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Author Details

Douglas B Kell
Novo Nordisk Foundation Centre for Biosustainability, Technical University of Denmark
1978
397
84
Emma Lundberg (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37207671Increased Levels of Inflammatory and Endothelial Biomarkers in Blood of Long COVID Patients Point to Thrombotic Endothelialitis.Semin Thromb Hemost2024
36963989Cardiovascular and haematological pathology in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS): A role for viruses.Blood Rev2023
37853293Quantitative LC-MS study of compounds found predictive of COVID-19 severity and outcome.Metabolomics2023
37584410Are fibrinaloid microclots a cause of autoimmunity in Long Covid and other post-infection diseases?Biochem J2023
37809592Accelerating discovery: A novel flow cytometric method for detecting fibrin(ogen) amyloid microclots using long COVID as a model.Heliyon2023
37080828Long COVID: pathophysiological factors and abnormalities of coagulation.Trends Endocrinol Metab2023
37278746Relationship between the concentration of ergothioneine in plasma and the likelihood of developing pre-eclampsia.Biosci Rep2023
34817066Engineering ergothioneine production in Yarrowiaâ¿¿lipolytica.FEBS Lett2022
35727444SpeedyGenesXL: an Automated, High-Throughput Platform for the Preparation of Bespoke Ultralarge Variant Libraries for Directed Evolution.Methods Mol Biol2022
35599794Immuno-Thrombotic Complications of COVID-19: Implications for Timing of Surgery and Anticoagulation.Front Surg2022
35598887Membrane transporter identification and modulation via adaptive laboratory evolution.Metab Eng2022
36557171Understanding Functional Redundancy and Promiscuity of Multidrug Transporters in <i>E. coli</i> under Lipophilic Cation Stress.Membranes (Basel)2022
36043493The potential role of ischaemia-reperfusion injury in chronic, relapsing diseases such as rheumatoid arthritis, Long COVID, and ME/CFS: evidence, mechanisms, and therapeutic implications.Biochem J2022
36174604Relative Hypercoagulopathy of the SARS-CoV-2 Beta and Delta Variants when Compared to the Less Severe Omicron Variants Is Related to TEG Parameters, the Extent of Fibrin Amyloid Microclots, and the Severity of Clinical Illness.Semin Thromb Hemost2022
35933347Prevalence of symptoms, comorbidities, fibrin amyloid microclots and platelet pathology in individuals with Long COVID/Post-Acute Sequelae of COVID-19 (PASC).Cardiovasc Diabetol2022
36131342Proteomics of fibrin amyloid microclots in long COVID/post-acute sequelae of COVID-19 (PASC) shows many entrapped pro-inflammatory molecules that may also contribute to a failed fibrinolytic system.Cardiovasc Diabetol2022
36093181Dimethyl fumarate eliminates differentially culturable <i>Mycobacterium tuberculosis</i> in an intranasal murine model of tuberculosis.Front Cell Infect Microbiol2022
36015078The Occurrence of Hyperactivated Platelets and Fibrinaloid Microclots in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS).Pharmaceuticals (Basel)2022
36009997Analysis of a Library of <i>Escherichia coli</i> Transporter Knockout Strains to Identify Transport Pathways of Antibiotics.Antibiotics (Basel)2022
35155966The Role of Lipopolysaccharide-Induced Cell Signalling in Chronic Inflammation.Chronic Stress (Thousand Oaks)2022
35085780Engineering precursor supply for the high-level production of ergothioneine in Saccharomyces cerevisiae.Metab Eng2022
35195253A central role for amyloid fibrin microclots in long COVID/PASC: origins and therapeutic implications.Biochem J2022
33406033A palette of fluorophores that are differentially accumulated by wild-type and mutant strains of <i>Escherichia coli</i>: surrogate ligands for profiling bacterial membrane transporters.Microbiology (Reading)2021
33916824FragNet, a Contrastive Learning-Based Transformer Model for Clustering, Interpreting, Visualizing, and Navigating Chemical Space.Molecules2021
34944436MassGenie: A Transformer-Based Deep Learning Method for Identifying Small Molecules from Their Mass Spectra.Biomolecules2021
34928464Untargeted metabolomics of COVID-19 patient serum reveals potential prognostic markers of both severity and outcome.Metabolomics2021
34673920Intelligent host engineering for metabolic flux optimisation in biotechnology.Biochem J2021
34641370Membrane Transporters Involved in the Antimicrobial Activities of Pyrithione in <i>Escherichia coli</i>.Molecules2021
34577099The Transporter-Mediated Cellular Uptake and Efflux of Pharmaceutical Drugs and Biotechnology Products: How and Why Phospholipid Bilayer Transport Is Negligible in Real Biomembranes.Molecules2021
