Skip to Main Content

Author Details

Olivier Ayrault
Institut Curie, PSL Research University, CNRS UMR, INSERM
2004
66
31
Antoine Forget (CM4AI)
PMIDPaper TitleJournal TitlePublished Year
38062245SALL4 is a CRL3<sup>REN/KCTD11</sup> substrate that drives Sonic Hedgehog-dependent medulloblastoma.Cell Death Differ2024
37377921Longitudinal characterization of primary osteosarcoma and derived subcutaneous and orthotopic relapsed patient-derived xenograft models.Front Oncol2023
37863903Imaging and multi-omics datasets converge to define different neural progenitor origins for ATRT-SHH subgroups.Nat Commun2023
37183219Class I HDAC inhibitor entinostat synergizes with PLK1 inhibitors in MYC-amplified medulloblastoma cells.J Neurooncol2023
37014508Molecular characterisation defines clinically-actionable heterogeneity within Group 4 medulloblastoma and improves disease risk-stratification.Acta Neuropathol2023
37379234Clinical outcome of pediatric medulloblastoma patients with Li-Fraumeni syndrome.Neuro Oncol2023
35199222Immunohistochemistry as a tool to identify ELP1-associated medulloblastoma.Acta Neuropathol2022
35550257Oncogenic chimeric transcription factors drive tumor-specific transcription, processing, and translation of silent genomic regions.Mol Cell2022
35831316The HHIP-AS1 lncRNA promotes tumorigenicity through stabilization of dynein complex 1 in human SHH-driven tumors.Nat Commun2022
35816899Beta-blockers disrupt mitochondrial bioenergetics and increase radiotherapy efficacy independently of beta-adrenergic receptors in medulloblastoma.EBioMedicine2022
36446943Author Correction: Failure of human rhombic lip differentiation underlies medulloblastoma formation.Nature2022
36131014Failure of human rhombic lip differentiation underlies medulloblastoma formation.Nature2022
36352218ClustMMRA v2: A Scalable Computational Pipeline for the Identification of MicroRNA Clusters Acting Cooperatively on Tumor Molecular Subgroups.Adv Exp Med Biol2022
35307743Intratumoral heterogeneity of MYC drives medulloblastoma metastasis and angiogenesis.Neuro Oncol2022
30904166New research directions in medulloblastoma.Neurochirurgie2021
33741928The transcriptional landscape of Shh medulloblastoma.Nat Commun2021
33789110Excitatory granule neuron precursors orchestrate laminar localization and differentiation of cerebellar inhibitory interneuron subtypes.Cell Rep2021
33866410Circular RNA profiling distinguishes medulloblastoma groups and shows aberrant RMST overexpression in WNT medulloblastoma.Acta Neuropathol2021
34409296Clinical and molecular analysis of smoothened inhibitors in Sonic Hedgehog medulloblastoma.Neurooncol Adv2021
33323893Diagnostic Accuracy of a Reduced Immunohistochemical Panel in Medulloblastoma Molecular Subtyping, Correlated to DNA-methylation Analysis.Am J Surg Pathol2021
32296180Germline Elongator mutations in Sonic Hedgehog medulloblastoma.Nature2020
31896080Introduction. Pediatric brain tumor.Neurosurg Focus2020
31819232Medulloblastomics revisited: biological and clinical insights from thousands of patients.Nat Rev Cancer2020
33375523Prognostic Clinical and Biologic Features for Overall Survival after Relapse in Childhood Medulloblastoma.Cancers (Basel)2020
32686664An OTX2-PAX3 signaling axis regulates Group 3 medulloblastoma cell fate.Nat Commun2020
30695697Atoh1 Controls Primary Cilia Formation to Allow for SHH-Triggered Granule Neuron Progenitor Proliferation.Dev Cell2019
31664194Recurrent noncoding U1 snRNA mutations drive cryptic splicing in SHH medulloblastoma.Nature2019
31328883An autocrine ActivinB mechanism drives TGFβ/Activin signaling in Group 3 medulloblastoma.EMBO Mol Med2019
31341163ERAP1 promotes Hedgehog-dependent tumorigenesis by controlling USP47-mediated degradation of βTrCP.Nat Commun2019
30848346SHH medulloblastoma in a young adult with a TCF4 germline pathogenic variation.Acta Neuropathol2019
29533784NRL and CRX Define Photoreceptor Identity and Reveal Subgroup-Specific Dependencies in Medulloblastoma.Cancer Cell2018
30205043Aberrant ERBB4-SRC Signaling as a Hallmark of Group 4 Medulloblastoma Revealed by Integrative Phosphoproteomic Profiling.Cancer Cell2018
28490517ATOH1 Promotes Leptomeningeal Dissemination and Metastasis of Sonic Hedgehog Subgroup Medulloblastomas.Cancer Res2017
28317875Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme.Nat Commun2017
26760213Divergent clonal selection dominates medulloblastoma at recurrence.Nature2016
27418510Return to quiescence of mouse neural stem cells by degradation of a proactivation protein.Science2016
26688373Insights into cerebellar development and medulloblastoma.Bull Cancer2016
26818002The occurrence of intracranial rhabdoid tumours in mice depends on temporal control of Smarcb1 inactivation.Nat Commun2016
25636740MRT-92 inhibits Hedgehog signaling by blocking overlapping binding sites in the transmembrane domain of the Smoothened receptor.FASEB J2015
26578773PML IV/ARF interaction enhances p53 SUMO-1 conjugation, activation, and senescence.Proc Natl Acad Sci U S A2015
26091048Dicer Is Required for Normal Cerebellar Development and to Restrain Medulloblastoma Formation.PLoS One2015
24684846Pemetrexed and gemcitabine as combination therapy for the treatment of Group3 medulloblastoma.Cancer Cell2014
24928431Role of the miR-17⿼92 cluster family in cerebellar and medulloblastoma development.Biol Open2014
24960692Shh signaling protects Atoh1 from degradation mediated by the E3 ubiquitin ligase Huwe1 in neural precursors.Dev Cell2014
24145352Silencing of the miR-17~92 cluster family inhibits medulloblastoma progression.Cancer Res2013
24303070WNT3 inhibits cerebellar granule neuron progenitor proliferation and medulloblastoma formation via MAPK activation.PLoS One2013
22315224Hypermethylated in cancer 1 (HIC1) recruits polycomb repressive complex 2 (PRC2) to a subset of its target genes through interaction with human polycomb-like (hPCL) proteins.J Biol Chem2012
23067406[Subtypes of medulloblastomas: distinct cellular origins].Med Sci (Paris)2012
22573682Age-dependent in vivo conversion of mouse cochlear pillar and Deiters' cells to immature hair cells by Atoh1 ectopic expression.J Neurosci2012
21205878Complex interplay between β-catenin signalling and Notch effectors in intestinal tumorigenesis.Gut2011
  • 1 - 50 of 66

