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Author Details

Wolfgang Wurst
Institute of Developmental Genetics, German Research Center for Environmental Health
1984
452
90
PMIDPaper TitleJournal TitlePublished Year
36529279Identification of ocular regulatory functions of core histone variant H3.2.Exp Eye Res2023
37996418A reversible state of hypometabolism in a human cellular model of sporadic Parkinson's disease.Nat Commun2023
37988467Unrestrained cleavage of Roquin-1 by MALT1 induces spontaneous T cell activation and the development of autoimmunity.Proc Natl Acad Sci U S A2023
36993625Implication of FOXD2 dysfunction in syndromic congenital anomalies of the kidney and urinary tract (CAKUT).medRxiv2023
37230398AOX delays the onset of the lethal phenotype in a mouse model of Uqcrh (complex III) disease.Biochim Biophys Acta Mol Basis Dis2023
37130781Deletion of SERF2 in mice delays embryonic development and alters amyloid deposit structure in the brain.Life Sci Alliance2023
37428903Systemic deletion of <i>DMD</i> exon 51 rescues clinically severe Duchenne muscular dystrophy in a pig model lacking <i>DMD</i> exon 52.Proc Natl Acad Sci U S A2023
36995669Gene Editing in Mouse Zygotes Using the CRISPR/Cas9 System.Methods Mol Biol2023
36878826Corrigendum to Semaphorin 4C and 4G are ligands of Plexin-B2 required in cerebellar development [Mol. Cell. Neurosci., 2011 Feb;46(2):419-31].Mol Cell Neurosci2023
36538124A rationale for considering heart/brain axis control in neuropsychiatric disease.Mamm Genome2023
34927460Susceptibility to diet-induced obesity at thermoneutral conditions is independent of UCP1.Am J Physiol Endocrinol Metab2022
35373464Parkinson's disease motor symptoms rescue by CRISPRa-reprogramming astrocytes into GABAergic neurons.EMBO Mol Med2022
35370007Chapter 5 - "Parkinson's disease - A role of non-enzymatic posttranslational modifications in disease onset and progression?"Mol Aspects Med2022
35659494Pig models for Duchenne muscular dystrophy - from disease mechanisms to validation of new diagnostic and therapeutic concepts.Neuromuscul Disord2022
35618940PARK7/DJ-1 promotes pyruvate dehydrogenase activity and maintains T<sub>reg</sub> homeostasis during ageing.Nat Metab2022
36535974Toxicity of extracellular alpha-synuclein is independent of intracellular alpha-synuclein.Sci Rep2022
36002575Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation.Nature2022
36369285Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice.Nat Commun2022
36270613Validation of Mct8/Oatp1c1 dKO mice as a model organism for the Allan-Herndon-Dudley Syndrome.Mol Metab2022
35974013Primary cilia and SHH signaling impairments in human and mouse models of Parkinson's disease.Nat Commun2022
35159329Innate Immune Pathways Promote Oligodendrocyte Progenitor Cell Recruitment to the Injury Site in Adult Zebrafish Brain.Cells2022
35308871Concept of the Munich/Augsburg Consortium Precision in Mental Health for the German Center of Mental Health.Front Psychiatry2022
34964047Post-synaptic scaffold protein TANC2 in psychiatric and somatic disease risk.Dis Model Mech2022
33202244CRISPR-Mediated Induction of Neuron-Enriched Mitochondrial Proteins Boosts Direct Glia-to-Neuron Conversion.Cell Stem Cell2021
33597771Simple and reliable detection of CRISPR-induced on-target effects by qgPCR and SNP genotyping.Nat Protoc2021
33512427Mammalian VPS45 orchestrates trafficking through the endosomal system.Blood2021
33729986Mutant non-coding RNA resource in mouse embryonic stem cells.Dis Model Mech2021
33667363CRISPR-Mediated Induction of Neuron-Enriched Mitochondrial Proteins Boosts Direct Glia-to-Neuron Conversion.Cell Stem Cell2021
33531685Genome editing for Duchenne muscular dystrophy: a glimpse of the future?Gene Ther2021
33748099Comprehensive miRNome-Wide Profiling in a Neuronal Cell Model of Synucleinopathy Implies Involvement of Cell Cycle Genes.Front Cell Dev Biol2021
34474098Determination of morphine and norlaudanosoline in murine brain regions by dispersive liquid-liquid micro-extraction and liquid chromatograpy-electrochemical detection.Neurochem Int2021
34811541Disrupting Roquin-1 interaction with Regnase-1 induces autoimmunity and enhances antitumor responses.Nat Immunol2021
34750991Characterising a homozygous two-exon deletion in UQCRH: comparing human and mouse phenotypes.EMBO Mol Med2021
