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Author Details

Wolf-Dietrich Heyer
University of California davis
1982
135
52
Nevan J Krogan (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37070185Saccharomyces cerevisiae DNA polymerase IV overcomes Rad51 inhibition of DNA polymerase δ in Rad52-mediated direct-repeat recombination.Nucleic Acids Res2023
37541760Delineation of two multi-invasion-induced rearrangement pathways that differently affect genome stability.Genes Dev2023
38045423Multi-Step Control of Homologous Recombination by Mec1/ATR Ensures Robust Suppression of Gross Chromosomal Rearrangements.bioRxiv2023
36993162Delineation of two multi-invasion-induced rearrangement pathways that differently affect genome stability.bioRxiv2023
34707239Publisher Correction: POLθ-mediated end joining is restricted by RAD52 and BRCA2 until the onset of mitosis.Nat Cell Biol2022
36155960Detection of Homologous Recombination Intermediates via Proximity Ligation and Quantitative PCR in Saccharomyces cerevisiae.J Vis Exp2022
32840803Physical and Genetic Assays for the Study of DNA Joint Molecules Metabolism and Multi-invasion-Induced Rearrangements in S. cerevisiae.Methods Mol Biol2021
35419469Turning end-joining upside down in mitosis.Mol Cell Oncol2021
34440403Guardians of the Genome: BRCA2 and Its Partners.Genes (Basel)2021
34616022POLθ-mediated end joining is restricted by RAD52 and BRCA2 until the onset of mitosis.Nat Cell Biol2021
34481156Cancer testis antigens and genomic instability: More than immunology.DNA Repair (Amst)2021
32469862Saccharomyces cerevisiae Mus81-Mms4 prevents accelerated senescence in telomerase-deficient cells.PLoS Genet2020
33185188Rdh54/Tid1 inhibits Rad51-Rad54-mediated D-loop formation and limits D-loop length.Elife2020
33185185Bisulfite treatment and single-molecule real-time sequencing reveal D-loop length, position, and distribution.Elife2020
32609828DSS1 and ssDNA regulate oligomerization of BRCA2.Nucleic Acids Res2020
30652106Guidelines for DNA recombination and repair studies: Mechanistic assays of DNA repair processes.Microb Cell2019
31492866In vitro role of Rad54 in Rad51-ssDNA filament-dependent homology search and synaptic complexes formation.Nat Commun2019
31123771Moving forward one step back at a time: reversibility during homologous recombination.Curr Genet2019
30737186Dynamic Processing of Displacement Loops during Recombinational DNA Repair.Mol Cell2019
31142613Role of the Srs2-Rad51 Interaction Domain in Crossover Control in Saccharomyces cerevisiae.Genetics2019
30818168Cooperation between non-essential DNA polymerases contributes to genome stability in Saccharomyces cerevisiae.DNA Repair (Amst)2019
30497856Homologous Recombination and the Formation of Complex Genomic Rearrangements.Trends Cell Biol2019
29599286Homologous recombination and the repair of DNA double-strand breaks.J Biol Chem2018
29578583Multi-Invasion-Induced Rearrangements as a Pathway for Physiological and Pathological Recombination.Bioessays2018
29523235A Proximity Ligation-Based Method for Quantitative Measurement of D-Loop Extension in S. cerevisiae.Methods Enzymol2018
28535142Srs2 promotes synthesis-dependent strand annealing by disrupting DNA polymerase δ-extending D-loops.Elife2017
28512214Correction for Muñoz-Galván et al., "Distinct Roles of Mus81, Yen1, Slx1-Slx4, and Rad1 Nucleases in the Repair of Replication-Born Double-Strand Breaks by Sister Chromatid Exchange".Mol Cell Biol2017
28781165Multi-invasions Are Recombination Byproducts that Induce Chromosomal Rearrangements.Cell2017
27001511Nonsense-mediated decay regulates key components of homologous recombination.Nucleic Acids Res2016
27893960Eukaryotic DNA Polymerases in Homologous Recombination.Annu Rev Genet2016
27264870Nek1 Regulates Rad54 to Orchestrate Homologous Recombination and Replication Fork Stability.Mol Cell2016
27325747Strand displacement synthesis by yeast DNA polymerase ε.Nucleic Acids Res2016
26830258Autism and Cancer Share Risk Genes, Pathways, and Drug Targets.Trends Genet2016
25765654RAD54 family translocases counter genotoxic effects of RAD51 in human tumor cells.Nucleic Acids Res2015
26607450DNA polymerases δ and λ cooperate in repairing double-strand breaks by microhomology-mediated end-joining in Saccharomyces cerevisiae.Proc Natl Acad Sci U S A2015
26238353Regulation of recombination and genomic maintenance.Cold Spring Harb Perspect Biol2015
25699708Top3-Rmi1 dissolve Rad51-mediated D loops by a topoisomerase-based mechanism.Mol Cell2015
24486020Rad54 functions as a heteroduplex DNA pump modulated by its DNA substrates and Rad51 during D loop formation.Mol Cell2014
24744239The Mus81-Mms4 structure-selective endonuclease requires nicked DNA junctions to undergo conformational changes and bend its DNA substrates for cleavage.Nucleic Acids Res2014
23535143Reconstitution of recombination-associated DNA synthesis with human proteins.Nucleic Acids Res2013
24358152A conserved sequence extending motif III of the motor domain in the Snf2-family DNA translocase Rad54 is critical for ATPase activity.PLoS One2013
23592964Synthetic lethality between gene defects affecting a single non-essential molecular pathway with reversible steps.PLoS Comput Biol2013
22354996Distinct roles of Mus81, Yen1, Slx1-Slx4, and Rad1 nucleases in the repair of replication-born double-strand breaks by sister chromatid exchange.Mol Cell Biol2012
22645308Mus81-Mms4 functions as a single heterodimer to cleave nicked intermediates in recombinational DNA repair.Mol Cell Biol2012
21189297Who's who in human recombination: BRCA2 and RAD52.Proc Natl Acad Sci U S A2011
22020281Rad51 paralogues Rad55-Rad57 balance the antirecombinase Srs2 in Rad51 filament formation.Nature2011
21599536Presynaptic filament dynamics in homologous recombination and DNA repair.Crit Rev Biochem Mol Biol2011
21660705In vitro assays for DNA pairing and recombination-associated DNA synthesis.Methods Mol Biol2011
21660704Assays for structure-selective DNA endonucleases.Methods Mol Biol2011
21660703Quality control of purified proteins involved in homologous recombination.Methods Mol Biol2011
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Collaborators

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Co-authored papers 7
University of Washington
Co-authored papers 6
University of Virginia
Co-authored papers 3
University of California berkeley
Co-authored papers 3
University of Virginia
Co-authored papers 3
TheScripps Research Institute
Co-authored papers 3
Amgen Inc.
Co-authored papers 2
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Co-authored papers 2
University College London
Co-authored papers 2
Eastern Virginia Medical School
Co-authored papers 2
Ecole Polytechnique Federale de Lausanne (EPFL), University of Lausanne
Co-authored papers 2
Harvard Medical School
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
Co-authored papers 1
University of California San Francisco
Co-authored papers 1
Brandeis University
Co-authored papers 1
Institut Curie, Universite PSL
Co-authored papers 1
UPMC-Hillman Cancer Center, University of Pittsburgh
Co-authored papers 1
INSERM U, Institut Curie, PSL Research University
Co-authored papers 1
Weill Institute for Cell and Molecular Biology, Cornell University
Co-authored papers 1
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Kaiser Permanente San Francisco Medical Center
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