Recommended Authors

Komal S Rathi
Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia
Career Start Year 2014
Number of shared co-authors 9
Jessica M Rusert
University of California San Diego
Career Start Year 2013
Number of shared co-authors 31
Krutika S Gaonkar
Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia
Career Start Year 2012
Number of shared co-authors 7
Adrian M Dubuc
Dana-Farber Cancer Institute
Career Start Year 2008
Number of shared co-authors 87
Henry Yang
Cancer Science Institute of Singapore, National University of Singapore
Career Start Year 2005
Number of shared co-authors 0
Etienne Danis
University of Colorado Anschutz Medical Campus
Career Start Year 2004
Number of shared co-authors 3
Massimo Squatrito
Seve Ballesteros Foundation Brain Tumor group
Career Start Year 2002
Number of shared co-authors 7
Daniel Martinez
Perelman School of Medicine at the University of Pennsylvania
Career Start Year 2002
Number of shared co-authors 12
Adam C Resnick
Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia
Career Start Year 2001
Number of shared co-authors 52
Meihua Li
The First Affiliated Hospital of Nanchang University
Career Start Year 2001
Number of shared co-authors 13
Jan Koster
Amsterdam University Medical Centers location AMC
Career Start Year 1999
Number of shared co-authors 89
Brian R Rood
Brain Tumor Institute, Children's National Hospital
Career Start Year 1998
Number of shared co-authors 52
Robert L Walker
Center for Cancer Research, National Cancer Institute, National Institutes of Health
Career Start Year 1997
Number of shared co-authors 1
Yaoqi Alan Wang
The University of Texas MD Anderson Cancer Center
Career Start Year 1997
Number of shared co-authors 2
Jason D Weber
Washington University School of Medicine
Career Start Year 1996
Number of shared co-authors 5
Kristina A Cole
Perelman School of Medicine, University of Pennsylvania
Career Start Year 1994
Number of shared co-authors 23
Nadia Dahmane
Weill Cornell Medical College
Career Start Year 1994
Number of shared co-authors 1
Julien Sage
Department of Pediatrics Stanford University Stanford California USA.
Career Start Year 1993
Number of shared co-authors 4
Sanja Pajovic
Arthur and Sonia Labatt Brain Tumour Research Centre, The Hospital for Sick Children
Career Start Year 1993
Number of shared co-authors 18
John Easton
St Jude Children's Research Hospital
Career Start Year 1991
Number of shared co-authors 37
Glenn S Cowley
Broad Institute of Harvard and MIT
Career Start Year 1990
Number of shared co-authors 6
Annie Huang
Arthur and Sonia Labatt Brain Tumor Research Centre, Hospital for Sick Children
Career Start Year 1990
Number of shared co-authors 121
Antonio Iavarone
Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami
Career Start Year 1989
Number of shared co-authors 30
Glenn M Marshall
Children's Cancer Institute, Lowy Cancer Research Centre
Career Start Year 1989
Number of shared co-authors 7
E Alejandro Sweet-Cordero
University of California San Francisco
Career Start Year 1989
Number of shared co-authors 14
Eldad Zacksenhaus
University of Toronto
Career Start Year 1988
Number of shared co-authors 10
James F Amatruda
Children's Hospital of Los Angeles
Career Start Year 1988
Number of shared co-authors 7
Ching C Lau
Baylor College of Medicine
Career Start Year 1982
Number of shared co-authors 44
Scott L Pomeroy
Harvard Medical School
Career Start Year 1978
Number of shared co-authors 117
Webster K Cavenee
Ludwig Institute for Cancer Research, University of California San Diego
Career Start Year 1977
Number of shared co-authors 10

