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Author Details

Zhe Jiang
Toronto General Research Institute, University Health Network, 67 College Street
1992
31
19
PMIDPaper TitleJournal TitlePublished Year
37463901Distinct shared and compartment-enriched oncogenic networks drive primary versus metastatic breast cancer.Nat Commun2023
35023164Hypophosphorylated pRb knock-in mice exhibit hallmarks of aging and vitamin C-preventable diabetes.EMBO J2022
32286280Modeling germline mutations in pineoblastoma uncovers lysosome disruption-based therapy.Nat Commun2020
32064036Stratifying the stratifiers of triple negative breast cancer.Oncotarget2020
31836816Molecular stratification within triple-negative breast cancer subtypes.Sci Rep2019
29617654Identification of CDC25 as a Common Therapeutic Target for Triple-Negative Breast Cancer.Cell Rep2018
30250928CDC25 as a common therapeutic target for triple-negative breast cancer - the challenges ahead.Mol Cell Oncol2018
29120753Mitochondrial OXPHOS Induced by RB1 Deficiency in Breast Cancer: Implications for Anabolic Metabolism, Stemness, and Metastasis.Trends Cancer2017
28215225Transcription Factors in Breast Cancer-Lessons From Recent Genomic Analyses and Therapeutic Implications.Adv Protein Chem Struct Biol2017
27571409RB1 deficiency in triple-negative breast cancer induces mitochondrial protein translation.J Clin Invest2016
24487029shRNA kinome screen identifies TBK1 as a therapeutic target for HER2+ breast cancer.Cancer Res2014
25594009Targeting HER2(+) breast cancer: the TBK1/IKKε axis.Oncoscience2014
23498719Characterisation of retinoblastomas without RB1 mutations: genomic, gene expression, and clinical studies.Lancet Oncol2013
21502814RB1 and p53 at the crossroad of EMT and triple-negative breast cancer.Cell Cycle2011
20679727Rb deletion in mouse mammary progenitors induces luminal-B or basal-like/EMT tumor subtypes depending on p53 status.J Clin Invest2010
15659578Conserved and specific functions of mammalian ssu72.Nucleic Acids Res2005
15843406The retinoblastoma gene pathway regulates the postmitotic state of hair cells of the mouse inner ear.Development2005
15108316Dynamic regulation of the Stra13/Sharp/Dec bHLH repressors in mammary epithelium.Dev Dyn2004
15567721High expression during neurogenesis but not mammogenesis of a murine homologue of the Deleted in Breast Cancer2/Rhobtb2 tumor suppressor.Gene Expr Patterns2004
11777937Activation of retinoblastoma protein in mammary gland leads to ductal growth suppression, precocious differentiation, and adenocarcinoma.J Cell Biol2002
14516658Coordinated expression of Rb gene family in the mammary gland.Mech Dev2002
12617834Coordinated expression of Rb gene family in the mammary gland.Gene Expr Patterns2002
11016928Retinoblastoma gene promoter directs transgene expression exclusively to the nervous system.J Biol Chem2001
11076674E2F1 and p53 are dispensable, whereas p21(Waf1/Cip1) cooperates with Rb to restrict endoreduplication and apoptosis during skeletal myogenesis.Dev Biol2000
10556583Nuclear localization conferred by the pocket domain of the retinoblastoma gene product.Biochim Biophys Acta1999
9150384The retinoblastoma gene family is differentially expressed during embryogenesis.Oncogene1997
8552398Loss of Rb and Myc activation co-operate to suppress cyclin D1 and contribute to transformation.Oncogene1996
8918469Dual mechanisms of repression of E2F1 activity by the retinoblastoma gene product.EMBO J1996
8957005pRb controls proliferation, differentiation, and death of skeletal muscle cells and other lineages during embryogenesis.Genes Dev1996
8346717Unraveling the function of the retinoblastoma gene.Adv Cancer Res1993
1490389Why don't germline mutations in RB1 predispose to leukemia?Curr Top Microbiol Immunol1992
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Collaborators

University of Toronto
Co-authored papers 30
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Co-authored papers 8
College of Pharmaceutical Sciences, Shanghai Jiao Tong University
Co-authored papers 6
University of Toronto
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Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
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Research Institute for Medical and Health Sciences, University of Sharjah
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The Hospital for Sick Children
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Indiana University School of Medicine
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Cancer Center Amsterdam
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Toronto Western Hospital
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University of Toronto
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University of Alberta
Co-authored papers 1
Toronto Western Hospital
Co-authored papers 1
University of Pennsylvania
Co-authored papers 1
Ontario Cancer Institute/Princess Margaret Hospital, University Health Network
Co-authored papers 1
College of Chemistry and Chemical Engineering, Hunan University
Co-authored papers 1
University Health Network, University of Toronto
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VU University Medical Center
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Princess Margaret Cancer Centre, University Health Network
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University of California los angeles
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Institute of Human Genetics, University Hospital Essen, University Duisburg-Essen
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Princess Margaret Cancer Centre
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Ontario Institute for Cancer Research, University Avenue
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Harvard Medical School
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