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Author Details
Full Name
Zhe Jiang
Affiliation
Toronto General Research Institute, University Health Network, 67 College Street
ORCID
Career Start Year
1992
Papers
31
H Index
19
Expertise
CM4AI Collaborator
PMID
Paper Title
Journal Title
Published Year
37463901
Distinct shared and compartment-enriched oncogenic networks drive primary versus metastatic breast cancer.
Nat Commun
2023
35023164
Hypophosphorylated pRb knock-in mice exhibit hallmarks of aging and vitamin C-preventable diabetes.
EMBO J
2022
32286280
Modeling germline mutations in pineoblastoma uncovers lysosome disruption-based therapy.
Nat Commun
2020
32064036
Stratifying the stratifiers of triple negative breast cancer.
Oncotarget
2020
31836816
Molecular stratification within triple-negative breast cancer subtypes.
Sci Rep
2019
29617654
Identification of CDC25 as a Common Therapeutic Target for Triple-Negative Breast Cancer.
Cell Rep
2018
30250928
CDC25 as a common therapeutic target for triple-negative breast cancer - the challenges ahead.
Mol Cell Oncol
2018
29120753
Mitochondrial OXPHOS Induced by RB1 Deficiency in Breast Cancer: Implications for Anabolic Metabolism, Stemness, and Metastasis.
Trends Cancer
2017
28215225
Transcription Factors in Breast Cancer-Lessons From Recent Genomic Analyses and Therapeutic Implications.
Adv Protein Chem Struct Biol
2017
27571409
RB1 deficiency in triple-negative breast cancer induces mitochondrial protein translation.
J Clin Invest
2016
24487029
shRNA kinome screen identifies TBK1 as a therapeutic target for HER2+ breast cancer.
Cancer Res
2014
25594009
Targeting HER2(+) breast cancer: the TBK1/IKKε axis.
Oncoscience
2014
23498719
Characterisation of retinoblastomas without RB1 mutations: genomic, gene expression, and clinical studies.
Lancet Oncol
2013
21502814
RB1 and p53 at the crossroad of EMT and triple-negative breast cancer.
Cell Cycle
2011
20679727
Rb deletion in mouse mammary progenitors induces luminal-B or basal-like/EMT tumor subtypes depending on p53 status.
J Clin Invest
2010
15659578
Conserved and specific functions of mammalian ssu72.
Nucleic Acids Res
2005
15843406
The retinoblastoma gene pathway regulates the postmitotic state of hair cells of the mouse inner ear.
Development
2005
15108316
Dynamic regulation of the Stra13/Sharp/Dec bHLH repressors in mammary epithelium.
Dev Dyn
2004
15567721
High expression during neurogenesis but not mammogenesis of a murine homologue of the Deleted in Breast Cancer2/Rhobtb2 tumor suppressor.
Gene Expr Patterns
2004
11777937
Activation of retinoblastoma protein in mammary gland leads to ductal growth suppression, precocious differentiation, and adenocarcinoma.
J Cell Biol
2002
14516658
Coordinated expression of Rb gene family in the mammary gland.
Mech Dev
2002
12617834
Coordinated expression of Rb gene family in the mammary gland.
Gene Expr Patterns
2002
11016928
Retinoblastoma gene promoter directs transgene expression exclusively to the nervous system.
J Biol Chem
2001
11076674
E2F1 and p53 are dispensable, whereas p21(Waf1/Cip1) cooperates with Rb to restrict endoreduplication and apoptosis during skeletal myogenesis.
Dev Biol
2000
10556583
Nuclear localization conferred by the pocket domain of the retinoblastoma gene product.
Biochim Biophys Acta
1999
9150384
The retinoblastoma gene family is differentially expressed during embryogenesis.
Oncogene
1997
8552398
Loss of Rb and Myc activation co-operate to suppress cyclin D1 and contribute to transformation.
Oncogene
1996
8918469
Dual mechanisms of repression of E2F1 activity by the retinoblastoma gene product.
EMBO J
1996
8957005
pRb controls proliferation, differentiation, and death of skeletal muscle cells and other lineages during embryogenesis.
Genes Dev
1996
8346717
Unraveling the function of the retinoblastoma gene.
Adv Cancer Res
1993
1490389
Why don't germline mutations in RB1 predispose to leukemia?
Curr Top Microbiol Immunol
1992
1 - 31 of 31
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Research Institute for Medical and Health Sciences, University of Sharjah
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The Hospital for Sick Children
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Indiana University School of Medicine
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Cancer Center Amsterdam
Co-authored papers
1
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Co-authored papers
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Toronto Western Hospital
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Ontario Institute for Cancer Research, University Avenue
Co-authored papers
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University of Toronto
Co-authored papers
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University of Alberta
Co-authored papers
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Diane Rushlow
Toronto Western Hospital
Co-authored papers
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University of Pennsylvania
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