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Author Details

Stephen J Newhouse
King's College London
2003
79
41
Timothy Clark (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
34345870The effects of genotype on inflammatory response in hippocampal progenitor cells: A computational approach.Brain Behav Immun Health2021
34272080A recessive S174X mutation in Optineurin causes amyotrophic lateral sclerosis through a loss of function via allele-specific nonsense-mediated decay.Neurobiol Aging2021
32573913Genome-wide association study of rate of cognitive decline in Alzheimer's disease patients identifies novel genes and pathways.Alzheimers Dement2020
32065794Working Towards a Blood-Derived Gene Expression Biomarker Specific for Alzheimer's Disease.J Alzheimers Dis2020
33113361Genome-wide Meta-analysis Finds the ACSL5-ZDHHC6 Locus Is Associated with ALS and Links Weight Loss to the Disease Genetics.Cell Rep2020
32745807An epigenome-wide association study of Alzheimer's disease blood highlights robust DNA hypermethylation in the HOXB6 gene.Neurobiol Aging2020
30909231A Meta-Analysis of Alzheimer's Disease Brain Transcriptomic Data.J Alzheimers Dis2019
31315673C9orf72 intermediate expansions of 24-30 repeats are associated with ALS.Acta Neuropathol Commun2019
31596875Genetic associations with radiological damage in rheumatoid arthritis: Meta-analysis of seven genome-wide association studies of 2,775 cases.PLoS One2019
30835568ALSgeneScanner: a pipeline for the analysis and interpretation of DNA sequencing data of ALS patients.Amyotroph Lateral Scler Frontotemporal Degener2019
31063847Transcriptomic analysis of probable asymptomatic and symptomatic alzheimer brains.Brain Behav Immun2019
31113746Differential gene expression analysis in blood of first episode psychosis patients.Schizophr Res2019
28785111Multi-polygenic score approach to trait prediction.Mol Psychiatry2018
30135031Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: Meta-analysis of data from genome-wide association studies.Eur Neuropsychopharmacol2018
29906661Loss of Trem2 in microglia leads to widespread disruption of cell coexpression networks in mouse brain.Neurobiol Aging2018
30171181Polygenic risk score analyses of symptoms and treatment response in an antipsychotic-naive first episode of psychosis cohort.Transl Psychiatry2018
30320231Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder.Commun Biol2018
29715290Exome array analysis of adverse reactions to fluoropyrimidine-based therapy for gastrointestinal cancer.PLoS One2018
29437638<i>g(HbF)</i>: a genetic model of fetal hemoglobin in sickle cell disease.Blood Adv2018
29789371Identification of new risk factors for rolandic epilepsy: CNV at Xp22.31 and alterations at cholinergic synapses.J Med Genet2018
29731509A genome-wide association study for extremely high intelligence.Mol Psychiatry2018
29160301New insights into the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation.Pharmacogenomics J2018
27834776Genetic Risk as a Marker of Amyloid-β and Tau Burden in Cerebrospinal Fluid.J Alzheimers Dis2017
28407095Genetic and environmental risk factors for rheumatoid arthritis in a UK African ancestry population: the GENRA case-control study.Rheumatology (Oxford)2017
28159590Pharmacogenetics of antidepressant response: A polygenic approach.Prog Neuropsychopharmacol Biol Psychiatry2017
28349126Genetics of stroke in a UK African ancestry case-control study: South London Ethnicity and Stroke Study.Neurol Genet2017
28373841Brain Transcriptome Sequencing of a Natural Model of Alzheimer's Disease.Front Aging Neurosci2017
28208064Mitochondrial genes are altered in blood early in Alzheimer's disease.Neurobiol Aging2017
29078306Widespread covariation of early environmental exposures and trait-associated polygenic variation.Proc Natl Acad Sci U S A2017
28591196Trajectories of dementia-related cognitive decline in a large mental health records derived patient cohort.PLoS One2017
27765268An Examination of Polygenic Score Risk Prediction in Individuals With First-Episode Psychosis.Biol Psychiatry2017
27079753Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease.Alzheimers Dement2016
26484910A Pathway Based Classification Method for Analyzing Gene Expression for Alzheimer's Disease Diagnosis.J Alzheimers Dis2016
26443613Quality control, imputation and analysis of genome-wide genotyping data from the Illumina HumanCoreExome microarray.Brief Funct Genomics2016
