Author details

Full Name

Jordi Barretina

Affiliation

ORCID

Career Start Year

2000

Papers

H Index

Expertise

CM4AI Collaborator

PMID	Paper Title	Journal Title	Published Year
36748086	Preclinical evaluation of a COVID-19 vaccine candidate based on a recombinant RBD fusion heterodimer of SARS-CoV-2.	iScience	2023
36961816	Integrated CRISPR screening and drug profiling identifies combination opportunities for EGFR, ALK, and BRAF/MEK inhibitors.		2023
36951231	Plasma acylcarnitines and gut-derived aromatic amino acids as sex-specific hub metabolites of the human aging metabolome.		2023
35311898	The effect of external stimulation on functional networks in the aging healthy human brain.	Cereb Cortex	2022
35954997	Multidisciplinary Neuromuscular and Endurance Interventions on Youth Basketball Players: A Systematic Review with Meta-Analysis and Meta-Regression.	International Journal of Environmental Research and Public Health	2022
35353179	Correction to: Whole-brain dynamics in aging: disruptions in functional connectivity and the role of the rich club.	Cerebral Cortex	2022
34621020	E3 ubiquitin ligase Atrogin-1 mediates adaptive resistance to KIT-targeted inhibition in gastrointestinal stromal tumor.	Oncogene	2021
33514598	Obesity-associated deficits in inhibitory control are phenocopied to mice through gut microbiota changes in one-carbon and aromatic amino acids metabolic pathways.	Gut	2021
33350451	Whole-Brain Dynamics in Aging: Disruptions in Functional Connectivity and the Role of the Rich Club.	Cerebral Cortex	2021
32437737	The Aging Imageomics Study: rationale, design and baseline characteristics of the study population.	Mech Ageing Dev	2020
31324888	Targeting FGFR overcomes EMT-mediated resistance in EGFR mutant non-small cell lung cancer.	Oncogene	2019
30559381	Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.	Nature	2019
30643118	Author Correction: Characterization of Nigerian breast cancer reveals prevalent homologous recombination deficiency and aggressive molecular features.	Nat Commun	2019
31173346	Germline variants and somatic mutation signatures of breast cancer across populations of African and European ancestry in the US and Nigeria.	International Journal of Cancer	2019
31068703	The landscape of cancer cell line metabolism.	Nat Med	2019
31068700	Next-generation characterization of the Cancer Cell Line Encyclopedia.	Nature	2019
30327465	Characterization of Nigerian breast cancer reveals prevalent homologous recombination deficiency and aggressive molecular features.	Nat Commun	2018
26825170	EGF816 Exerts Anticancer Effects in Non-Small Cell Lung Cancer by Irreversibly and Selectively Targeting Primary and Acquired Activating Mutations in the EGF Receptor.	Cancer Research	2016
25083769	Identification of ALK gene alterations in urothelial carcinoma.	PLoS One	2014
23589551	Genomic medicine frontier in human solid tumors: prospects and challenges.	J Clin Oncol	2013
24076604	Global chromatin profiling reveals NSD2 mutations in pediatric acute lymphoblastic leukemia.	Nat Genet	2013
23993102	An interactive resource to identify cancer genetic and lineage dependencies targeted by small molecules.	Cell	2013
23858101	NF1 deletion generates multiple subtypes of soft-tissue sarcoma that respond to MEK inhibition.	Molecular Cancer Therapeutics	2013
22105362	PAK1 is a breast cancer oncogene that coordinately activates MAPK and MET signaling.	Oncogene	2012
22811581	Wnt-pathway activation in two molecular classes of hepatocellular carcinoma and experimental modulation by sorafenib.	Clinical Cancer Research	2012
22751462	Gastrointestinal adenocarcinomas of the esophagus, stomach, and colon exhibit distinct patterns of genome instability and oncogenesis.	Cancer Res	2012
22622578	Melanoma genome sequencing reveals frequent PREX2 mutations.	Nature	2012
22460905	The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity.	Nature	2012
21746896	Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer.	Proc Natl Acad Sci U S A	2011
21892161	Genomic sequencing of colorectal adenocarcinomas identifies a recurrent VTI1A-TCF7L2 fusion.	Nat Genet	2011
21764851	Nuclear factor I/B is an oncogene in small cell lung cancer.	Genes Dev	2011
21760589	Functional genomics reveal that the serine synthesis pathway is essential in breast cancer.	Nature	2011
21753790	Advances in sarcoma genomics and new therapeutic targets.	Nat Rev Cancer	2011
20406486	Differential sensitivity of melanoma cell lines with BRAFV600E mutation to the specific Raf inhibitor PLX4032.	J Transl Med	2010
21107320	COT drives resistance to RAF inhibition through MAP kinase pathway reactivation.	Nature	2010
20179022	Integrative analysis of the melanoma transcriptome.	Genome Res	2010
20164920	The landscape of somatic copy-number alteration across human cancers.	Nature	2010
20162573	Strong expression of IGF1R in pediatric gastrointestinal stromal tumors without IGF1R genomic amplification.	International Journal of Cancer	2010
20601955	Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy.	Nat Genet	2010
19755855	Amplification of chromosomal segment 4q12 in non-small cell lung cancer.	Cancer Biol Ther	2009
19647222	Evidence that inositol polyphosphate 4-phosphatase type II is a tumor suppressor that inhibits PI3K signaling.	Cancer Cell	2009
19451690	Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions.	J Clin Invest	2009
19561607	The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer.	Nat Genet	2009
18701503	Focal gains of VEGFA and molecular classification of hepatocellular carcinoma.	Cancer Res	2008
19061646	CDYL bridges REST and histone methyltransferases for gene repression and suppression of cellular transformation.	Mol Cell	2008
18794900	CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity.	Nature	2008
18784837	Functional copy-number alterations in cancer.	PLoS One	2008
18077431	Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma.	Proc Natl Acad Sci U S A	2007
15258189	R5 HIV gp120-mediated cellular contacts induce the death of single CCR5-expressing CD4 T cells by a gp41-dependent mechanism.	J Leukoc Biol	2004
15280778	Immunological and virological study of enfuvirtide-treated HIV-positive patients.	AIDS	2004