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Author Details
Full Name
Douglas A Lauffenburger
Affiliation
Massachusetts Institute of Technology
ORCID
Career Start Year
1979
Papers
557
H Index
102
Expertise
CM4AI Collaborator
Trey Ideker (CM4AI)
PMID
Paper Title
Journal Title
Published Year
36669487
Humoral signatures of MOG-antibody-associated disease track with age and disease activity.
Cell Rep Med
2023
37672567
Humoral immunity to an endemic coronavirus is associated with postacute sequelae of COVID-19 in individuals with rheumatic diseases.
Sci Transl Med
2023
37734322
What cannot be seen correctly in 2D visualizations of single-cell 'omics data?
Cell Syst
2023
38007686
Beta-spike-containing boosters induce robust and functional antibody responses to SARS-CoV-2 in macaques primed with distinct vaccines.
Cell Rep
2023
37577655
Humoral correlates of protection against <i>Mycobacterium tuberculosis</i> following intravenous Bacille Calmette-Guérin vaccination in rhesus macaques.
bioRxiv
2023
37473730
Biphasic JNK-Erk signaling separates the induction and maintenance of cell senescence after DNA damage induced by topoisomerase II inhibition.
Cell Syst
2023
37149863
Vaginal epithelial dysfunction is mediated by the microbiome, metabolome, and mTOR signaling.
Cell Rep
2023
37267955
Airway TÂ cells are a correlate of i.v. Bacille Calmette-Guerin-mediated protection against tuberculosis in rhesus macaques.
Cell Host Microbe
2023
36890168
Systems serology-based comparison of antibody effector functions induced by adjuvanted vaccines to guide vaccine design.
NPJ Vaccines
2023
37200108
Host genetic background is a barrier to broadly effective vaccine-mediated protection against tuberculosis.
J Clin Invest
2023
37322179
ChAdOx1 nCoV-19 (AZD1222) vaccine-induced Fc receptor binding tracks with differential susceptibility to COVID-19.
Nat Immunol
2023
37061918
Antibodies against the Ebola virus soluble glycoprotein are associated with long-term vaccine-mediated protection of non-human primates.
Cell Rep
2023
36805331
Effect of host factors and COVID-19 infection on the humoral immune repertoire in treated HIV.
JCI Insight
2023
36692019
Delayed boosting improves human antigen-specific Ig and B cell responses to the RH5.1/AS01B malaria vaccine.
JCI Insight
2023
37182520
Hybrid immunity expands the functional humoral footprint of both mRNA and vector-based SARS-CoV-2 vaccines.
Cell Rep Med
2023
36737667
Author Correction: Screening for CD19-specific chimaeric antigen receptors with enhanced signalling via a barcoded library of intracellular domains.
Nat Biomed Eng
2023
36922512
Differences in HPV-specific antibody Fc-effector functions following Gardasil® and Cervarix® vaccination.
NPJ Vaccines
2023
36669487
Humoral signatures of MOG-antibody-associated disease track with age and disease activity.
Cell Rep Med
2023
37161609
Neurologic sequelae of COVID-19 are determined by immunologic imprinting from previous coronaviruses.
Brain
2023
38007686
Beta-spike-containing boosters induce robust and functional antibody responses to SARS-CoV-2 in macaques primed with distinct vaccines.
Cell Rep
2023
37577655
Humoral correlates of protection against <i>Mycobacterium tuberculosis</i> following intravenous Bacille Calmette-Guérin vaccination in rhesus macaques.
bioRxiv
2023
37734322
What cannot be seen correctly in 2D visualizations of single-cell 'omics data?
Cell Syst
2023
37672567
Humoral immunity to an endemic coronavirus is associated with postacute sequelae of COVID-19 in individuals with rheumatic diseases.
Sci Transl Med
2023
37061918
Antibodies against the Ebola virus soluble glycoprotein are associated with long-term vaccine-mediated protection of non-human primates.