34390512Endoglycan (PODXL2) is proteolytically processed by ADAM10 (a disintegrin and metalloprotease 10) and controls neurite branching in primary neurons.FASEB J2021
34767456TRAF6 prevents fatal inflammation by homeostatic suppression of MALT1 protease.Sci Immunol2021
34532319iPS Cell-Based Model for <i>MAPT</i> Haplotype as a Risk Factor for Human Tauopathies Identifies No Major Differences in TAU Expression.Front Cell Dev Biol2021
34043061A comprehensive phenotypic characterization of a whole-body Wdr45 knock-out mouse.Mamm Genome2021
34083785Non-invasive and high-throughput interrogation of exon-specific isoform expression.Nat Cell Biol2021
33999436Mutations in HID1 Cause Syndromic Infantile Encephalopathy and Hypopituitarism.Ann Neurol2021
33449167DGK and DZHK position paper on genome editing: basic science applications and future perspective.Basic Res Cardiol2021
33131190Diabetes type 2 risk gene Dusp8 is associated with altered sucrose reward behavior in mice and humans.Brain Behav2021
33264576Dose-dependent long-term effects of a single radiation event on behaviour and glial cells.Int J Radiat Biol2021
31591642Soft windowing application to improve analysis of high-throughput phenotyping data.Bioinformatics2020
32060626A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes.Mamm Genome2020
31908000Mouse brain proteomics establishes MDGA1 and CACHD1 as in vivo substrates of the Alzheimer protease BACE1.FASEB J2020
32029747Sox2 controls Schwann cell self-organization through fibronectin fibrillogenesis.Sci Rep2020
32015554Global site-specific neddylation profiling reveals that NEDDylated cofilin regulates actin dynamics.Nat Struct Mol Biol2020
32015326Alpha-synuclein fragments trigger distinct aggregation pathways.Cell Death Dis2020
32066665A truncating Aspm allele leads to a complex cognitive phenotype and region-specific reductions in parvalbuminergic neurons.Transl Psychiatry2020
32103165Publisher Correction: Global site-specific neddylation profiling reveals that NEDDylated cofilin regulates actin dynamics.Nat Struct Mol Biol2020
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Collaborators

Martin Hrab?? de Angelis
German Center for Diabetes Research (DZD e.V.)
Co-authored papers 109
Sabine M H??lter
German Research Centre for Environmental Health
Co-authored papers 85
Valerie Gailus-Durner
Institute of Experimental Genetics, German Mouse Clinic
Co-authored papers 78
Helmut Fuchs
Institute of Experimental Genetics, German Mouse Clinic
Co-authored papers 77
Jan Rozman
German Center for Diabetes Research (DZD)
Co-authored papers 43
Martin Klingenspor
Technical University of Munich
Co-authored papers 39
Steve D M Brown
Mary Lyon Centre Harwell Science and Innovation Campus Oxfordshire UK.
Co-authored papers 14
Glauco P Tocchini-Valentini
Monterotondo Mouse Clinic (MMC), Italian National Research Council (CNR)
Co-authored papers 11
Kent C Lloyd
University of California davis
Co-authored papers 10
Yann Herault
Institut Clinique de la Souris (ICS), Universite de Strasbourg, CNRS, INSERM
Co-authored papers 10
Fabian J Theis
Technical University of Munich
Co-authored papers 10
Janet Rossant
The Hospital for Sick Children
Co-authored papers 10
Colin McKerlie
The Hospital for Sick Children
Co-authored papers 10
Christian Haass
German Center for Neurodegenerative Diseases (DZNE) Munich
Co-authored papers 10
William C Skarnes
Wellcome Trust Sanger Institute
Co-authored papers 10
Jacqueline K White
Wellcome Trust Sanger Institute
Co-authored papers 9
Ann-Marie Mallon
The Turing Institute
Co-authored papers 9
Jeremy Mason
European Molecular Biology Laboratory - European Bioinformatics Institute
Co-authored papers 9
Ann M Flenniken
Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital
Co-authored papers 8
Sara Wells
Mary Lyon Centre at Medical Research Council
Co-authored papers 8
Terrence F Meehan
European Bioinformatics Institute
Co-authored papers 7
Mark Moore
Co-authored papers 7
Paul Flicek
European Bioinformatics Institute
Co-authored papers 7
Helen Parkinson
European Bioinformatics Institute
Co-authored papers 7
Nicole Ehrhardt
University of Washington
Co-authored papers 7
Lauryl M J Nutter
The Hospital for Sick Children
Co-authored papers 7
Tania Sorg
Universite de Strasbourg, CNRS, INSERM, Institut de La Clinique de La Souris
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Allan Bradley
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Release 1.2