34425843Persistent clotting protein pathology in Long COVID/Post-Acute Sequelae of COVID-19 (PASC) is accompanied by increased levels of antiplasmin.Cardiovasc Diabetol2021
34447313An Overview of Cell-Based Assay Platforms for the Solute Carrier Family of Transporters.Front Pharmacol2021
34830660TEG<sup>®</sup>, Microclot and Platelet Mapping for Guiding Early Management of Severe COVID-19 Coagulopathy.J Clin Med2021
34328172SARS-CoV-2 spike protein S1 induces fibrin(ogen) resistant to fibrinolysis: implications for microclot formation in COVID-19.Biosci Rep2021
34061167Harnessing the yeast Saccharomyces cerevisiae for the production of fungal secondary metabolites.Essays Biochem2021
34147184A protet-based, protonic charge transfer model of energy coupling in oxidative and photosynthetic phosphorylation.Adv Microb Physiol2021
32231385Effect of L-Ergothioneine on the metabolic plasma profile of the RUPP rat model of pre-eclampsia.PLoS One2020
32051057The biology of ergothioneine, an antioxidant nutraceutical.Nutr Res Rev2020
31865793L-(+)-Ergothioneine Significantly Improves the Clinical Characteristics of Preeclampsia in the Reduced Uterine Perfusion Pressure Rat Model.Hypertension2020
33431037DeepGraphMolGen, a multi-objective, computational strategy for generating molecules with desirable properties: a graph convolution and reinforcement learning approach.J Cheminform2020
33026554An untargeted metabolomics strategy to measure differences in metabolite uptake and excretion by mammalian cell lines.Metabolomics2020
33424834Detection of Citrullinated Fibrin in Plasma Clots of Rheumatoid Arthritis Patients and Its Relation to Altered Structural Clot Properties, Disease-Related Inflammation and Prothrombotic Tendency.Front Immunol2020
33238416Structural Similarities between Some Common Fluorophores Used in Biology, Marketed Drugs, Endogenous Metabolites, and Natural Products.Mar Drugs2020
33153161Erythrocyte, Platelet, Serum Ferritin, and P-Selectin Pathophysiology Implicated in Severe Hypercoagulation and Vascular Complications in COVID-19.Int J Mol Sci2020
33383805Iron Dysregulation and Inflammagens Related to Oral and Gut Health Are Central to the Development of Parkinson's Disease.Biomolecules2020
33231069Automating Cloning by Natural Transformation.ACS Synth Biol2020
33203441Prevalence of readily detected amyloid blood clots in 'unclotted' Type 2 Diabetes Mellitus and COVID-19 plasma: a preliminary report.Cardiovasc Diabetol2020
33290527Deep learning and generative methods in cheminformatics and chemical biology: navigating small molecule space intelligently.Biochem J2020
32574271The Biology of Lactoferrin, an Iron-Binding Protein That Can Help Defend Against Viruses and Bacteria.Front Immunol2020
32823501A Quantitative Survey of Bacterial Persistence in the Presence of Antibiotics: Towards Antipersister Antimicrobial Discovery.Antibiotics (Basel)2020
32751155VAE-Sim: A Novel Molecular Similarity Measure Based on a Variational Autoencoder.Molecules2020
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Collaborators

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Co-authored papers 43
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Co-authored papers 34
University of Cambridge
Co-authored papers 32
The Manchester Institute of Biotechnology, The University of Manchester
Co-authored papers 22
University of Cape Town
Co-authored papers 16
Co-authored papers 11
Institute for Systems Biology
Co-authored papers 7
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Co-authored papers 7
Institute of Systems, University of Liverpool
Co-authored papers 7
Co-authored papers 7
Babraham Institute
Co-authored papers 5
University of Manchester
Co-authored papers 4
The University of Manchester
Co-authored papers 4
Manchester Institute of Biotechnology, University of Manchester
Co-authored papers 4
Co-authored papers 3
Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde
Co-authored papers 3
Co-authored papers 3
Co-authored papers 3
Co-authored papers 3
University of Cambridge
Co-authored papers 2
Co-authored papers 2
Chalmers University of Technology
Co-authored papers 2
Co-authored papers 2
Co-authored papers 2
University of Manchester
Co-authored papers 2
Heidelberg Institute for Theoretical Studies (HITS gGmbH)
Co-authored papers 2
University of California San Diego
Co-authored papers 2
University of Manchester
Co-authored papers 2
Co-authored papers 2
Newcastle University
Co-authored papers 2