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Author Details
Full Name
Michael Shales
Affiliation
University of California, USA Quantitative Biosciences Institute (QBI) san francisco
ORCID
Career Start Year
1980
Papers
44
H Index
29
Expertise
CM4AI Collaborator
Trey Ideker (CM4AI)
PMID
Paper Title
Journal Title
Published Year
33303586
Genetic interaction mapping informs integrative structure determination of protein complexes.
Science
2020
32084337
A Quantitative Genetic Interaction Map of HIV Infection.
Mol Cell
2020
30547882
Genetic analysis reveals functions of atypical polyubiquitin chains.
Elife
2018
30077634
Quantitative Yeast Genetic Interaction Profiling of Bacterial Effector Proteins Uncovers a Role for the Human Retromer in Salmonella Infection.
Cell Syst
2018
30118682
An Mtb-Human Protein-Protein Interaction Map Identifies a Switch between Host Antiviral and Antibacterial Responses.
Mol Cell
2018
28446597
The histone variant H2A.Z promotes splicing of weak introns.
Genes Dev
2017
28481362
Genetic interaction mapping in mammalian cells using CRISPR interference.
Nat Methods
2017
25544563
Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.
Mol Cell
2015
26651948
Meta- and Orthogonal Integration of Influenza "OMICs" Data Defines a Role for UBR4 in Virus Budding.
Cell Host Microbe
2015
26118995
Global Mapping of the Inc-Human Interactome Reveals that Retromer Restricts Chlamydia Infection.
Cell Host Microbe
2015
25888283
Differential genetic interactions of yeast stress response MAPK pathways.
Mol Syst Biol
2015
25825871
Genetic interaction mapping reveals a role for the SWI/SNF nucleosome remodeler in spliceosome activation in fission yeast.
PLoS Genet
2015
25501949
Linking tumor mutations to drug responses via a quantitative chemical-genetic interaction map.
Cancer Discov
2015
24842270
Genetic interaction analysis of point mutations enables interrogation of gene function at a residue-level resolution: exploring the applications of high-resolution genetic interaction mapping of point mutations.
Bioessays
2014
25302077
Evolutionarily conserved genetic interactions with budding and fission yeast MutS identify orthologous relationships in mismatch repair-deficient cancer cells.
Genome Med
2014
25010907
Quantitative analysis of triple-mutant genetic interactions.
Nat Protoc
2014
23407553
Quantitative genetic-interaction mapping in mammalian cells.
Nat Methods
2013
24360963
Chemical genetics of rapamycin-insensitive TORC2 in S. cerevisiae.
Cell Rep
2013
23891562
A lipid E-MAP identifies Ubx2 as a critical regulator of lipid saturation and lipid bilayer stress.
Mol Cell
2013
23932120
From structure to systems: high-resolution, quantitative genetic analysis of RNA polymerase II.
Cell
2013
23746449
Systematic triple-mutant analysis uncovers functional connectivity between pathways involved in chromosome regulation.
Cell Rep
2013
22681890
Hierarchical modularity and the evolution of genetic interactomes across species.
Mol Cell
2012
21185072
Phenotypic landscape of a bacterial cell.
Cell
2011
22190034
Global landscape of HIV-human protein complexes.
Nature
2011
20526336
A plasma-membrane E-MAP reveals links of the eisosome with sphingolipid metabolism and endosomal trafficking.
Nat Struct Mol Biol
2010
21127252
Rewiring of genetic networks in response to DNA damage.
Science
2010
20959818
Epistatic relationships reveal the functional organization of yeast transcription factors.
Mol Syst Biol
2010
20952395
Individual lysine acetylations on the N terminus of Saccharomyces cerevisiae H2A.Z are highly but not differentially regulated.
J Biol Chem
2010
19269370
Functional organization of the S. cerevisiae phosphorylation network.
Cell
2009
19470761
An rtt109-independent role for vps75 in transcription-associated nucleosome dynamics.
Mol Cell Biol
2009
19176519
A complex-based reconstruction of the Saccharomyces cerevisiae interactome.
Mol Cell Proteomics
2009
19061648
A genetic interaction map of RNA-processing factors reveals links between Sem1/Dss1-containing complexes and mRNA export and splicing.
Mol Cell
2008
19160513
High-throughput, quantitative analyses of genetic interactions in E. coli.
Nat Methods
2008
18818364
Conservation and rewiring of functional modules revealed by an epistasis map in fission yeast.
Science
2008
17314980
Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map.
Nature
2007
16554755
Global landscape of protein complexes in the yeast Saccharomyces cerevisiae.
Nature
2006
12358429
Splicing and transcription-associated proteins PSF and p54nrb/nonO bind to the RNA polymerase II CTD.
RNA
2002
8710503
Characterization of the interaction between the acidic activation domain of VP16 and the RNA polymerase II initiation factor TFIIB.
Nucleic Acids Res
1996
1646402
Reduced binding of TFIID to transcriptionally compromised mutants of VP16.
Nature
1991
3896517
Extensive homology among the largest subunits of eukaryotic and prokaryotic RNA polymerases.
Cell
1985
6326108
Identification, molecular cloning, and mutagenesis of Saccharomyces cerevisiae RNA polymerase genes.
Proc Natl Acad Sci U S A
1984
6135505
Daunorubicin-resistant Chinese hamster ovary cells expressing multidrug resistance and a cell-surface P-glycoprotein.
Cancer Res
1983
14582161
DNA-mediated transfer of an RNA polymerase II gene: reversion of the temperature-sensitive hamster cell cycle mutant TsAF8 by mammalian DNA.
Mol Cell Biol
1982
7462338
Defective RNA polymerase II in the G1 specific temperature sensitive hamster cell mutant TsAF8.
J Cell Physiol
1980
1 - 44 of 44
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