27936112Genome-Wide Association of Heroin Dependence in Han Chinese.PLoS One2016
27151072Immune signatures and disorder-specific patterns in a cross-disorder gene expression analysis.Br J Psychiatry2016
27244217Association of a Locus in the CAMTA1 Gene With Survival in Patients With Sporadic Amyotrophic Lateral Sclerosis.JAMA Neurol2016
25123647Circulating Proteomic Signatures of Chronological Age.J Gerontol A Biol Sci Med Sci2015
26401776Tract Based Spatial Statistic Reveals No Differences in White Matter Microstructural Organization between Carriers and Non-Carriers of the APOE É¿4 and É¿2 Alleles in Young Healthy Adolescents.J Alzheimers Dis2015
26401708No Evidence to Suggest that the Use of Acetylcholinesterase Inhibitors Confounds the Results of Two Blood-Based Biomarker Studies in Alzheimer's Disease.J Alzheimers Dis2015
26284520A Subset of Cerebrospinal Fluid Proteins from a Multi-Analyte Panel Associated with Brain Atrophy, Disease Classification and Prediction in Alzheimer's Disease.PLoS One2015
26080319Plasma protein biomarkers of Alzheimer's disease endophenotypes in asymptomatic older twins: early cognitive decline and regional brain volumes.Transl Psychiatry2015
25649652Linking Genetics of Brain Changes to Alzheimer's Disease: Sparse Whole Genome Association Scan of Regional MRI Volumes in the ADNI and AddNeuroMed Cohorts.J Alzheimers Dis2015
24121966Candidate blood proteome markers of Alzheimer's disease onset and progression: a systematic review and replication study.J Alzheimers Dis2014
25226301Genetic predisposition to increased blood cholesterol and triglyceride lipid levels and risk of Alzheimer disease: a Mendelian randomization analysis.PLoS Med2014
25402421Calibrating longitudinal cognition in Alzheimer's disease across diverse test batteries and datasets.Neuroepidemiology2014
25150574Alleles that increase risk for type 2 diabetes mellitus are not associated with increased risk for Alzheimer's disease.Neurobiol Aging2014
25104558Assessment of ZnT3 and PSD95 protein levels in Lewy body dementias and Alzheimer's disease: association with cognitive impairment.Neurobiol Aging2014
24768341Alzheimer's disease biomarker discovery using SOMAscan multiplexed protein technology.Alzheimers Dement2014
24732178Pharmacogenetics of pemetrexed combination therapy in lung cancer: pathway analysis reveals novel toxicity associations.Pharmacogenomics J2014
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Collaborators

Richard J B Dobson
Institute of Psychiatry, King's College London
Co-authored papers 40
Hamel Patel
NIHR Maudsley Biomedical Research Centre, King's College London
Co-authored papers 22
Simon Lovestone
Janssen Medical Ltd
Co-authored papers 19
Mark J Caulfield
William Harvey Research Institute, Queen Mary University of London
Co-authored papers 18
Gerome Breen
Institute of Psychiatry, King's College London
Co-authored papers 18
Patricia B Munroe
Co-authored papers 18
Charles Curtis
NIHR Maudsley Biomedical Research Centre, King's College London
Co-authored papers 17
Nilesh J Samani
Co-authored papers 17
Anna F Dominiczak
Co-authored papers 16
John M C Connell
Co-authored papers 14
Martin Farrall
Co-authored papers 13
Andrew Simmons
Institute of Psychiatry, King's College London
Co-authored papers 10
Chris Wallace
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Sang-Hyuk Lee
Seoul National University
Co-authored papers 10
G M Lathrop
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Maris Laan
Co-authored papers 6
Meena Kumari
Co-authored papers 6
Peter McGuffin
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Tim D Spector
King's College London
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Anne Farmer
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Paul F O'Reilly
Icahn School of Medicine at Mount Sinai
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Paul Elliott
Co-authored papers 5
Peter S Braund
Co-authored papers 5
Marcella Rietschel
Central Institute of Mental Health, University of Mannheim
Co-authored papers 5
Susana Eyheramendy
Universidad Adolfo Ibanez
Co-authored papers 5
Panos Deloukas
William Harvey Research Institute, Queen Mary University of London
Co-authored papers 4
Mika Kivimäki
Co-authored papers 4
Toby Johnson
Co-authored papers 4
Amos A Folarin
Institute of Psychiatry, King's College London
Co-authored papers 4
Serena Sanna
Co-authored papers 4
Release 1.2