Collaborators

Martine F Roussel
St. Jude Children's Research Hospital
Co-authored papers 15
St??phanie Puget
Necker Hospital, Assistance Publique-Hopitaux de Paris
Co-authored papers 14
Antoine Forget (CM4AI)
University of California San Francisco
Co-authored papers 13
Franck Bourdeaut
SIREDO Oncology Center, Institut Curie Hospital, and Universite de Paris
Co-authored papers 13
Stefan M Pfister
Hopp Children's Cancer Center Heidelberg (KiTZ)
Co-authored papers 12
Michael D Taylor
The Hospital for Sick Children
Co-authored papers 12
Frederique Zindy
St. Jude Children's Research Hospital
Co-authored papers 11
Julien Masliah-Planchon
Curie Institute Hospital Group
Co-authored papers 10
Vijay Ramaswamy
Hospital for Sick Children
Co-authored papers 9
Christelle Dufour
Universite Paris-Saclay
Co-authored papers 9
Marc Remke
and Clinical Immunology, Heinrich Heine University, University Hospital Dusseldorf
Co-authored papers 8
Pascale Varlet
Institut de Psychiatrie et Neurosciences de Paris (IPNP), INSERM, University of Paris
Co-authored papers 8
Marcel Kool
Hopp Children's Cancer Center (KiTZ)
Co-authored papers 7
Laure Bihannic
St. Jude Children's Research Hospital
Co-authored papers 7
Olivier Delattre
PSL Research University, Institut Curie Research Center, INSERM U, Institut Curie
Co-authored papers 7
Claudia C Faria
Hospital de Santa Maria, Centro Hospitalar Universitario Lisboa Norte (CHULN)
Co-authored papers 6
David Malkin
Hospital for Sick Children
Co-authored papers 6
Celio Pouponnot
Institut Curie
Co-authored papers 6
Paul A Northcott
St Jude Children's Research Hospital
Co-authored papers 6
Anca Sorana Morrissy
Cumming School of Medicine, University of Calgary
Co-authored papers 6
Florence M G Cavalli
Institut Curie, PSL Research University
Co-authored papers 6
Fran??ois Doz
Institut Curie and University Paris Cite
Co-authored papers 6
Flavia Bernardi
Institut Curie, PSL Research University, CNRS UMR, INSERM
Co-authored papers 6
Andrey Korshunov
Institute of Pathology, University Hospital Heidelberg
Co-authored papers 5
Seung-Ki Kim
Seoul National University Children's Hospital
Co-authored papers 5
Erwin G Van Meir
Heersink School of Medicine, University of Alabama at Birmingham
Co-authored papers 5
Toshihiro Kumabe
Kitasato University School of Medicine
Co-authored papers 5
Betty Luu
University of Wollongong
Co-authored papers 5
Audrey L Mercier
Institut Curie, CNRS UMR 3306, INSERM U1005, Centre Universitaire
Co-authored papers 5
James M Olson
Clinical Research Division, Fred Hutchinson Cancer Center
Co-authored papers 5
Release 1.2