Cell Rep
2023
37322179
ChAdOx1 nCoV-19 (AZD1222) vaccine-induced Fc receptor binding tracks with differential susceptibility to COVID-19.
Nat Immunol
2023
37149863
Vaginal epithelial dysfunction is mediated by the microbiome, metabolome, and mTOR signaling.
Cell Rep
2023
37182520
Hybrid immunity expands the functional humoral footprint of both mRNA and vector-based SARS-CoV-2 vaccines.
Cell Rep Med
2023
37267955
Airway TÂ cells are a correlate of i.v. Bacille Calmette-Guerin-mediated protection against tuberculosis in rhesus macaques.
Cell Host Microbe
2023
37200108
Host genetic background is a barrier to broadly effective vaccine-mediated protection against tuberculosis.
J Clin Invest
2023
37473730
Biphasic JNK-Erk signaling separates the induction and maintenance of cell senescence after DNA damage induced by topoisomerase II inhibition.
Cell Syst
2023
37161609
Neurologic sequelae of COVID-19 are determined by immunologic imprinting from previous coronaviruses.
Brain
2023
36890168
Systems serology-based comparison of antibody effector functions induced by adjuvanted vaccines to guide vaccine design.
NPJ Vaccines
2023
36922512
Differences in HPV-specific antibody Fc-effector functions following Gardasil® and Cervarix® vaccination.
NPJ Vaccines
2023
36692019
Delayed boosting improves human antigen-specific Ig and B cell responses to the RH5.1/AS01B malaria vaccine.
JCI Insight
2023
36805331
Effect of host factors and COVID-19 infection on the humoral immune repertoire in treated HIV.
JCI Insight
2023
36737667
Author Correction: Screening for CD19-specific chimaeric antigen receptors with enhanced signalling via a barcoded library of intracellular domains.
Nat Biomed Eng
2023
34737186
Regulatory T Cells Control Effector T Cell Inflammation in Human Prediabetes.
Diabetes
2022
35710755
Screening for CD19-specific chimaeric antigen receptors with enhanced signalling via a barcoded library of intracellular domains.
Nat Biomed Eng
2022
35654811
Artificial neural networks enable genome-scale simulations of intracellular signaling.
Nat Commun
2022
35767652
Antibody Fc characteristics and effector functions correlate with protection from symptomatic dengue virus type 3 infection.
Sci Transl Med
2022
35762593
The Kinetics of SARS-CoV-2 Antibody Development Is Associated with Clearance of RNAemia.
mBio
2022
35512013
Defining the determinants of protection against SARS-CoV-2 infection and viral control in a dose-down Ad26.CoV2.S vaccine study in nonhuman primates.
PLoS Biol
2022
36351430
Nucleocapsid-specific antibody function is associated with therapeutic benefits from COVID-19 convalescent plasma therapy.
Cell Rep Med
2022
36000735
Hybrid Immunity Shifts the Fc-Effector Quality of SARS-CoV-2 mRNA Vaccine-Induced Immunity.
mBio
2022
35934070
A multifaceted high-throughput assay for probing antigen-specific antibody-mediated primary monocyte phagocytosis and downstream functions.
J Immunol Methods
2022
35990702
An affinity for brainstem microglia in pediatric high-grade gliomas of brainstem origin.
Neurooncol Adv
2022
35417540
Functional Compartmentalization of Antibodies in the Central Nervous System During Chronic HIV Infection.
J Infect Dis
2022
36056073
Selective transfer of maternal antibodies in preterm and fullterm children.
Sci Rep
2022
35669012
Synthetic extracellular matrices and astrocytes provide a supportive microenvironment for the cultivation and investigation of primary pediatric gliomas.
Neurooncol Adv
2022
35600339
Cancer-Associated Fibroblasts and Squamous Epithelial Cells Constitute a Unique Microenvironment in a Mouse Model of Inflammation-Induced Colon Cancer.
Front Oncol
2022
1 - 50 of 1,114
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