by DNA methyltransferase expression profiles in mouse germ cells.	Dev Biol	2004
15318244	Meiotic catastrophe and retrotransposon reactivation in male germ cells lacking Dnmt3L.	Nature	2004
16117671	Transposon silencing and imprint establishment in mammalian germ cells.	Cold Spring Harbor Symposia on Quantitative Biology	2004