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Author Details

Brian J Capaldo
Center for Cancer Research, National Cancer Institute
2012
20
10
Sarah J Ratcliffe (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
37725435Tumor-derived biomarkers predict efficacy of B7H3 antibody-drug conjugate treatment in metastatic prostate cancer models.J Clin Invest2023
36181613Progression of prostate cancer reprograms MYC-mediated lipid metabolism via lysine methyltransferase 2A.Discov Oncol2022
35393570TMPRSS2-ERG promotes the initiation of prostate cancer by suppressing oncogene-induced senescence.Cancer Gene Ther2022
34568716Metastatic Castration-Resistant Prostate Cancer Remains Dependent on Oncogenic Drivers Found in Primary Tumors.JCO Precis Oncol2021
33785256Nascent Prostate Cancer Heterogeneity Drives Evolution and Resistance to Intense Hormonal Therapy.Eur Urol2021
31171641<i>RUNX3</i> levels in human hematopoietic progenitors are regulated by aging and dictate erythroid-myeloid balance.Haematologica2020
32320734Human T<sub>H</sub>1 and T<sub>H</sub>2 cells targeting rhinovirus and allergen coordinately promote allergic asthma.J Allergy Clin Immunol2020
32371590Targeting the PI3K/AKT Pathway Overcomes Enzalutamide Resistance by Inhibiting Induction of the Glucocorticoid Receptor.Mol Cancer Ther2020
31612215Cardiac resynchronization therapy reduces expression of inflammation-promoting genes related to interleukin-1β in heart failure.Cardiovasc Res2020
30506749An integrated framework using high-dimensional mass cytometry and fluorescent flow cytometry identifies discrete B cell subsets in patients with red meat allergy.Clin Exp Allergy2019
28939412T<sub>H</sub>1 signatures are present in the lower airways of children with severe asthma, regardless of allergic status.J Allergy Clin Immunol2018
29889233Implementation of Mass Cytometry as a Tool for Mechanism of Action Studies in Inflammatory Bowel Disease.Inflamm Bowel Dis2018
30288359Formation and phenotypic characterization of CD49a, CD49b and CD103 expressing CD8 T cell populations in human metastatic melanoma.Oncoimmunology2018
29034364Microenvironmental agonists generate <i>de novo</i> phenotypic resistance to combined ibrutinib plus venetoclax in CLL and MCL.Blood Adv2017
26673621Combinatorial drug screening and molecular profiling reveal diverse mechanisms of intrinsic and adaptive resistance to BRAF inhibition in V600E BRAF mutant melanomas.Oncotarget2016
24986420Synergistic apoptosis in head and neck squamous cell carcinoma cells by co-inhibition of insulin-like growth factor-1 receptor signaling and compensatory signaling pathways.Head Neck2015
26405815Systems Analysis of Adaptive Responses to MAP Kinase Pathway Blockade in BRAF Mutant Melanoma.PLoS One2015
24674868Total synthesis of a functional designer eukaryotic chromosome.Science2014
25033200Identification of a new target of miR-16, Vacuolar Protein Sorting 4a.PLoS One2014
22962324Synthetic lethal screening with small-molecule inhibitors provides a pathway to rational combination therapies for melanoma.Mol Cancer Ther2012
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Collaborators

National Cancer Institute
Co-authored papers 4
HemoShear Therapeutics LLC
Co-authored papers 4
University of Virginia
Co-authored papers 3
Center for Applied Proteomics and Molecular Medicine, George Mason University
Co-authored papers 3
University of Virginia
Co-authored papers 3
University of Virginia School of Medicine
Co-authored papers 2
University of Virginia
Co-authored papers 2
University of Virginia
Co-authored papers 2
College of Optical Science and Engineering, Zhejiang University
Co-authored papers 2
National Cancer Institute, National Institutes of Health
Co-authored papers 2
University of Virginia School of Medicine
Co-authored papers 2
University of Virginia
Co-authored papers 2
University of Illinois at Chicago
Co-authored papers 2
University of Virginia School of Medicine
Co-authored papers 1
Pennsylvania State University, University Park
Co-authored papers 1
College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences
Co-authored papers 1
Co-authored papers 1
University of Virginia School of Medicine
Co-authored papers 1
University of Virginia
Co-authored papers 1
National Cancer Institute, National Institutes of Health
Co-authored papers 1
University of California
Co-authored papers 1
Feinberg School of Medicine Northwestern University
Co-authored papers 1
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Institute for Precision Cardiovascular Medicine
Co-authored papers 1
Institute for Systems Genetics, NYU School of Medicine
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Division of Allergy & Clinical Immunology, University of Virginia
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University of Virginia School of Medicine
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Johns Hopkins University School of Medicine
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Beth Israel Deaconess Medical Center and Harvard Medical School
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University of Minnesota Medical Center
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