Author details

Full Name

Valeriya Lyssenko

Affiliation

ORCID

Career Start Year

2005

Papers

145

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
37452207	Genetics of diabetes-associated microvascular complications.		2023
37034649	Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications.	medRxiv	2023
37137910	Identification of biomarkers for glycaemic deterioration in type 2 diabetes.	Nat Commun	2023
35043148	Spatial Environment Affects HNF4A Mutation-Specific Proteome Signatures and Cellular Morphology in hiPSC-Derived Î²-Like Cells.		2022
35526080	Impaired activation of STAT5 upon IL-2 stimulation in Tregs and elevated sIL-2R in SjÃ¶gren's syndrome.		2022
35551307	Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.	Nat Genet	2022
35600617	Neuronal Dysfunction Is Linked to the Famine-Associated Risk of Proliferative Retinopathy in Patients With Type 2 Diabetes.	Frontiers in Neuroscience	2022
34169655	Perinatal famine is associated with excess risk of proliferative retinopathy in patients with type 2 diabetes.	Acta Ophthalmologica	2022
34376475	Distinct Molecular Signatures of Clinical Clusters in People With Type 2 Diabetes: An IMI-RHAPSODY Study.	Diabetes	2021
34276762	Novel Reclassification of Adult Diabetes Is Useful to Distinguish Stages of Î²-Cell Function Linked to the Risk of Vascular Complications: The DOLCE Study From Northern Ukraine.	Frontiers in Genetics	2021
34110439	Replication and cross-validation of type 2 diabetes subtypes based on clinical variables: an IMI-RHAPSODY study.	Diabetologia	2021
33558525	Publisher Correction: Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.	Nat Commun	2021
33402679	Sex-dimorphic genetic effects and novel loci for fasting glucose and insulin variability.	Nat Commun	2021
34869314	Starvation to Glucose Reprograms Development of Neurovascular Unit in Embryonic Retinal Cells.	Frontiers in Cell and Developmental Biology	2021
34671071	Reduced expression of OXPHOS and DNA damage genes is linked to protection from microvascular complications in long-term type 1 diabetes: the PROLONG study.	Scientific Reports	2021
32665614	Liver nucleotide biosynthesis is linked to protection from vascular complications in individuals with long-term type 1 diabetes.	Sci Rep	2020
31860786	A diabetes-associated genetic variant is associated with diastolic dysfunction and cardiovascular disease.	ESC heart failure	2020
33193091	Increased Plasma Soluble Interleukin-2 Receptor Alpha Levels in Patients With Long-Term Type 1 Diabetes With Vascular Complications Associated With and Gene Polymorphisms.	Frontiers in Endocrinology	2020
31118516	Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls.	Nature	2019
30487263	Multiethnic Genome-Wide Association Study of Diabetic Retinopathy Using Liability Threshold Modeling of Duration of Diabetes and Glycemic Control.	Diabetes	2019
29360107	Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.	Sci Data	2018
30297969	Fine-mapping type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps.	Nat Genet	2018
30178632	A genome-wide association study suggests new evidence for an association of the NADPH Oxidase 4 (NOX4) gene with severe diabetic retinopathy in type 2 diabetes.	Acta Ophthalmol	2018
29703844	A Genome-Wide Association Study of Diabetic Kidney Disease in Subjects With Type 2 Diabetes.	Diabetes	2018
27647854	The Genetic Landscape of Renal Complications in Type 1 Diabetes.	J Am Soc Nephrol	2017
28898252	Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.	PLoS Med	2017
28566273	An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans.	Diabetes	2017
29257133	Sequence data and association statistics from 12,940 type 2 diabetes cases and controls.	Sci Data	2017
29067252	Sense of Coherence is associated with LDL-cholesterol in patients with type 1 diabetes - The PROLONG-Steno study.	Journal of Clinical and Translational Endocrinology	2017
27876822	A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape.	Nat Commun	2016
28326339	Glucose-dependent insulinotropic polypeptide () and GIP receptor () genes: An association analysis of polymorphisms and bone in young and elderly women.	Bone Reports	2016
27440825	Personalized Therapy by Phenotype and Genotype.	Diabetes Care	2016
27338624	CART is overexpressed in human type 2 diabetic islets and inhibits glucagon secretion and increases insulin secretion.	Diabetologia	2016
26959991	A Variant of GJD2, Encoding for Connexin 36, Alters the Function of Insulin Producing Î²-Cells.	PLoS ONE	2016
26998692	Genetic predisposition for beta cell fragility underlies type 1 and type 2 diabetes.	Nat Genet	2016
27355579	Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	PLoS Genet	2016
27398621	The genetic architecture of type 2 diabetes.	Nature	2016
26815880	Atrial Natriuretic Peptide in the High Normal Range Is Associated With Lower Prevalence of Insulin Resistance.	Journal of Clinical Endocrinology and Metabolism	2016
26395740	Glucose-Dependent Insulinotropic Polypeptide Stimulates Osteopontin Expression in the Vasculature via Endothelin-1 and CREB.	Diabetes	2016
27758844	Impact of the TCF7L2 genotype on risk of hypoglycaemia and glucagon secretion during hypoglycaemia.	Endocrine Connections	2016
26426971	The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study.	PLoS Genet	2015
25673413	Genetic studies of body mass index yield new insights for obesity biology.	Nature	2015
25712996	Age- and sex-specific causal effects of adiposity on cardiovascular risk factors.	Diabetes	2015
25673412	New genetic loci link adipose and insulin biology to body fat distribution.	Nature	2015
25961943	The impact of low-frequency and rare variants on lipid levels.	Nat Genet	2015
25948681	Using Genetic Variants to Assess the Relationship Between Circulating Lipids and Type 2 Diabetes.	Diabetes	2015
25719930	Variation in glucose homeostasis traits associated with P2RX7 polymorphisms in mice and humans.	Journal of Clinical Endocrinology and Metabolism	2015
25292440	Modelling of OGTT curve identifies 1 h plasma glucose level as a strong predictor of incident type 2 diabetes: results from two prospective cohorts.	Diabetologia	2015
27111116	Genetics of Type 2 Diabetes: It Matters From Which Parent We Inherit the Risk.	Review of Diabetic Studies	2015
26132169	Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation.	PLoS Genet	2015